CABP7 — 30 ClinVar variants
All ClinVar germline CABP7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 30 flagged for review →
30 Uncertain significance
Full CABP7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 30
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 23
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CABP7 p.Arg181His Uncertain significance Single submitter
- CABP7 p.Arg80Trp Uncertain significance Single submitter
- CABP7 p.Asn177Lys Uncertain significance Single submitter
- CABP7 p.Asp124Asn Uncertain significance Single submitter
- CABP7 p.Asp84Gly Uncertain significance Single submitter
- CABP7 p.Cys175Arg Uncertain significance Single submitter
- CABP7 p.Glu159Lys Uncertain significance Single submitter
- CABP7 p.Glu166Lys Uncertain significance Single submitter
- CABP7 p.Glu37Asp Uncertain significance Single submitter
- CABP7 p.Glu71Lys Uncertain significance Single submitter
- CABP7 p.Gly49Ser Uncertain significance Single submitter
- CABP7 p.Gly85Asp Uncertain significance Single submitter
- CABP7 p.Ile107Asn Uncertain significance Single submitter
- CABP7 p.Ile204Thr Uncertain significance Single submitter
- CABP7 p.Leu128Pro Uncertain significance Single submitter
- CABP7 p.Lys148Arg Uncertain significance Single submitter
- CABP7 p.Met83Ile Uncertain significance Single submitter
- CABP7 p.Ser212Gly Uncertain significance Single submitter
- CABP7 p.Thr118Ile Uncertain significance Single submitter
- CABP7 p.Thr129Met Uncertain significance Single submitter
- CABP7 p.Thr156Met Uncertain significance Single submitter
- CABP7 p.Thr96Ser Uncertain significance Single submitter
- CABP7 p.Val18Met Uncertain significance Single submitter
Predictors split 7
The independent predictors disagree with each other — read with care.
- CABP7 p.Ala192Thr Uncertain significance Single submitter
- CABP7 p.Ala205Val Uncertain significance Single submitter
- CABP7 p.Arg135Trp Uncertain significance Single submitter
- CABP7 p.Asn50Asp Uncertain significance Single submitter
- CABP7 p.Cys184Tyr Uncertain significance Single submitter
- CABP7 p.Met214Lys Uncertain significance Single submitter
- CABP7 p.Val170Met Uncertain significance Single submitter
All CABP7 variants
Uncertain significance 30
- p.Ala192Thr Single submitter ⚠
- p.Ala205Val Single submitter ⚠
- p.Arg135Trp Single submitter ⚠
- p.Arg181His Single submitter ⚠
- p.Arg80Trp Single submitter ⚠
- p.Asn177Lys Single submitter ⚠
- p.Asn50Asp Single submitter ⚠
- p.Asp124Asn Single submitter ⚠
- p.Asp84Gly Single submitter ⚠
- p.Cys175Arg Single submitter ⚠
- p.Cys184Tyr Single submitter ⚠
- p.Glu159Lys Single submitter ⚠
- p.Glu166Lys Single submitter ⚠
- p.Glu37Asp Single submitter ⚠
- p.Glu71Lys Single submitter ⚠
- p.Gly49Ser Single submitter ⚠
- p.Gly85Asp Single submitter ⚠
- p.Ile107Asn Single submitter ⚠
- p.Ile204Thr Single submitter ⚠
- p.Leu128Pro Single submitter ⚠
- p.Lys148Arg Single submitter ⚠
- p.Met214Lys Single submitter ⚠
- p.Met83Ile Single submitter ⚠
- p.Ser212Gly Single submitter ⚠
- p.Thr118Ile Single submitter ⚠
- p.Thr129Met Single submitter ⚠
- p.Thr156Met Single submitter ⚠
- p.Thr96Ser Single submitter ⚠
- p.Val170Met Single submitter ⚠
- p.Val18Met Single submitter ⚠