CAMK1G — 70 ClinVar variants
All ClinVar germline CAMK1G variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 67 flagged for review →
3 Likely benign · 67 Uncertain significance
Full CAMK1G gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 67
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 46
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CAMK1G p.Ala271Asp Uncertain significance Single submitter
- CAMK1G p.Ala271Thr Uncertain significance Single submitter
- CAMK1G p.Ala467Val Uncertain significance Single submitter
- CAMK1G p.Ala70Pro Uncertain significance Single submitter
- CAMK1G p.Ala70Thr Uncertain significance Single submitter
- CAMK1G p.Arg108Gln Uncertain significance Single submitter
- CAMK1G p.Arg112Leu Uncertain significance Single submitter
- CAMK1G p.Arg318Lys Uncertain significance Single submitter
- CAMK1G p.Arg379His Uncertain significance Single submitter
- CAMK1G p.Arg380Gln Uncertain significance Single submitter
- CAMK1G p.Arg380Gly Uncertain significance Single submitter
- CAMK1G p.Arg466Gln Uncertain significance Single submitter
- CAMK1G p.Asn148Lys Uncertain significance Single submitter
- CAMK1G p.Asn148Ser Uncertain significance Single submitter
- CAMK1G p.Asn280Ser Uncertain significance Single submitter
- CAMK1G p.Asn335Lys Uncertain significance Single submitter
- CAMK1G p.Asp244His Uncertain significance Single submitter
- CAMK1G p.Asp85Tyr Uncertain significance Single submitter
- CAMK1G p.Cys465Tyr Uncertain significance Single submitter
- CAMK1G p.Glu264Lys Uncertain significance Single submitter
- CAMK1G p.Glu334Asp Uncertain significance Single submitter
- CAMK1G p.Gly206Ser Uncertain significance Single submitter
- CAMK1G p.Gly426Glu Uncertain significance Single submitter
- CAMK1G p.Gly426Trp Uncertain significance Single submitter
- CAMK1G p.His407Arg Uncertain significance Single submitter
- CAMK1G p.His407Tyr Uncertain significance Single submitter
- CAMK1G p.Ile160Thr Uncertain significance Single submitter
- CAMK1G p.Ile355Val Uncertain significance Single submitter
- CAMK1G p.Ile425Thr Uncertain significance Single submitter
- CAMK1G p.Ile69Thr Uncertain significance Single submitter
- CAMK1G p.Leu48His Uncertain significance Single submitter
- CAMK1G p.Lys428Arg Uncertain significance Single submitter
- CAMK1G p.Met454Ile Uncertain significance Single submitter
- CAMK1G p.Phe106Ser Uncertain significance Single submitter
- CAMK1G p.Pro337Leu Uncertain significance Single submitter
- CAMK1G p.Pro351Leu Uncertain significance Single submitter
- CAMK1G p.Ser326Gly Uncertain significance Single submitter
- CAMK1G p.Ser349Gly Uncertain significance Single submitter
- CAMK1G p.Ser364Arg Uncertain significance Single submitter
- CAMK1G p.Ser421Arg Uncertain significance Single submitter
- CAMK1G p.Ser431Pro Uncertain significance Single submitter
- CAMK1G p.Ser451Pro Uncertain significance Single submitter
- CAMK1G p.Thr371Asn Uncertain significance Single submitter
- CAMK1G p.Trp12Arg Uncertain significance Single submitter
- CAMK1G p.Tyr216Cys Uncertain significance Single submitter
- CAMK1G p.Tyr220Cys Uncertain significance Single submitter
Predictors split 21
The independent predictors disagree with each other — read with care.
