PRRC2A — 458 ClinVar variants
All ClinVar germline PRRC2A variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 369 flagged for review →
41 Benign · 41 Likely benign · 376 Uncertain significance
Full PRRC2A gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 369
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 285
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 285
- PRRC2A p.Ala1006Val Uncertain significance Single submitter
- PRRC2A p.Ala1268Thr Uncertain significance Single submitter
- PRRC2A p.Ala1302Pro Uncertain significance Single submitter
- PRRC2A p.Ala1361Gly Uncertain significance Single submitter
- PRRC2A p.Ala1405Pro Uncertain significance Single submitter
- PRRC2A p.Ala1405Val Uncertain significance Single submitter
- PRRC2A p.Ala145Thr Uncertain significance Single submitter
- PRRC2A p.Ala1474Thr Uncertain significance Single submitter
- PRRC2A p.Ala1679Val Uncertain significance Single submitter
- PRRC2A p.Ala1787Val Uncertain significance Single submitter
- PRRC2A p.Ala1807Val Uncertain significance Single submitter
- PRRC2A p.Ala182Gly Uncertain significance Single submitter
- PRRC2A p.Ala183Ser Uncertain significance Single submitter
- PRRC2A p.Ala2022Val Uncertain significance Single submitter
- PRRC2A p.Ala286Val Uncertain significance Single submitter
- PRRC2A p.Ala37Thr Uncertain significance Single submitter
- PRRC2A p.Ala393Thr Uncertain significance Single submitter
- PRRC2A p.Ala420Ser Uncertain significance Single submitter
- PRRC2A p.Ala530Pro Uncertain significance Single submitter
- PRRC2A p.Ala949Thr Uncertain significance Single submitter
- PRRC2A p.Arg1010Gln Uncertain significance Single submitter
- PRRC2A p.Arg1010Trp Uncertain significance Single submitter
- PRRC2A p.Arg1047Gln Uncertain significance Single submitter
- PRRC2A p.Arg1055His Uncertain significance Single submitter
- PRRC2A p.Arg1061Gln Uncertain significance Single submitter
- PRRC2A p.Arg1066Cys Uncertain significance Single submitter
- PRRC2A p.Arg1080Gln Uncertain significance Single submitter
- PRRC2A p.Arg1156Gln Uncertain significance Single submitter
- PRRC2A p.Arg1239Gln Uncertain significance Single submitter
- PRRC2A p.Arg1264Gln Uncertain significance Single submitter
- PRRC2A p.Arg1300Cys Uncertain significance Single submitter
- PRRC2A p.Arg1300His Uncertain significance Single submitter
- PRRC2A p.Arg1301Gln Uncertain significance Single submitter
- PRRC2A p.Arg1301Pro Uncertain significance Single submitter
- PRRC2A p.Arg1370His Uncertain significance Single submitter
- PRRC2A p.Arg1439Gln Uncertain significance Single submitter
- PRRC2A p.Arg1446His Uncertain significance Single submitter
- PRRC2A p.Arg1446Ser Uncertain significance Single submitter
- PRRC2A p.Arg1486Cys Uncertain significance Single submitter
- PRRC2A p.Arg1541Lys Uncertain significance Single submitter
- PRRC2A p.Arg1561Gln Uncertain significance Single submitter
- PRRC2A p.Arg1566Gly Uncertain significance Single submitter
- PRRC2A p.Arg1613Cys Uncertain significance Single submitter
- PRRC2A p.Arg1620Gly Uncertain significance Single submitter
- PRRC2A p.Arg1709Ile Uncertain significance Single submitter
- PRRC2A p.Arg1755Gln Uncertain significance Single submitter
- PRRC2A p.Arg1755Gly Uncertain significance Single submitter
- PRRC2A p.Arg1772His Uncertain significance Single submitter
- PRRC2A p.Arg2032Gln Uncertain significance Single submitter
- PRRC2A p.Arg2047Gln Uncertain significance Single submitter
- PRRC2A p.Arg2075Gln Uncertain significance Single submitter
- PRRC2A p.Arg2102His Uncertain significance Single submitter
