BATF3 — 11 ClinVar variants
All ClinVar germline BATF3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 10 flagged for review →
1 Likely benign · 10 Uncertain significance
Full BATF3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 10
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 6
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- BATF3 p.Ala17Val Uncertain significance Single submitter
- BATF3 p.Asp119Gly Uncertain significance Single submitter
- BATF3 p.Asp34Val Uncertain significance Single submitter
- BATF3 p.Gln72Arg Uncertain significance Single submitter
- BATF3 p.Gly123Ser Uncertain significance Single submitter
- BATF3 p.Leu5Phe Uncertain significance Single submitter
Predictors split 4
The independent predictors disagree with each other — read with care.
All BATF3 variants
Likely benign 1
- p.Met76Val Single submitter
Uncertain significance 10
- p.Ala17Val Single submitter ⚠
- p.Asp119Gly Single submitter ⚠
- p.Asp34Val Single submitter ⚠
- p.Gln72Arg Single submitter ⚠
- p.Gly123Ser Single submitter ⚠
- p.Gly4Arg Single submitter ⚠
- p.Leu5Phe Single submitter ⚠
- p.Lys62Glu Single submitter ⚠
- p.Ser2Trp Single submitter ⚠
- p.Val16Asp Single submitter ⚠