CCNDBP1 — 47 ClinVar variants
All ClinVar germline CCNDBP1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 44 flagged for review →
3 Likely benign · 44 Uncertain significance
Full CCNDBP1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 44
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 29
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CCNDBP1 p.Ala121Thr Uncertain significance Multiple submitters
- CCNDBP1 p.Ala158Val Uncertain significance Single submitter
- CCNDBP1 p.Ala246Ser Uncertain significance Single submitter
- CCNDBP1 p.Arg119Gln Uncertain significance Single submitter
- CCNDBP1 p.Arg305Gln Uncertain significance Single submitter
- CCNDBP1 p.Asn147Ile Uncertain significance Single submitter
- CCNDBP1 p.Asn228Ser Uncertain significance Single submitter
- CCNDBP1 p.Asp124Gly Uncertain significance Single submitter
- CCNDBP1 p.Asp236Asn Uncertain significance Single submitter
- CCNDBP1 p.Glu192Ala Uncertain significance Single submitter
- CCNDBP1 p.Glu283Ala Uncertain significance Single submitter
- CCNDBP1 p.Glu352Asp Uncertain significance Single submitter
- CCNDBP1 p.Glu39Gln Uncertain significance Single submitter
- CCNDBP1 p.Gly224Glu Uncertain significance Single submitter
- CCNDBP1 p.Ile112Met Uncertain significance Single submitter
- CCNDBP1 p.Ile112Ser Uncertain significance Single submitter
- CCNDBP1 p.Ile284Asn Uncertain significance Single submitter
- CCNDBP1 p.Leu204Phe Uncertain significance Single submitter
- CCNDBP1 p.Leu70Val Uncertain significance Single submitter
- CCNDBP1 p.Leu77Phe Uncertain significance Single submitter
- CCNDBP1 p.Lys323Glu Uncertain significance Single submitter
- CCNDBP1 p.Met176Thr Uncertain significance Single submitter
- CCNDBP1 p.Met51Lys Uncertain significance Single submitter
- CCNDBP1 p.Pro163Thr Uncertain significance Single submitter
- CCNDBP1 p.Thr43Ser Uncertain significance Single submitter
- CCNDBP1 p.Thr85Ala Uncertain significance Single submitter
- CCNDBP1 p.Val195Ala Uncertain significance Single submitter
- CCNDBP1 p.Val61Met Uncertain significance Single submitter
- CCNDBP1 p.Val63Leu Uncertain significance Single submitter
Predictors split 15
The independent predictors disagree with each other — read with care.
- CCNDBP1 p.Ala246Val Uncertain significance Single submitter
- CCNDBP1 p.Arg22Pro Uncertain significance Single submitter
- CCNDBP1 p.Arg29Gln Uncertain significance Single submitter
- CCNDBP1 p.Arg36Trp Uncertain significance Single submitter
- CCNDBP1 p.Asp344Val Uncertain significance Single submitter
- CCNDBP1 p.Gln20Arg Uncertain significance Single submitter
- CCNDBP1 p.Leu56Val Uncertain significance Single submitter
- CCNDBP1 p.Met133Thr Uncertain significance Single submitter
- CCNDBP1 p.Pro33Thr Uncertain significance Single submitter
- CCNDBP1 p.Pro7Leu Uncertain significance Single submitter
- CCNDBP1 p.Thr322Lys Uncertain significance Single submitter
- CCNDBP1 p.Thr85Asn Uncertain significance Single submitter
- CCNDBP1 p.Val155Ala Uncertain significance Single submitter
- CCNDBP1 p.Val184Leu Uncertain significance Single submitter
- CCNDBP1 p.Val304Met Uncertain significance Single submitter
All CCNDBP1 variants
Likely benign 3
- p.Gln229Arg Single submitter
- p.Tyr152Cys Single submitter
- p.Val138Ile Single submitter
Uncertain significance 44
- p.Ala121Thr Multiple submitters ⚠
- p.Ala158Val Single submitter ⚠
- p.Ala246Ser Single submitter ⚠
- p.Ala246Val Single submitter ⚠
- p.Arg119Gln Single submitter ⚠
- p.Arg22Pro Single submitter ⚠
- p.Arg29Gln Single submitter ⚠
- p.Arg305Gln Single submitter ⚠
- p.Arg36Trp Single submitter ⚠
- p.Asn147Ile Single submitter ⚠
- p.Asn228Ser Single submitter ⚠
- p.Asp124Gly Single submitter ⚠
- p.Asp236Asn Single submitter ⚠
- p.Asp344Val Single submitter ⚠
- p.Gln20Arg Single submitter ⚠
- p.Glu192Ala Single submitter ⚠
- p.Glu283Ala Single submitter ⚠
- p.Glu352Asp Single submitter ⚠
- p.Glu39Gln Single submitter ⚠
- p.Gly224Glu Single submitter ⚠
- p.Ile112Met Single submitter ⚠
- p.Ile112Ser Single submitter ⚠
- p.Ile284Asn Single submitter ⚠
- p.Leu204Phe Single submitter ⚠
- p.Leu56Val Single submitter ⚠
- p.Leu70Val Single submitter ⚠
- p.Leu77Phe Single submitter ⚠
- p.Lys323Glu Single submitter ⚠
- p.Met133Thr Single submitter ⚠
- p.Met176Thr Single submitter ⚠
- p.Met51Lys Single submitter ⚠
- p.Pro163Thr Single submitter ⚠
- p.Pro33Thr Single submitter ⚠
- p.Pro7Leu Single submitter ⚠
- p.Thr322Lys Single submitter ⚠
- p.Thr43Ser Single submitter ⚠
- p.Thr85Ala Single submitter ⚠
- p.Thr85Asn Single submitter ⚠
- p.Val155Ala Single submitter ⚠
- p.Val184Leu Single submitter ⚠
- p.Val195Ala Single submitter ⚠
- p.Val304Met Single submitter ⚠
- p.Val61Met Single submitter ⚠
- p.Val63Leu Single submitter ⚠