Sugi Variant

Sugi Variant/FAT2

FAT2 — 1569 ClinVar variants

All ClinVar germline FAT2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 686 flagged for review →

1 Likely pathogenic · 78 Conflicting · 110 Benign · 47 Benign/Likely benign · 375 Likely benign · 958 Uncertain significance

Full FAT2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 686

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 62

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 602

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 602

Predictors split 22

The independent predictors disagree with each other — read with care.

All FAT2 variants

Likely pathogenic 1

Conflicting classifications of pathogenicity 78

Benign 110

Benign/Likely benign 47

Likely benign 375

Showing the top 300 by review status; the full set is in the sitemap.

Uncertain significance 958

Showing the top 300 by review status; the full set is in the sitemap.