NUMA1 — 326 ClinVar variants
All ClinVar germline NUMA1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 267 flagged for review →
1 Pathogenic · 3 Conflicting · 12 Benign · 3 Benign/Likely benign · 41 Likely benign · 266 Uncertain significance
Full NUMA1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 267
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors agree, ClinVar conflicts 2
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
Predictors lean, ClinVar uncertain 201
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 201
- NUMA1 p.Ala1075Ser Uncertain significance Single submitter
- NUMA1 p.Ala10Val Uncertain significance Single submitter
- NUMA1 p.Ala1102Thr Uncertain significance Single submitter
- NUMA1 p.Ala1124Thr Uncertain significance Single submitter
- NUMA1 p.Ala1152Val Uncertain significance Single submitter
- NUMA1 p.Ala1220Gly Uncertain significance Single submitter
- NUMA1 p.Ala1319Thr Uncertain significance Single submitter
- NUMA1 p.Ala1331Val Uncertain significance Single submitter
- NUMA1 p.Ala1376Thr Uncertain significance Single submitter
- NUMA1 p.Ala1392Thr Uncertain significance Single submitter
- NUMA1 p.Ala1510Val Uncertain significance Single submitter
- NUMA1 p.Ala1574Asp Uncertain significance Single submitter
- NUMA1 p.Ala1714Pro Uncertain significance Single submitter
- NUMA1 p.Ala1807Thr Uncertain significance Single submitter
- NUMA1 p.Ala1843Pro Uncertain significance Single submitter
- NUMA1 p.Ala2006Val Uncertain significance Single submitter
- NUMA1 p.Ala2102Thr Uncertain significance Single submitter
- NUMA1 p.Ala340Val Uncertain significance Single submitter
- NUMA1 p.Ala426Thr Uncertain significance Single submitter
- NUMA1 p.Ala488Thr Uncertain significance Single submitter
- NUMA1 p.Ala571Val Uncertain significance Single submitter
- NUMA1 p.Ala582Thr Uncertain significance Single submitter
- NUMA1 p.Ala594Val Uncertain significance Single submitter
- NUMA1 p.Ala5Val Uncertain significance Single submitter
- NUMA1 p.Ala646Gly Uncertain significance Single submitter
- NUMA1 p.Ala769Val Uncertain significance Single submitter
- NUMA1 p.Ala812Gly Uncertain significance Single submitter
- NUMA1 p.Ala9Thr Uncertain significance Single submitter
- NUMA1 p.Arg1033Gln Uncertain significance Single submitter
- NUMA1 p.Arg1033Trp Uncertain significance Single submitter
- NUMA1 p.Arg1126Trp Uncertain significance Single submitter
- NUMA1 p.Arg1148Cys Uncertain significance Single submitter
- NUMA1 p.Arg1157Trp Uncertain significance Single submitter
- NUMA1 p.Arg1190Gln Uncertain significance Single submitter
- NUMA1 p.Arg1196Cys Uncertain significance Single submitter
- NUMA1 p.Arg1239Cys Uncertain significance Single submitter
- NUMA1 p.Arg1239His Uncertain significance Single submitter
- NUMA1 p.Arg1282Lys Uncertain significance Single submitter
- NUMA1 p.Arg1291Gln Uncertain significance Single submitter
- NUMA1 p.Arg1298Gln Uncertain significance Single submitter
- NUMA1 p.Arg1305Gln Uncertain significance Single submitter
- NUMA1 p.Arg1312Gln Uncertain significance Single submitter
- NUMA1 p.Arg1490His Uncertain significance Single submitter
- NUMA1 p.Arg1503Gln Uncertain significance Single submitter