- PRRC2A p.Arg2105His Uncertain significance Single submitter
- PRRC2A p.Arg2119His Uncertain significance Single submitter
- PRRC2A p.Arg2127Pro Uncertain significance Single submitter
- PRRC2A p.Arg2133Leu Uncertain significance Single submitter
- PRRC2A p.Arg2139Trp Uncertain significance Single submitter
- PRRC2A p.Arg213Cys Uncertain significance Single submitter
- PRRC2A p.Arg213His Uncertain significance Single submitter
- PRRC2A p.Arg281Cys Uncertain significance Single submitter
- PRRC2A p.Arg281His Uncertain significance Single submitter
- PRRC2A p.Arg289Gln Uncertain significance Single submitter
- PRRC2A p.Arg296His Uncertain significance Single submitter
- PRRC2A p.Arg397Gln Uncertain significance Single submitter
- PRRC2A p.Arg417Gln Uncertain significance Single submitter
- PRRC2A p.Arg417Trp Uncertain significance Single submitter
- PRRC2A p.Arg432His Uncertain significance Single submitter
- PRRC2A p.Arg469Gln Uncertain significance Single submitter
- PRRC2A p.Arg503Gln Uncertain significance Single submitter
- PRRC2A p.Arg758His Uncertain significance Single submitter
- PRRC2A p.Arg771His Uncertain significance Single submitter
- PRRC2A p.Arg804His Uncertain significance Single submitter
- PRRC2A p.Arg853His Uncertain significance Single submitter
- PRRC2A p.Arg862His Uncertain significance Single submitter
- PRRC2A p.Arg917His Uncertain significance Single submitter
- PRRC2A p.Arg935His Uncertain significance Single submitter
- PRRC2A p.Arg947His Uncertain significance Single submitter
- PRRC2A p.Arg948Gln Uncertain significance Single submitter
- PRRC2A p.Asn1000His Uncertain significance Single submitter
- PRRC2A p.Asn1002Ile Uncertain significance Single submitter
- PRRC2A p.Asn203Ile Uncertain significance Single submitter
- PRRC2A p.Asp1768Asn Uncertain significance Single submitter
- PRRC2A p.Asp1798Tyr Uncertain significance Single submitter
- PRRC2A p.Asp351Glu Uncertain significance Single submitter
- PRRC2A p.Asp817Glu Uncertain significance Single submitter
- PRRC2A p.Asp973Val Uncertain significance Single submitter
- PRRC2A p.Gln1134Arg Uncertain significance Single submitter
- PRRC2A p.Gln1478Glu Uncertain significance Single submitter
- PRRC2A p.Gln1508Arg Uncertain significance Single submitter
- PRRC2A p.Gln1847Arg Uncertain significance Single submitter
- PRRC2A p.Gln320Arg Uncertain significance Single submitter
- PRRC2A p.Gln551Arg Uncertain significance Single submitter
- PRRC2A p.Glu1211Lys Uncertain significance Single submitter
- PRRC2A p.Glu1288Gln Uncertain significance Single submitter
- PRRC2A p.Glu1288Lys Uncertain significance Single submitter
- PRRC2A p.Glu1444Asp Uncertain significance Single submitter
- PRRC2A p.Glu1519Lys Uncertain significance Single submitter
- PRRC2A p.Glu1721Gly Uncertain significance Single submitter
- PRRC2A p.Glu1911Lys Uncertain significance Single submitter
- PRRC2A p.Glu2141Gly Uncertain significance Single submitter
- PRRC2A p.Glu507Asp Uncertain significance Single submitter
- PRRC2A p.Glu816Lys Uncertain significance Single submitter
- PRRC2A p.Glu857Gly Uncertain significance Single submitter
- PRRC2A p.Glu962Lys Uncertain significance Single submitter
- PRRC2A p.Glu970Lys Uncertain significance Single submitter
- PRRC2A p.Gly1027Cys Uncertain significance Single submitter
- PRRC2A p.Gly1072Arg Uncertain significance Single submitter
- PRRC2A p.Gly1130Arg Uncertain significance Single submitter
- PRRC2A p.Gly1224Arg Uncertain significance Single submitter
- PRRC2A p.Gly1364Asp Uncertain significance Single submitter
- PRRC2A p.Gly1403Ala Uncertain significance Single submitter
- PRRC2A p.Gly1494Arg Uncertain significance Single submitter
