DCANP1 — 49 ClinVar variants
All ClinVar germline DCANP1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 43 flagged for review →
6 Likely benign · 43 Uncertain significance
Full DCANP1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 43
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 38
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DCANP1 p.Ala102Thr Uncertain significance Single submitter
- DCANP1 p.Ala154Thr Uncertain significance Single submitter
- DCANP1 p.Ala202Thr Uncertain significance Single submitter
- DCANP1 p.Arg118Lys Uncertain significance Single submitter
- DCANP1 p.Arg125Gln Uncertain significance Single submitter
- DCANP1 p.Arg137Gly Uncertain significance Single submitter
- DCANP1 p.Arg237Cys Uncertain significance Single submitter
- DCANP1 p.Arg238Lys Uncertain significance Single submitter
- DCANP1 p.Asn192Tyr Uncertain significance Single submitter
- DCANP1 p.Asn195Ser Uncertain significance Single submitter
- DCANP1 p.Gln157His Uncertain significance Single submitter
- DCANP1 p.Gln24Leu Uncertain significance Single submitter
- DCANP1 p.Glu36Gly Uncertain significance Single submitter
- DCANP1 p.Glu83Gln Uncertain significance Single submitter
- DCANP1 p.Gly16Ser Uncertain significance Single submitter
- DCANP1 p.Gly39Glu Uncertain significance Single submitter
- DCANP1 p.Gly62Ala Uncertain significance Single submitter
- DCANP1 p.His206Arg Uncertain significance Single submitter
- DCANP1 p.His236Tyr Uncertain significance Single submitter
- DCANP1 p.His23Asn Uncertain significance Single submitter
- DCANP1 p.His41Gln Uncertain significance Single submitter
- DCANP1 p.Leu153Val Uncertain significance Single submitter
- DCANP1 p.Leu155Val Uncertain significance Single submitter
- DCANP1 p.Leu233Val Uncertain significance Single submitter
- DCANP1 p.Leu26Pro Uncertain significance Single submitter
- DCANP1 p.Leu53Arg Uncertain significance Single submitter
- DCANP1 p.Leu98Ile Uncertain significance Single submitter
- DCANP1 p.Pro243Arg Uncertain significance Single submitter
- DCANP1 p.Pro55His Uncertain significance Single submitter
- DCANP1 p.Pro55Ser Uncertain significance Single submitter
- DCANP1 p.Pro59Ala Uncertain significance Single submitter
- DCANP1 p.Ser205Leu Uncertain significance Single submitter
- DCANP1 p.Ser42Pro Uncertain significance Single submitter
- DCANP1 p.Thr120Ala Uncertain significance Single submitter
- DCANP1 p.Thr213Ile Uncertain significance Single submitter
- DCANP1 p.Trp184Arg Uncertain significance Single submitter
- DCANP1 p.Val146Ile Uncertain significance Single submitter
- DCANP1 p.Val222Gly Uncertain significance Single submitter
Predictors split 5
The independent predictors disagree with each other — read with care.
All DCANP1 variants
Likely benign 6
- p.Ala104Val Single submitter
- p.Glu168Lys Single submitter
- p.Leu212Phe Single submitter
- p.Phe37Ser Single submitter
- p.Pro140Leu Single submitter
- p.Tyr68Ser Single submitter
Uncertain significance 43
- p.Ala102Thr Single submitter ⚠
- p.Ala154Thr Single submitter ⚠
- p.Ala202Thr Single submitter ⚠
- p.Arg118Lys Single submitter ⚠
- p.Arg125Gln Single submitter ⚠
- p.Arg137Gly Single submitter ⚠
- p.Arg237Cys Single submitter ⚠
- p.Arg238Lys Single submitter ⚠
- p.Asn192Tyr Single submitter ⚠
- p.Asn195Ser Single submitter ⚠
- p.Gln157His Single submitter ⚠
- p.Gln24Leu Single submitter ⚠
- p.Glu36Gly Single submitter ⚠
- p.Glu83Gln Single submitter ⚠
- p.Gly16Ser Single submitter ⚠
- p.Gly32Trp Single submitter ⚠
- p.Gly39Glu Single submitter ⚠
- p.Gly62Ala Single submitter ⚠
- p.His206Arg Single submitter ⚠
- p.His236Tyr Single submitter ⚠
- p.His23Asn Single submitter ⚠
- p.His41Gln Single submitter ⚠
- p.Leu153Val Single submitter ⚠
- p.Leu155Met Single submitter ⚠
- p.Leu155Val Single submitter ⚠
- p.Leu233Val Single submitter ⚠
- p.Leu26Pro Single submitter ⚠
- p.Leu53Arg Single submitter ⚠
- p.Leu56Met Single submitter ⚠
- p.Leu98Ile Single submitter ⚠
- p.Pro243Arg Single submitter ⚠
- p.Pro55His Single submitter ⚠
- p.Pro55Ser Single submitter ⚠
- p.Pro59Ala Single submitter ⚠
- p.Ser205Leu Single submitter ⚠
- p.Ser42Pro Single submitter ⚠
- p.Ser42Tyr Single submitter ⚠
- p.Thr120Ala Single submitter ⚠
- p.Thr213Ile Single submitter ⚠
- p.Trp184Arg Single submitter ⚠
- p.Val146Ile Single submitter ⚠
- p.Val222Gly Single submitter ⚠
- p.Val242Met Single submitter ⚠