- NUMA1 p.Arg1649Gln Uncertain significance Single submitter
- NUMA1 p.Arg1710His Uncertain significance Single submitter
- NUMA1 p.Arg1743Cys Uncertain significance Single submitter
- NUMA1 p.Arg1743His Uncertain significance Single submitter
- NUMA1 p.Arg1781Trp Uncertain significance Single submitter
- NUMA1 p.Arg1802Gly Uncertain significance Single submitter
- NUMA1 p.Arg1808His Uncertain significance Single submitter
- NUMA1 p.Arg180His Uncertain significance Single submitter
- NUMA1 p.Arg1839Trp Uncertain significance Single submitter
- NUMA1 p.Arg1928Gln Uncertain significance Single submitter
- NUMA1 p.Arg1966Cys Uncertain significance Single submitter
- NUMA1 p.Arg1987His Uncertain significance Single submitter
- NUMA1 p.Arg2017Gln Uncertain significance Single submitter
- NUMA1 p.Arg2044Gln Uncertain significance Single submitter
- NUMA1 p.Arg2065Gln Uncertain significance Single submitter
- NUMA1 p.Arg2065Trp Uncertain significance Single submitter
- NUMA1 p.Arg2081His Uncertain significance Single submitter
- NUMA1 p.Arg2086Cys Uncertain significance Single submitter
- NUMA1 p.Arg2086His Uncertain significance Single submitter
- NUMA1 p.Arg2089His Uncertain significance Single submitter
- NUMA1 p.Arg592Gln Uncertain significance Single submitter
- NUMA1 p.Arg663Leu Uncertain significance Single submitter
- NUMA1 p.Arg723His Uncertain significance Single submitter
- NUMA1 p.Arg734His Uncertain significance Single submitter
- NUMA1 p.Arg744Gln Uncertain significance Single submitter
- NUMA1 p.Arg752Gly Uncertain significance Single submitter
- NUMA1 p.Arg846His Uncertain significance Single submitter
- NUMA1 p.Arg869Gln Uncertain significance Single submitter
- NUMA1 p.Arg935Trp Uncertain significance Single submitter
- NUMA1 p.Arg958His Uncertain significance Single submitter
- NUMA1 p.Arg983Gln Uncertain significance Single submitter
- NUMA1 p.Asn16Asp Uncertain significance Single submitter
- NUMA1 p.Asn1832Ser Uncertain significance Single submitter
- NUMA1 p.Asn1867Ser Uncertain significance Single submitter
- NUMA1 p.Asn1918Ser Uncertain significance Single submitter
- NUMA1 p.Asn2054Ser Uncertain significance Single submitter
- NUMA1 p.Asn342Ser Uncertain significance Single submitter
- NUMA1 p.Asn880Thr Uncertain significance Single submitter
- NUMA1 p.Asp1791Gly Uncertain significance Single submitter
- NUMA1 p.Asp1824Glu Uncertain significance Single submitter
- NUMA1 p.Asp1864Asn Uncertain significance Single submitter
- NUMA1 p.Asp632Asn Uncertain significance Single submitter
- NUMA1 p.Asp946Asn Uncertain significance Single submitter
- NUMA1 p.Cys160Trp Uncertain significance Single submitter
- NUMA1 p.Cys735Arg Uncertain significance Single submitter
- NUMA1 p.Gln1035Arg Uncertain significance Single submitter
- NUMA1 p.Gln1041Glu Uncertain significance Single submitter
- NUMA1 p.Gln1140Arg Uncertain significance Single submitter
- NUMA1 p.Gln1354Glu Uncertain significance Single submitter
- NUMA1 p.Gln1679Glu Uncertain significance Single submitter
- NUMA1 p.Gln1692Glu Uncertain significance Single submitter
- NUMA1 p.Gln1745Arg Uncertain significance Single submitter
- NUMA1 p.Gln1761Glu Uncertain significance Single submitter
- NUMA1 p.Gln1888His Uncertain significance Single submitter
