OR10J3 — 49 ClinVar variants
All ClinVar germline OR10J3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 43 flagged for review →
5 Likely benign · 44 Uncertain significance
Full OR10J3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 43
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 32
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- OR10J3 n.1005C>G Uncertain significance Single submitter
- OR10J3 n.1011G>A Uncertain significance Single submitter
- OR10J3 n.1025A>G Uncertain significance Single submitter
- OR10J3 n.1026A>T Uncertain significance Single submitter
- OR10J3 n.1032T>A Uncertain significance Single submitter
- OR10J3 n.1077T>G Uncertain significance Single submitter
- OR10J3 n.1083T>C Uncertain significance Single submitter
- OR10J3 n.171A>G Uncertain significance Single submitter
- OR10J3 n.251C>T Uncertain significance Single submitter
- OR10J3 n.318G>A Uncertain significance Single submitter
- OR10J3 n.324C>T Uncertain significance Single submitter
- OR10J3 n.344A>G Uncertain significance Single submitter
- OR10J3 n.347C>G Uncertain significance Single submitter
- OR10J3 n.356C>A Uncertain significance Single submitter
- OR10J3 n.590G>A Uncertain significance Single submitter
- OR10J3 n.615C>A Uncertain significance Single submitter
- OR10J3 n.632T>A Uncertain significance Single submitter
- OR10J3 n.651A>G Uncertain significance Single submitter
- OR10J3 n.652C>A Uncertain significance Single submitter
- OR10J3 n.713G>A Uncertain significance Single submitter
- OR10J3 n.713G>T Uncertain significance Single submitter
- OR10J3 n.758G>A Uncertain significance Single submitter
- OR10J3 n.818G>A Uncertain significance Single submitter
- OR10J3 n.837T>C Uncertain significance Single submitter
- OR10J3 n.923A>G Uncertain significance Single submitter
- OR10J3 n.941C>T Uncertain significance Single submitter
- OR10J3 n.945A>C Uncertain significance Single submitter
- OR10J3 n.956G>C Uncertain significance Single submitter
- OR10J3 n.962T>C Uncertain significance Single submitter
- OR10J3 n.962T>G Uncertain significance Single submitter
- OR10J3 n.966G>C Uncertain significance Single submitter
- OR10J3 n.975C>T Uncertain significance Single submitter
Predictors split 11
The independent predictors disagree with each other — read with care.
- OR10J3 n.119A>G Uncertain significance Single submitter
- OR10J3 n.299C>A Uncertain significance Single submitter
- OR10J3 n.345T>G Uncertain significance Single submitter
- OR10J3 n.356C>G Uncertain significance Single submitter
- OR10J3 n.410T>C Uncertain significance Single submitter
- OR10J3 n.468G>A Uncertain significance Single submitter
- OR10J3 n.494A>G Uncertain significance Single submitter
- OR10J3 n.513G>T Uncertain significance Single submitter
- OR10J3 n.764A>C Uncertain significance Single submitter
- OR10J3 n.780T>C Uncertain significance Single submitter
- OR10J3 n.855A>C Uncertain significance Single submitter
All OR10J3 variants
Likely benign 5
Uncertain significance 44
- n.1005C>G Single submitter ⚠
- n.1011G>A Single submitter ⚠
- n.1025A>G Single submitter ⚠
- n.1026A>T Single submitter ⚠
- n.1032T>A Single submitter ⚠
- n.1077T>G Single submitter ⚠
- n.1083T>C Single submitter ⚠
- n.119A>G Single submitter ⚠
- n.171A>G Single submitter ⚠
- n.251C>T Single submitter ⚠
- n.299C>A Single submitter ⚠
- n.303C>A Single submitter
- n.318G>A Single submitter ⚠
- n.324C>T Single submitter ⚠
- n.344A>G Single submitter ⚠
- n.345T>G Single submitter ⚠
- n.347C>G Single submitter ⚠
- n.356C>A Single submitter ⚠
- n.356C>G Single submitter ⚠
- n.410T>C Single submitter ⚠
- n.468G>A Single submitter ⚠
- n.494A>G Single submitter ⚠
- n.513G>T Single submitter ⚠
- n.590G>A Single submitter ⚠
- n.615C>A Single submitter ⚠
- n.632T>A Single submitter ⚠
- n.651A>G Single submitter ⚠
- n.652C>A Single submitter ⚠
- n.713G>A Single submitter ⚠
- n.713G>T Single submitter ⚠
- n.758G>A Single submitter ⚠
- n.764A>C Single submitter ⚠
- n.780T>C Single submitter ⚠
- n.818G>A Single submitter ⚠
- n.837T>C Single submitter ⚠
- n.855A>C Single submitter ⚠
- n.923A>G Single submitter ⚠
- n.941C>T Single submitter ⚠
- n.945A>C Single submitter ⚠
- n.956G>C Single submitter ⚠
- n.962T>C Single submitter ⚠
- n.962T>G Single submitter ⚠
- n.966G>C Single submitter ⚠
- n.975C>T Single submitter ⚠