CEACAM7 — 44 ClinVar variants
All ClinVar germline CEACAM7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 42 flagged for review →
3 Likely benign · 41 Uncertain significance
Full CEACAM7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 42
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 18
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CEACAM7 p.Ala251Thr Uncertain significance Single submitter
- CEACAM7 p.Ala46Thr Uncertain significance Single submitter
- CEACAM7 p.Ala6Thr Uncertain significance Single submitter
- CEACAM7 p.Arg235His Uncertain significance Single submitter
- CEACAM7 p.Asn156Ser Uncertain significance Single submitter
- CEACAM7 p.Asn233Tyr Uncertain significance Single submitter
- CEACAM7 p.Cys168Gly Uncertain significance Single submitter
- CEACAM7 p.Glu237Val Uncertain significance Single submitter
- CEACAM7 p.Ile102Val Uncertain significance Single submitter
- CEACAM7 p.Ile256Thr Uncertain significance Single submitter
- CEACAM7 p.Leu201Pro Uncertain significance Single submitter
- CEACAM7 p.Pro4Leu Uncertain significance Single submitter
- CEACAM7 p.Pro8Thr Uncertain significance Single submitter
- CEACAM7 p.Ser87Arg Uncertain significance Single submitter
- CEACAM7 p.Trp179Ser Uncertain significance Single submitter
- CEACAM7 p.Tyr214Cys Uncertain significance Single submitter
- CEACAM7 p.Val125Ile Uncertain significance Single submitter
- CEACAM7 p.Val54Ile Uncertain significance Single submitter
Predictors split 24
The independent predictors disagree with each other — read with care.
- CEACAM7 p.Ala46Ser Uncertain significance Single submitter
- CEACAM7 p.Arg226Cys Uncertain significance Single submitter
- CEACAM7 p.Arg99Gln Uncertain significance Single submitter
- CEACAM7 p.Asn32Lys Uncertain significance Single submitter
- CEACAM7 p.Asn44Ser Uncertain significance Single submitter
- CEACAM7 p.Asn61Tyr Uncertain significance Single submitter
- CEACAM7 p.Gln111Lys Uncertain significance Single submitter
- CEACAM7 p.Glu159Lys Uncertain significance Single submitter
- CEACAM7 p.Glu47Gln Uncertain significance Single submitter
- CEACAM7 p.Gly70Val Uncertain significance Single submitter
- CEACAM7 p.Gly81Arg Uncertain significance Single submitter
- CEACAM7 p.Gly93Trp Uncertain significance Single submitter
- CEACAM7 p.Gly98Ser Uncertain significance Single submitter
- CEACAM7 p.His96Leu Uncertain significance Single submitter
- CEACAM7 p.Ile80Thr Uncertain significance Single submitter
- CEACAM7 p.Leu166Val Uncertain significance Single submitter
- CEACAM7 p.Leu19Val Uncertain significance Single submitter
- CEACAM7 p.Pro42Leu Uncertain significance Single submitter
- CEACAM7 p.Pro92Ser Uncertain significance Single submitter
- CEACAM7 p.Thr107Ile Uncertain significance Single submitter
- CEACAM7 p.Thr122Asn Uncertain significance Single submitter
- CEACAM7 p.Thr172Ile Uncertain significance Single submitter
- CEACAM7 p.Tyr65Cys Uncertain significance Single submitter
- CEACAM7 p.Val165Ala Likely benign Single submitter
All CEACAM7 variants
Likely benign 3
- p.Ile211Thr Single submitter
- p.Ser205= Single submitter
- p.Val165Ala Single submitter ⚠
Uncertain significance 41
- p.Ala251Thr Single submitter ⚠
- p.Ala46Ser Single submitter ⚠
- p.Ala46Thr Single submitter ⚠
- p.Ala6Thr Single submitter ⚠
- p.Arg226Cys Single submitter ⚠
- p.Arg235His Single submitter ⚠
- p.Arg99Gln Single submitter ⚠
- p.Asn156Ser Single submitter ⚠
- p.Asn233Tyr Single submitter ⚠
- p.Asn32Lys Single submitter ⚠
- p.Asn44Ser Single submitter ⚠
- p.Asn61Tyr Single submitter ⚠
- p.Cys168Gly Single submitter ⚠
- p.Gln111Lys Single submitter ⚠
- p.Glu159Lys Single submitter ⚠
- p.Glu237Val Single submitter ⚠
- p.Glu47Gln Single submitter ⚠
- p.Gly70Val Single submitter ⚠
- p.Gly81Arg Single submitter ⚠
- p.Gly93Trp Single submitter ⚠
- p.Gly98Ser Single submitter ⚠
- p.His96Leu Single submitter ⚠
- p.Ile102Val Single submitter ⚠
- p.Ile256Thr Single submitter ⚠
- p.Ile80Thr Single submitter ⚠
- p.Leu166Val Single submitter ⚠
- p.Leu19Val Single submitter ⚠
- p.Leu201Pro Single submitter ⚠
- p.Pro42Leu Single submitter ⚠
- p.Pro4Leu Single submitter ⚠
- p.Pro8Thr Single submitter ⚠
- p.Pro92Ser Single submitter ⚠
- p.Ser87Arg Single submitter ⚠
- p.Thr107Ile Single submitter ⚠
- p.Thr122Asn Single submitter ⚠
- p.Thr172Ile Single submitter ⚠
- p.Trp179Ser Single submitter ⚠
- p.Tyr214Cys Single submitter ⚠
- p.Tyr65Cys Single submitter ⚠
- p.Val125Ile Single submitter ⚠
- p.Val54Ile Single submitter ⚠