- NUMA1 p.Gln1985Arg Uncertain significance Single submitter
- NUMA1 p.Gln463His Uncertain significance Single submitter
- NUMA1 p.Gln541Arg Uncertain significance Single submitter
- NUMA1 p.Gln623Arg Uncertain significance Single submitter
- NUMA1 p.Gln670Arg Uncertain significance Single submitter
- NUMA1 p.Gln796His Uncertain significance Single submitter
- NUMA1 p.Gln826Pro Uncertain significance Single submitter
- NUMA1 p.Gln906Arg Uncertain significance Single submitter
- NUMA1 p.Gln968Arg Uncertain significance Single submitter
- NUMA1 p.Glu1123Gly Uncertain significance Single submitter
- NUMA1 p.Glu1398Asp Uncertain significance Single submitter
- NUMA1 p.Glu1504Gln Uncertain significance Single submitter
- NUMA1 p.Glu1546Gln Uncertain significance Single submitter
- NUMA1 p.Glu1595Asp Uncertain significance Single submitter
- NUMA1 p.Glu1827Val Uncertain significance Single submitter
- NUMA1 p.Glu1977Asp Uncertain significance Single submitter
- NUMA1 p.Glu363Lys Uncertain significance Single submitter
- NUMA1 p.Glu381Lys Uncertain significance Single submitter
- NUMA1 p.Glu677Gln Uncertain significance Single submitter
- NUMA1 p.Glu720Lys Uncertain significance Single submitter
- NUMA1 p.Glu753Lys Uncertain significance Single submitter
- NUMA1 p.Glu781Asp Uncertain significance Single submitter
- NUMA1 p.Glu802Asp Uncertain significance Single submitter
- NUMA1 p.Glu833Gly Uncertain significance Single submitter
- NUMA1 p.Glu876Lys Uncertain significance Single submitter
- NUMA1 p.Glu92Gln Uncertain significance Single submitter
- NUMA1 p.Glu931Gln Uncertain significance Single submitter
- NUMA1 p.Glu950Lys Uncertain significance Single submitter
- NUMA1 p.Glu954Asp Uncertain significance Single submitter
- NUMA1 p.Gly1514Ser Uncertain significance Single submitter
- NUMA1 p.Gly1801Ser Uncertain significance Single submitter
- NUMA1 p.Gly1905Ser Uncertain significance Single submitter
- NUMA1 p.Gly2022Arg Uncertain significance Single submitter
- NUMA1 p.Gly410Ser Uncertain significance Single submitter
- NUMA1 p.Gly455Val Uncertain significance Single submitter
- NUMA1 p.Gly858Val Uncertain significance Single submitter
- NUMA1 p.His105Gln Uncertain significance Single submitter
- NUMA1 p.His1202Asn Uncertain significance Single submitter
- NUMA1 p.His1609Tyr Uncertain significance Single submitter
- NUMA1 p.His173Tyr Uncertain significance Single submitter
- NUMA1 p.His551Arg Uncertain significance Single submitter
- NUMA1 p.His778Tyr Uncertain significance Single submitter
- NUMA1 p.His797Gln Uncertain significance Single submitter
- NUMA1 p.Ile1722Thr Uncertain significance Single submitter
- NUMA1 p.Ile1737Val Uncertain significance Single submitter
- NUMA1 p.Ile43Met Uncertain significance Single submitter
- NUMA1 p.Ile619Thr Uncertain significance Single submitter
- NUMA1 p.Ile736Val Uncertain significance Single submitter
- NUMA1 p.Leu1269Met Uncertain significance Single submitter
- NUMA1 p.Leu1348Phe Uncertain significance Single submitter
- NUMA1 p.Leu1356Met Uncertain significance Single submitter
- NUMA1 p.Leu1370Val Uncertain significance Single submitter
Predictors split 64
The independent predictors disagree with each other — read with care.