- PRRC2A p.Gly1495Ser Uncertain significance Single submitter
- PRRC2A p.Gly1526Ser Uncertain significance Single submitter
- PRRC2A p.Gly1602Ser Uncertain significance Single submitter
- PRRC2A p.Gly1703Ala Uncertain significance Single submitter
- PRRC2A p.Gly1744Ser Uncertain significance Single submitter
- PRRC2A p.Gly1851Glu Uncertain significance Single submitter
- PRRC2A p.Gly302Ser Uncertain significance Single submitter
- PRRC2A p.Gly354Ser Uncertain significance Single submitter
- PRRC2A p.Gly424Ala Uncertain significance Single submitter
- PRRC2A p.Gly434Asp Uncertain significance Single submitter
- PRRC2A p.Gly848Glu Uncertain significance Single submitter
- PRRC2A p.Gly907Arg Uncertain significance Single submitter
- PRRC2A p.Gly907Glu Uncertain significance Single submitter
- PRRC2A p.Gly989Glu Uncertain significance Single submitter
- PRRC2A p.Gly992Glu Uncertain significance Single submitter
- PRRC2A p.His1615Arg Uncertain significance Single submitter
- PRRC2A p.His1715Asn Uncertain significance Single submitter
- PRRC2A p.His1715Tyr Uncertain significance Single submitter
- PRRC2A p.His416Pro Uncertain significance Single submitter
- PRRC2A p.His662Tyr Uncertain significance Single submitter
- PRRC2A p.Leu1117Val Uncertain significance Single submitter
- PRRC2A p.Leu1309Val Uncertain significance Single submitter
- PRRC2A p.Leu1450Phe Uncertain significance Single submitter
- PRRC2A p.Leu1570Val Uncertain significance Single submitter
- PRRC2A p.Leu1585Phe Uncertain significance Single submitter
- PRRC2A p.Leu1785Pro Uncertain significance Single submitter
- PRRC2A p.Leu1897Pro Uncertain significance Single submitter
- PRRC2A p.Leu2090Arg Uncertain significance Single submitter
- PRRC2A p.Leu2108Phe Uncertain significance Single submitter
- PRRC2A p.Leu412Gln Uncertain significance Single submitter
- PRRC2A p.Leu528His Uncertain significance Single submitter
- PRRC2A p.Leu969Phe Uncertain significance Single submitter
- PRRC2A p.Lys1212Asn Uncertain significance Single submitter
- PRRC2A p.Lys1212Glu Uncertain significance Single submitter
- PRRC2A p.Lys1274Asn Uncertain significance Single submitter
- PRRC2A p.Lys1305Arg Uncertain significance Single submitter
- PRRC2A p.Lys1685Thr Uncertain significance Single submitter
- PRRC2A p.Lys224Arg Uncertain significance Single submitter
Predictors split 84
The independent predictors disagree with each other — read with care.
- PRRC2A p.Arg1028Gln Uncertain significance Single submitter
- PRRC2A p.Arg1039Gln Uncertain significance Single submitter
- PRRC2A p.Arg1039Trp Uncertain significance Single submitter
- PRRC2A p.Arg1045Gln Uncertain significance Single submitter
- PRRC2A p.Arg1052Trp Uncertain significance Single submitter
- PRRC2A p.Arg1055Cys Uncertain significance Single submitter
- PRRC2A p.Arg1058Leu Uncertain significance Single submitter
- PRRC2A p.Arg1061Gly Uncertain significance Single submitter
- PRRC2A p.Arg1088Gln Uncertain significance Single submitter
- PRRC2A p.Arg1088Gly Uncertain significance Single submitter
- PRRC2A p.Arg1101Cys Uncertain significance Single submitter
- PRRC2A p.Arg1152Cys Uncertain significance Single submitter
- PRRC2A p.Arg1152Ser Uncertain significance Single submitter
- PRRC2A p.Arg1170Gln Uncertain significance Single submitter
- PRRC2A p.Arg1170Trp Uncertain significance Single submitter
- PRRC2A p.Arg1244Gln Uncertain significance Single submitter
- PRRC2A p.Arg1258Gln Uncertain significance Single submitter
- PRRC2A p.Arg1376Ser Uncertain significance Single submitter
- PRRC2A p.Arg1394Trp Uncertain significance Single submitter
