FABP5 — 18 ClinVar variants
All ClinVar germline FABP5 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 17 flagged for review →
1 Benign · 17 Uncertain significance
Full FABP5 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 17
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 15
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- FABP5 p.Arg12His Uncertain significance Single submitter
- FABP5 p.Arg33Gln Uncertain significance Single submitter
- FABP5 p.Gln5His Uncertain significance Single submitter
- FABP5 p.Gln5Lys Uncertain significance Single submitter
- FABP5 p.Glu8Lys Uncertain significance Single submitter
- FABP5 p.Gly29Glu Uncertain significance Single submitter
- FABP5 p.Gly9Arg Uncertain significance Single submitter
- FABP5 p.Ile44Val Uncertain significance Single submitter
- FABP5 p.Lys50Glu Uncertain significance Single submitter
- FABP5 p.Met23Val Uncertain significance Single submitter
- FABP5 p.Phe89Val Uncertain significance Single submitter
- FABP5 p.Thr126Ala Uncertain significance Single submitter
- FABP5 p.Thr90Ala Uncertain significance Single submitter
- FABP5 p.Tyr131Cys Uncertain significance Single submitter
- FABP5 p.Val121Ile Uncertain significance Single submitter
Predictors split 2
The independent predictors disagree with each other — read with care.
All FABP5 variants
Benign 1
- p.His97Tyr Single submitter ⚠
Uncertain significance 17
- p.Arg12His Single submitter ⚠
- p.Arg33Gln Single submitter ⚠
- p.Gln5His Single submitter ⚠
- p.Gln5Lys Single submitter ⚠
- p.Glu132Val Single submitter
- p.Glu8Lys Single submitter ⚠
- p.Gly29Glu Single submitter ⚠
- p.Gly9Arg Single submitter ⚠
- p.His97Leu Single submitter ⚠
- p.Ile44Val Single submitter ⚠
- p.Lys50Glu Single submitter ⚠
- p.Met23Val Single submitter ⚠
- p.Phe89Val Single submitter ⚠
- p.Thr126Ala Single submitter ⚠
- p.Thr90Ala Single submitter ⚠
- p.Tyr131Cys Single submitter ⚠
- p.Val121Ile Single submitter ⚠