- NUMA1 p.Arg1885Cys Uncertain significance Multiple submitters
- NUMA1 p.Ala545Pro Uncertain significance Single submitter
- NUMA1 p.Arg1084Trp Uncertain significance Single submitter
- NUMA1 p.Arg1160Trp Uncertain significance Single submitter
- NUMA1 p.Arg1217Trp Uncertain significance Single submitter
- NUMA1 p.Arg1253Trp Uncertain significance Single submitter
- NUMA1 p.Arg1452Trp Uncertain significance Single submitter
- NUMA1 p.Arg1462Trp Uncertain significance Single submitter
- NUMA1 p.Arg1588Cys Uncertain significance Single submitter
- NUMA1 p.Arg1588His Uncertain significance Single submitter
- NUMA1 p.Arg1805Cys Uncertain significance Single submitter
- NUMA1 p.Arg1808Cys Uncertain significance Single submitter
- NUMA1 p.Arg1809Trp Uncertain significance Single submitter
- NUMA1 p.Arg1810His Uncertain significance Single submitter
- NUMA1 p.Arg1877His Uncertain significance Single submitter
- NUMA1 p.Arg1881Cys Uncertain significance Single submitter
- NUMA1 p.Arg1885His Likely benign Single submitter
- NUMA1 p.Arg1919Cys Uncertain significance Single submitter
- NUMA1 p.Arg1926His Uncertain significance Single submitter
- NUMA1 p.Arg1987Cys Likely benign Single submitter
- NUMA1 p.Arg2012His Uncertain significance Single submitter
- NUMA1 p.Arg2044Trp Uncertain significance Single submitter
- NUMA1 p.Arg2045His Uncertain significance Single submitter
- NUMA1 p.Arg495Trp Uncertain significance Single submitter
- NUMA1 p.Arg599Gln Uncertain significance Single submitter
- NUMA1 p.Arg631Trp Uncertain significance Single submitter
- NUMA1 p.Arg643Trp Uncertain significance Single submitter
- NUMA1 p.Arg681Trp Uncertain significance Single submitter
- NUMA1 p.Arg752Trp Uncertain significance Single submitter
- NUMA1 p.Arg764Cys Uncertain significance Single submitter
- NUMA1 p.Arg7Pro Uncertain significance Single submitter
- NUMA1 p.Arg869Trp Uncertain significance Single submitter
- NUMA1 p.Arg918Cys Likely benign Single submitter
- NUMA1 p.Arg983Trp Uncertain significance Single submitter
- NUMA1 p.Arg999His Uncertain significance Single submitter
- NUMA1 p.Asn1039Lys Uncertain significance Single submitter
- NUMA1 p.Asn1816Ile Uncertain significance Single submitter
- NUMA1 p.Asp1691Ala Uncertain significance Single submitter
- NUMA1 p.Gln1693His Uncertain significance Single submitter
- NUMA1 p.Gln685Pro Uncertain significance Single submitter
- NUMA1 p.Glu1910Lys Uncertain significance Single submitter
- NUMA1 p.Glu319Lys Uncertain significance Single submitter
- NUMA1 p.Glu644Lys Uncertain significance Single submitter
- NUMA1 p.Gly385Arg Uncertain significance Single submitter
- NUMA1 p.Ile1817Thr Uncertain significance Single submitter
- NUMA1 p.Ile2090Thr Uncertain significance Single submitter
- NUMA1 p.Leu1090Met Uncertain significance Single submitter
- NUMA1 p.Leu1727Pro Uncertain significance Single submitter
- NUMA1 p.Leu1773Phe Conflicting Single submitter
- NUMA1 p.Leu61Gln Uncertain significance Single submitter
- NUMA1 p.Leu704Phe Uncertain significance Single submitter