- CAMK1G p.Ala307Val Uncertain significance Single submitter
- CAMK1G p.Arg112Gln Uncertain significance Single submitter
- CAMK1G p.Arg20Trp Uncertain significance Single submitter
- CAMK1G p.Arg285Gln Uncertain significance Single submitter
- CAMK1G p.Arg380Trp Uncertain significance Single submitter
- CAMK1G p.Arg466Trp Uncertain significance Single submitter
- CAMK1G p.Arg61Trp Uncertain significance Single submitter
- CAMK1G p.Asn18Ser Uncertain significance Single submitter
- CAMK1G p.Glu339Lys Uncertain significance Single submitter
- CAMK1G p.Glu36Gln Uncertain significance Single submitter
- CAMK1G p.Gly2Arg Uncertain significance Single submitter
- CAMK1G p.Gly409Trp Uncertain significance Single submitter
- CAMK1G p.Leu48Phe Uncertain significance Single submitter
- CAMK1G p.Lys260Asn Uncertain significance Single submitter
- CAMK1G p.Lys297Asn Uncertain significance Single submitter
- CAMK1G p.Lys76Arg Uncertain significance Single submitter
- CAMK1G p.Met322Lys Uncertain significance Single submitter
- CAMK1G p.Ser129Leu Uncertain significance Single submitter
- CAMK1G p.Ser302Ile Uncertain significance Single submitter
- CAMK1G p.Thr223Met Uncertain significance Single submitter
- CAMK1G p.Val314Leu Uncertain significance Single submitter
All CAMK1G variants
Likely benign 3
- p.Ile175Val Single submitter
- p.Ser129= Single submitter
- p.Ser460Gly Single submitter
Uncertain significance 67
- p.Ala271Asp Single submitter ⚠
- p.Ala271Thr Single submitter ⚠
- p.Ala307Val Single submitter ⚠
- p.Ala467Val Single submitter ⚠
- p.Ala70Pro Single submitter ⚠
- p.Ala70Thr Single submitter ⚠
- p.Arg108Gln Single submitter ⚠
- p.Arg112Gln Single submitter ⚠
- p.Arg112Leu Single submitter ⚠
- p.Arg20Trp Single submitter ⚠
- p.Arg285Gln Single submitter ⚠
- p.Arg318Lys Single submitter ⚠
- p.Arg379His Single submitter ⚠
- p.Arg380Gln Single submitter ⚠
- p.Arg380Gly Single submitter ⚠
- p.Arg380Trp Single submitter ⚠
- p.Arg466Gln Single submitter ⚠
- p.Arg466Trp Single submitter ⚠
- p.Arg61Trp Single submitter ⚠
- p.Asn148Lys Single submitter ⚠
- p.Asn148Ser Single submitter ⚠
- p.Asn18Ser Single submitter ⚠
- p.Asn280Ser Single submitter ⚠
- p.Asn335Lys Single submitter ⚠
- p.Asp244His Single submitter ⚠
- p.Asp85Tyr Single submitter ⚠
- p.Cys465Tyr Single submitter ⚠
- p.Glu264Lys Single submitter ⚠
- p.Glu334Asp Single submitter ⚠
- p.Glu339Lys Single submitter ⚠
- p.Glu36Gln Single submitter ⚠
- p.Gly206Ser Single submitter ⚠
- p.Gly2Arg Single submitter ⚠
- p.Gly409Trp Single submitter ⚠
- p.Gly426Glu Single submitter ⚠
- p.Gly426Trp Single submitter ⚠
- p.His407Arg Single submitter ⚠
- p.His407Tyr Single submitter ⚠
- p.Ile160Thr Single submitter ⚠
- p.Ile355Val Single submitter ⚠
- p.Ile425Thr Single submitter ⚠
- p.Ile69Thr Single submitter ⚠
- p.Leu48His Single submitter ⚠
- p.Leu48Phe Single submitter ⚠
- p.Lys260Asn Single submitter ⚠
- p.Lys297Asn Single submitter ⚠
- p.Lys428Arg Single submitter ⚠
- p.Lys76Arg Single submitter ⚠
- p.Met322Lys Single submitter ⚠
- p.Met454Ile Single submitter ⚠
- p.Phe106Ser Single submitter ⚠
- p.Pro337Leu Single submitter ⚠
- p.Pro351Leu Single submitter ⚠
- p.Ser129Leu Single submitter ⚠
- p.Ser302Ile Single submitter ⚠
- p.Ser326Gly Single submitter ⚠
- p.Ser349Gly Single submitter ⚠
- p.Ser364Arg Single submitter ⚠
- p.Ser421Arg Single submitter ⚠
- p.Ser431Pro Single submitter ⚠
- p.Ser451Pro Single submitter ⚠
- p.Thr223Met Single submitter ⚠
- p.Thr371Asn Single submitter ⚠
- p.Trp12Arg Single submitter ⚠
- p.Tyr216Cys Single submitter ⚠
- p.Tyr220Cys Single submitter ⚠
- p.Val314Leu Single submitter ⚠