- PRRC2A p.Arg1398Cys Uncertain significance Single submitter
- PRRC2A p.Arg1431Ser Uncertain significance Single submitter
- PRRC2A p.Arg167Gly Uncertain significance Single submitter
- PRRC2A p.Arg1947Cys Uncertain significance Single submitter
- PRRC2A p.Arg1947Ser Uncertain significance Single submitter
- PRRC2A p.Arg2102Leu Uncertain significance Single submitter
- PRRC2A p.Arg284Cys Uncertain significance Single submitter
- PRRC2A p.Arg303His Uncertain significance Single submitter
- PRRC2A p.Arg450Gln Uncertain significance Single submitter
- PRRC2A p.Arg469Leu Uncertain significance Single submitter
- PRRC2A p.Arg483Trp Uncertain significance Single submitter
- PRRC2A p.Arg4Pro Uncertain significance Single submitter
- PRRC2A p.Arg649Gln Uncertain significance Single submitter
- PRRC2A p.Arg649Trp Uncertain significance Single submitter
- PRRC2A p.Arg722Gln Uncertain significance Single submitter
- PRRC2A p.Arg853Ser Uncertain significance Single submitter
- PRRC2A p.Arg925His Uncertain significance Single submitter
- PRRC2A p.Arg929His Uncertain significance Single submitter
- PRRC2A p.Arg947Ser Uncertain significance Single submitter
- PRRC2A p.Arg948Leu Uncertain significance Single submitter
- PRRC2A p.Arg948Trp Uncertain significance Single submitter
- PRRC2A p.Asn1313Ser Uncertain significance Single submitter
- PRRC2A p.Asp444Glu Uncertain significance Single submitter
- PRRC2A p.Asp731Asn Uncertain significance Single submitter
- PRRC2A p.Gln317His Uncertain significance Single submitter
- PRRC2A p.Gln650Arg Uncertain significance Single submitter
- PRRC2A p.Gln658His Uncertain significance Single submitter
- PRRC2A p.Glu1030Asp Uncertain significance Single submitter
- PRRC2A p.Glu1090Lys Uncertain significance Single submitter
- PRRC2A p.Glu1111Lys Uncertain significance Single submitter
- PRRC2A p.Glu473Asp Uncertain significance Single submitter
- PRRC2A p.Gly138Glu Uncertain significance Single submitter
- PRRC2A p.Gly1417Trp Uncertain significance Single submitter
- PRRC2A p.Gly1420Arg Uncertain significance Single submitter
- PRRC2A p.Gly1424Arg Uncertain significance Single submitter
- PRRC2A p.Gly1734Val Uncertain significance Single submitter
- PRRC2A p.Gly421Arg Uncertain significance Single submitter
- PRRC2A p.His662Pro Uncertain significance Single submitter
- PRRC2A p.His749Arg Uncertain significance Single submitter
- PRRC2A p.Ile1469Met Uncertain significance Single submitter
- PRRC2A p.Leu1892Pro Uncertain significance Single submitter
- PRRC2A p.Lys181Glu Uncertain significance Single submitter
- PRRC2A p.Lys66Arg Uncertain significance Single submitter
- PRRC2A p.Lys701Glu Uncertain significance Single submitter
- PRRC2A p.Lys788Asn Uncertain significance Single submitter
- PRRC2A p.Phe1901Leu Uncertain significance Single submitter
- PRRC2A p.Phe1933Leu Uncertain significance Single submitter
- PRRC2A p.Phe1993Val Uncertain significance Single submitter
- PRRC2A p.Phe261Cys Uncertain significance Single submitter
- PRRC2A p.Pro1307Ser Uncertain significance Single submitter
- PRRC2A p.Pro1390Ala Uncertain significance Single submitter
- PRRC2A p.Pro1390Leu Uncertain significance Single submitter
- PRRC2A p.Pro260Ser Uncertain significance Single submitter
- PRRC2A p.Ser1014Trp Uncertain significance Single submitter
- PRRC2A p.Ser1386Pro Uncertain significance Single submitter
- PRRC2A p.Ser1460Phe Uncertain significance Single submitter
- PRRC2A p.Ser146Arg Uncertain significance Single submitter
- PRRC2A p.Thr25Arg Uncertain significance Single submitter
- PRRC2A p.Trp1185Arg Uncertain significance Single submitter