- NUMA1 p.Leu785Arg Uncertain significance Single submitter
- NUMA1 p.Met1614Thr Uncertain significance Single submitter
- NUMA1 p.Pro2088Leu Uncertain significance Single submitter
- NUMA1 p.Pro56Leu Uncertain significance Single submitter
- NUMA1 p.Ser1834Trp Uncertain significance Single submitter
- NUMA1 p.Ser2047Leu Likely benign Single submitter
- NUMA1 p.Ser2074Tyr Uncertain significance Single submitter
- NUMA1 p.Ser476Pro Uncertain significance Single submitter
- NUMA1 p.Thr1677Ile Uncertain significance Single submitter
- NUMA1 p.Tyr1610Cys Uncertain significance Single submitter
- NUMA1 p.Tyr1938Cys Uncertain significance Single submitter
- NUMA1 p.Val57Met Uncertain significance Single submitter
-
NUMA1 p.Arg1239Pro
Pathogenic
No assertion criteria
myoepithelial tumor
All NUMA1 variants
Pathogenic 1
- p.Arg1239Pro No assertion criteria myoepithelial tumor ⚠
Conflicting classifications of pathogenicity 3
- p.Arg1762Cys Single submitter ⚠
- p.Leu1773Phe Single submitter ⚠
- p.Thr345Ser Single submitter ⚠
Benign 12
- p.Ala1443= Multiple submitters
- p.Arg443Gln Multiple submitters
- p.Arg972Gln Multiple submitters
- p.Leu1272= Multiple submitters
- p.Ser1800= Multiple submitters
- p.Val1825Met Multiple submitters
- p.Ala1051Val Single submitter
- p.Gln1135His Single submitter
- p.Glu809Asp Single submitter
- p.Met108Ile Single submitter
- p.Ser1105Pro Single submitter
- p.Gly978Ser No assertion criteria NUMA1-related disorder
Benign/Likely benign 3
- p.Arg1762His Multiple submitters acute promyelocytic leukemia
- p.Asn979= Multiple submitters acute promyelocytic leukemia
- p.Asp1795Asn Multiple submitters
Likely benign 41
- p.Asn477Ser Multiple submitters
- p.Leu327= Multiple submitters
- p.Tyr1836His Multiple submitters
- p.Ala1257= Single submitter
- p.Ala368Thr Single submitter
- p.Ala726= Single submitter
- p.Arg1084Gln Single submitter
- p.Arg1154Gln Single submitter
- p.Arg1196His Single submitter
- p.Arg1217Gln Single submitter
- p.Arg1496Gln Single submitter
- p.Arg1808= Single submitter
- p.Arg1885His Single submitter ⚠
- p.Arg1987Cys Single submitter ⚠
- p.Arg681Gln Single submitter
- p.Arg787Gln Single submitter
- p.Arg918Cys Single submitter ⚠
- p.Asn880Ser Single submitter
- p.Gly1894= Single submitter
- p.Gly455Asp Single submitter
- p.Leu1315Val Single submitter
- p.Ser2047Leu Single submitter ⚠
- p.Ser502Cys Single submitter
- p.Ser58Pro Single submitter
- p.Thr1057Met Single submitter
- p.Thr1851Ala Single submitter
- p.Thr2080= Single submitter
- c.4840-8G>A No assertion criteria NUMA1-related disorder
- c.6336+3AG[3] No assertion criteria NUMA1-related disorder
- p.Asp139= No assertion criteria NUMA1-related disorder
- p.Asp1795= No assertion criteria NUMA1-related disorder
- p.Gln1263= No assertion criteria NUMA1-related disorder
- p.Glu1309= No assertion criteria NUMA1-related disorder
- p.Gly1580= No assertion criteria NUMA1-related disorder
- p.Gly1980= No assertion criteria NUMA1-related disorder
- p.Gly828= No assertion criteria NUMA1-related disorder
- p.His581= No assertion criteria NUMA1-related disorder
