CEACAM19 — 29 ClinVar variants
All ClinVar germline CEACAM19 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 28 flagged for review →
2 Likely benign · 27 Uncertain significance
Full CEACAM19 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 28
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 17
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CEACAM19 p.Ala112Thr Uncertain significance Single submitter
- CEACAM19 p.Ala235Ser Uncertain significance Single submitter
- CEACAM19 p.Asp237Val Uncertain significance Single submitter
- CEACAM19 p.Gln139Arg Uncertain significance Single submitter
- CEACAM19 p.Gln42His Uncertain significance Single submitter
- CEACAM19 p.Gln61Lys Uncertain significance Single submitter
- CEACAM19 p.Glu41Asp Uncertain significance Single submitter
- CEACAM19 p.Glu69Lys Uncertain significance Single submitter
- CEACAM19 p.Gly29Ser Uncertain significance Single submitter
- CEACAM19 p.His151Pro Uncertain significance Single submitter
- CEACAM19 p.Leu285Pro Uncertain significance Single submitter
- CEACAM19 p.Met132Thr Uncertain significance Single submitter
- CEACAM19 p.Met221Arg Uncertain significance Single submitter
- CEACAM19 p.Pro245Arg Uncertain significance Single submitter
- CEACAM19 p.Pro269Ala Uncertain significance Single submitter
- CEACAM19 p.Thr150Ser Uncertain significance Single submitter
- CEACAM19 p.Thr59Ile Uncertain significance Single submitter
Predictors split 11
The independent predictors disagree with each other — read with care.
- CEACAM19 p.Arg110His Uncertain significance Single submitter
- CEACAM19 p.Arg111His Likely benign Single submitter
- CEACAM19 p.Arg264Trp Uncertain significance Single submitter
- CEACAM19 p.Asn46Lys Uncertain significance Single submitter
- CEACAM19 p.Cys176Tyr Uncertain significance Single submitter
- CEACAM19 p.Gly73Arg Uncertain significance Single submitter
- CEACAM19 p.His191Tyr Uncertain significance Single submitter
- CEACAM19 p.Ile164Phe Uncertain significance Single submitter
- CEACAM19 p.Leu159Arg Uncertain significance Single submitter
- CEACAM19 p.Phe60Leu Uncertain significance Single submitter
- CEACAM19 p.Trp25Arg Uncertain significance Single submitter
All CEACAM19 variants
Likely benign 2
- p.Arg111His Single submitter ⚠
- p.Thr71Met Single submitter
Uncertain significance 27
- p.Ala112Thr Single submitter ⚠
- p.Ala235Ser Single submitter ⚠
- p.Arg110His Single submitter ⚠
- p.Arg264Trp Single submitter ⚠
- p.Asn46Lys Single submitter ⚠
- p.Asp237Val Single submitter ⚠
- p.Cys176Tyr Single submitter ⚠
- p.Gln139Arg Single submitter ⚠
- p.Gln42His Single submitter ⚠
- p.Gln61Lys Single submitter ⚠
- p.Glu41Asp Single submitter ⚠
- p.Glu69Lys Single submitter ⚠
- p.Gly29Ser Single submitter ⚠
- p.Gly73Arg Single submitter ⚠
- p.His151Pro Single submitter ⚠
- p.His191Tyr Single submitter ⚠
- p.Ile164Phe Single submitter ⚠
- p.Leu159Arg Single submitter ⚠
- p.Leu285Pro Single submitter ⚠
- p.Met132Thr Single submitter ⚠
- p.Met221Arg Single submitter ⚠
- p.Phe60Leu Single submitter ⚠
- p.Pro245Arg Single submitter ⚠
- p.Pro269Ala Single submitter ⚠
- p.Thr150Ser Single submitter ⚠
- p.Thr59Ile Single submitter ⚠
- p.Trp25Arg Single submitter ⚠