- p.Leu1348= No assertion criteria NUMA1-related disorder
- p.Leu344Val No assertion criteria NUMA1-related disorder
- p.Thr2093= No assertion criteria NUMA1-related disorder
- p.Thr6= No assertion criteria NUMA1-related disorder
Uncertain significance 266
- p.Arg1885Cys Multiple submitters ⚠
- p.Ala1075Ser Single submitter ⚠
- p.Ala10Val Single submitter ⚠
- p.Ala1102Thr Single submitter ⚠
- p.Ala1124Thr Single submitter ⚠
- p.Ala1152Val Single submitter ⚠
- p.Ala1220Gly Single submitter ⚠
- p.Ala1319Thr Single submitter ⚠
- p.Ala1331Val Single submitter ⚠
- p.Ala1376Thr Single submitter ⚠
- p.Ala1392Thr Single submitter ⚠
- p.Ala1510Val Single submitter ⚠
- p.Ala1574Asp Single submitter ⚠
- p.Ala1714Pro Single submitter ⚠
- p.Ala1807fs Single submitter
- p.Ala1807Thr Single submitter ⚠
- p.Ala1843Pro Single submitter ⚠
- p.Ala2006Val Single submitter ⚠
- p.Ala2102Thr Single submitter ⚠
- p.Ala340Val Single submitter ⚠
- p.Ala426Thr Single submitter ⚠
- p.Ala488Thr Single submitter ⚠
- p.Ala545Pro Single submitter ⚠
- p.Ala571Val Single submitter ⚠
- p.Ala582Thr Single submitter ⚠
- p.Ala594Val Single submitter ⚠
- p.Ala5Val Single submitter ⚠
- p.Ala646Gly Single submitter ⚠
- p.Ala769Val Single submitter ⚠
- p.Ala812Gly Single submitter ⚠
- p.Ala9Thr Single submitter ⚠
- p.Arg1033Gln Single submitter ⚠
- p.Arg1033Trp Single submitter ⚠
- p.Arg1084Trp Single submitter ⚠
- p.Arg1126Trp Single submitter ⚠
- p.Arg1148Cys Single submitter ⚠
- p.Arg1157Trp Single submitter ⚠
- p.Arg1160Trp Single submitter ⚠
- p.Arg1190Gln Single submitter ⚠
- p.Arg1196Cys Single submitter ⚠
- p.Arg1217Trp Single submitter ⚠
- p.Arg1239Cys Single submitter ⚠
- p.Arg1239His Single submitter ⚠
- p.Arg1253Trp Single submitter ⚠
- p.Arg1282Lys Single submitter ⚠
- p.Arg1291Gln Single submitter ⚠
- p.Arg1298Gln Single submitter ⚠
- p.Arg1305Gln Single submitter ⚠
- p.Arg1312Gln Single submitter ⚠
- p.Arg1452Trp Single submitter ⚠
- p.Arg1462Trp Single submitter ⚠
- p.Arg1490His Single submitter ⚠
- p.Arg1503Gln Single submitter ⚠
- p.Arg1588Cys Single submitter ⚠
- p.Arg1588His Single submitter ⚠
- p.Arg1649Gln Single submitter ⚠
- p.Arg1710His Single submitter ⚠
- p.Arg1743Cys Single submitter ⚠
- p.Arg1743His Single submitter ⚠
- p.Arg1781Trp Single submitter ⚠
- p.Arg1802Gly Single submitter ⚠
- p.Arg1805Cys Single submitter ⚠
- p.Arg1808Cys Single submitter ⚠
- p.Arg1808His Single submitter ⚠
- p.Arg1809Trp Single submitter ⚠
- p.Arg180His Single submitter ⚠
- p.Arg1810His Single submitter ⚠
- p.Arg1839Trp Single submitter ⚠
- p.Arg1877His Single submitter ⚠
- p.Arg1881Cys Single submitter ⚠
- p.Arg1919Cys Single submitter ⚠
- p.Arg1926His Single submitter ⚠
- p.Arg1928Gln Single submitter ⚠
- p.Arg1966Cys Single submitter ⚠
- p.Arg1987His Single submitter ⚠
- p.Arg1989Gln Single submitter
- p.Arg2012His Single submitter ⚠
- p.Arg2017Gln Single submitter ⚠
- p.Arg2044Gln Single submitter ⚠
- p.Arg2044Trp Single submitter ⚠
- p.Arg2045His Single submitter ⚠
- p.Arg2065Gln Single submitter ⚠
- p.Arg2065Trp Single submitter ⚠
- p.Arg2081His Single submitter ⚠
- p.Arg2086Cys Single submitter ⚠
- p.Arg2086His Single submitter ⚠
- p.Arg2089His Single submitter ⚠
- p.Arg495Trp Single submitter ⚠
- p.Arg592Gln Single submitter ⚠
- p.Arg599Gln Single submitter ⚠
- p.Arg631Trp Single submitter ⚠
- p.Arg643Trp Single submitter ⚠
- p.Arg663Leu Single submitter ⚠
- p.Arg681Trp Single submitter ⚠
- p.Arg723His Single submitter ⚠
- p.Arg734His Single submitter ⚠
- p.Arg744Gln Single submitter ⚠
- p.Arg752Gly Single submitter ⚠
- p.Arg752Trp Single submitter ⚠
- p.Arg754Ter Single submitter
- p.Arg764Cys Single submitter ⚠
- p.Arg7Pro Single submitter ⚠
- p.Arg846His Single submitter ⚠
- p.Arg869Gln Single submitter ⚠
- p.Arg869Trp Single submitter ⚠
- p.Arg935Trp Single submitter ⚠
- p.Arg958His Single submitter ⚠
- p.Arg983Gln Single submitter ⚠
- p.Arg983Trp Single submitter ⚠
- p.Arg999His Single submitter ⚠
- p.Asn1039Lys Single submitter ⚠
- p.Asn16Asp Single submitter ⚠
- p.Asn1816Ile Single submitter ⚠
- p.Asn1832Ser Single submitter ⚠
- p.Asn1867Ser Single submitter ⚠
- p.Asn1918Ser Single submitter ⚠
- p.Asn2054Ser Single submitter ⚠
- p.Asn342Ser Single submitter ⚠
- p.Asn880Thr Single submitter ⚠
- p.Asp1691Ala Single submitter ⚠
- p.Asp1791Gly Single submitter ⚠
- p.Asp1824Glu Single submitter ⚠
- p.Asp1864Asn Single submitter ⚠
- p.Asp632Asn Single submitter ⚠
- p.Asp946Asn Single submitter ⚠
- p.Cys160Trp Single submitter ⚠
- p.Cys735Arg Single submitter ⚠
- p.Gln1035Arg Single submitter ⚠
- p.Gln1041Glu Single submitter ⚠
- p.Gln1049Ter Single submitter
- p.Gln1140Arg Single submitter ⚠
- p.Gln1354Glu Single submitter ⚠
- p.Gln1584fs Single submitter
- p.Gln1679Glu Single submitter ⚠
- p.Gln1692Glu Single submitter ⚠
- p.Gln1693His Single submitter ⚠
- p.Gln1745Arg Single submitter ⚠
- p.Gln1761Glu Single submitter ⚠
- p.Gln1888His Single submitter ⚠
- p.Gln1985Arg Single submitter ⚠
- p.Gln463His Single submitter ⚠
- p.Gln541Arg Single submitter ⚠
- p.Gln623Arg Single submitter ⚠
- p.Gln670Arg Single submitter ⚠
- p.Gln685Pro Single submitter ⚠
- p.Gln796His Single submitter ⚠
- p.Gln826Pro Single submitter ⚠
- p.Gln906Arg Single submitter ⚠
- p.Gln968Arg Single submitter ⚠
- p.Glu1123Gly Single submitter ⚠
- p.Glu1398Asp Single submitter ⚠
- p.Glu1504Gln Single submitter ⚠
- p.Glu1546Gln Single submitter ⚠
- p.Glu1595Asp Single submitter ⚠
- p.Glu1827Val Single submitter ⚠
- p.Glu1910Lys Single submitter ⚠
- p.Glu1977Asp Single submitter ⚠
- p.Glu319Lys Single submitter ⚠
- p.Glu363Lys Single submitter ⚠
- p.Glu381Lys Single submitter ⚠
- p.Glu644Lys Single submitter ⚠
- p.Glu677Gln Single submitter ⚠
- p.Glu720Lys Single submitter ⚠
- p.Glu753Lys Single submitter ⚠
- p.Glu781Asp Single submitter ⚠
- p.Glu802Asp Single submitter ⚠
- p.Glu833Gly Single submitter ⚠
- p.Glu876Lys Single submitter ⚠
- p.Glu92Gln Single submitter ⚠
- p.Glu931Gln Single submitter ⚠
- p.Glu950Lys Single submitter ⚠
- p.Glu954Asp Single submitter ⚠
- p.Gly1514Ser Single submitter ⚠
- p.Gly1801Ser Single submitter ⚠
- p.Gly1905Ser Single submitter ⚠
- p.Gly2022Arg Single submitter ⚠
- p.Gly385Arg Single submitter ⚠
- p.Gly410Ser Single submitter ⚠
- p.Gly455Val Single submitter ⚠
- p.Gly858Val Single submitter ⚠
- p.His105Gln Single submitter ⚠
- p.His1202Asn Single submitter ⚠
- p.His1609Tyr Single submitter ⚠
- p.His173Tyr Single submitter ⚠
- p.His551Arg Single submitter ⚠
- p.His778Tyr Single submitter ⚠
- p.His797Gln Single submitter ⚠
- p.Ile1722Thr Single submitter ⚠
- p.Ile1737Val Single submitter ⚠
- p.Ile1817Thr Single submitter ⚠
- p.Ile2090Thr Single submitter ⚠
- p.Ile43Met Single submitter ⚠
- p.Ile619Thr Single submitter ⚠
- p.Ile736Val Single submitter ⚠
- p.Leu1090Met Single submitter ⚠
- p.Leu1269Met Single submitter ⚠
- p.Leu1348Phe Single submitter ⚠
- p.Leu1356Met Single submitter ⚠
- p.Leu1370Val Single submitter ⚠
- p.Leu141Val Single submitter ⚠
- p.Leu1460Ile Single submitter ⚠
- p.Leu1727Pro Single submitter ⚠
- p.Leu1790Val Single submitter ⚠
- p.Leu1934Met Single submitter
- p.Leu61Gln Single submitter ⚠
- p.Leu704Phe Single submitter ⚠
- p.Leu785Arg Single submitter ⚠
- p.Leu81Gln Single submitter ⚠
- p.Leu881Met Single submitter ⚠
- p.Lys1430Glu Single submitter ⚠
- p.Lys1430Thr Single submitter ⚠
- p.Lys1549Thr Single submitter ⚠
- p.Lys1571Gln Single submitter ⚠
- p.Lys1616Arg Single submitter ⚠
- p.Lys2040Glu Single submitter ⚠
- p.Lys419Arg Single submitter ⚠
- p.Met1614Thr Single submitter ⚠
- p.Met2048Thr Single submitter ⚠
- p.Met793Leu Single submitter ⚠
- p.Met836Thr Single submitter ⚠
- p.Met989Thr Single submitter ⚠
- p.Phe164Leu Single submitter ⚠
- p.Phe164Tyr Single submitter ⚠
- p.Phe1835fs Single submitter
- p.Phe457Cys Single submitter ⚠
- p.Pro170Ser Single submitter ⚠
- p.Pro1764Leu Single submitter ⚠
- p.Pro1765Arg Single submitter ⚠
- p.Pro1765His Single submitter ⚠
- p.Pro1785Ser Single submitter ⚠
- p.Pro2088Leu Single submitter ⚠
- p.Pro401Leu Single submitter ⚠
- p.Pro56Leu Single submitter ⚠
- p.Ser1187Ala Single submitter ⚠
- p.Ser1187Leu Single submitter ⚠
- p.Ser1280Cys Single submitter ⚠
- p.Ser1308Leu Single submitter ⚠
- p.Ser1358Asn Single submitter ⚠
- p.Ser1582Ile Single submitter ⚠
- p.Ser172Gly Single submitter ⚠
- p.Ser1834Trp Single submitter ⚠
- p.Ser1837Thr Single submitter ⚠
- p.Ser1852Thr Single submitter ⚠
- p.Ser2003Cys Single submitter ⚠
- p.Ser2062Thr Single submitter ⚠
- p.Ser2074Tyr Single submitter ⚠
- p.Ser465Cys Single submitter ⚠
- p.Ser466Arg Single submitter ⚠
- p.Ser476Pro Single submitter ⚠
- p.Ser633Asn Single submitter ⚠
- p.Ser682Phe Single submitter ⚠
- p.Ser801Asn Single submitter ⚠
- p.Thr1677Ile Single submitter ⚠
- p.Thr2000Ile Single submitter ⚠
- p.Thr2084Ile Single submitter ⚠
- p.Thr345Ala Single submitter ⚠
- p.Tyr104His Single submitter ⚠
- p.Tyr1476His Single submitter ⚠
- p.Tyr1610Cys Single submitter ⚠
- p.Tyr1621Phe Single submitter ⚠
- p.Tyr1938Cys Single submitter ⚠
- p.Tyr817His Single submitter ⚠
- p.Val27Met Single submitter ⚠
- p.Val57Met Single submitter ⚠
- p.Val673Ala Single submitter ⚠
- p.Asn195Ser No assertion criteria ⚠