- PRRC2A p.Trp2125Ser Uncertain significance Single submitter
- PRRC2A p.Trp791Arg Uncertain significance Single submitter
- PRRC2A p.Tyr1031Cys Uncertain significance Single submitter
- PRRC2A p.Tyr258Cys Uncertain significance Single submitter
- PRRC2A p.Val1166Met Uncertain significance Single submitter
-
PRRC2A p.Ser163Leu
Benign
No assertion criteria
PRRC2A-related disorder
All PRRC2A variants
Benign 41
- p.Arg804Cys Single submitter
- p.Gly1285Ala Single submitter
- p.Phe2083Ser Single submitter
- c.5624+9C>T No assertion criteria PRRC2A-related disorder
- p.508PAAP[1] No assertion criteria PRRC2A-related disorder
- p.Ala1283Thr No assertion criteria PRRC2A-related disorder
- p.Arg1036= No assertion criteria PRRC2A-related disorder
- p.Arg1370= No assertion criteria PRRC2A-related disorder
- p.Arg1563Gln No assertion criteria PRRC2A-related disorder
- p.Arg1740His No assertion criteria PRRC2A-related disorder
- p.Arg2075Trp No assertion criteria PRRC2A-related disorder
- p.Arg904= No assertion criteria PRRC2A-related disorder
- p.Asp1766Gly No assertion criteria PRRC2A-related disorder
- p.Gln1856= No assertion criteria PRRC2A-related disorder
- p.Gly1048= No assertion criteria PRRC2A-related disorder
- p.Gly1416Ser No assertion criteria PRRC2A-related disorder
- p.Gly1968= No assertion criteria PRRC2A-related disorder
- p.Gly212= No assertion criteria PRRC2A-related disorder
- p.Gly354= No assertion criteria PRRC2A-related disorder
- p.Gly793del No assertion criteria PRRC2A-related disorder
- p.Ile937Met No assertion criteria PRRC2A-related disorder
- p.Leu1503Pro No assertion criteria PRRC2A-related disorder
- p.Leu1895Val No assertion criteria PRRC2A-related disorder
- p.Leu1980Ile No assertion criteria PRRC2A-related disorder
- p.Pro106Leu No assertion criteria PRRC2A-related disorder
- p.Pro1883= No assertion criteria PRRC2A-related disorder
- p.Pro2006Ser No assertion criteria PRRC2A-related disorder
- p.Pro2057= No assertion criteria PRRC2A-related disorder
- p.Pro2130Leu No assertion criteria PRRC2A-related disorder
- p.Pro515Leu No assertion criteria PRRC2A-related disorder
- p.Pro559Ser No assertion criteria PRRC2A-related disorder
- p.Pro696= No assertion criteria PRRC2A-related disorder
- p.Pro698= No assertion criteria PRRC2A-related disorder
- p.Ser1219Tyr No assertion criteria PRRC2A-related disorder
- p.Ser1407Asn No assertion criteria PRRC2A-related disorder
- p.Ser163Leu No assertion criteria PRRC2A-related disorder ⚠
- p.Ser1808Phe No assertion criteria PRRC2A-related disorder
- p.Ser1905Pro No assertion criteria PRRC2A-related disorder
- p.Thr544Lys No assertion criteria PRRC2A-related disorder
- p.Val1774Met No assertion criteria PRRC2A-related disorder
- p.Val792= No assertion criteria PRRC2A-related disorder
Likely benign 41
- p.Ala420Thr Single submitter
- p.Ala565Pro Single submitter
- p.Ala798Thr Single submitter
- p.Arg1772Cys Single submitter
- p.Asn1000Ser Single submitter
- p.Asp1766= Single submitter
- p.Ile851Val Single submitter
- p.Leu528= Single submitter
- p.Met1853Ile Single submitter
- p.Met1983Val Single submitter
- p.Pro1194= Single submitter
- p.Pro885Thr Single submitter
- p.Ser365Ala Single submitter
- p.Ser932= Single submitter
- p.Thr1294Ala Single submitter
- p.Thr1906Ala Single submitter
- p.Thr1941Pro Single submitter
- p.Thr959Ala Single submitter
- p.Val2106Ile Single submitter
- c.391-6C>A No assertion criteria PRRC2A-related disorder
- c.4720-6C>G No assertion criteria PRRC2A-related disorder
- c.760-10C>G No assertion criteria PRRC2A-related disorder
- c.*9C>T No assertion criteria PRRC2A-related disorder
- p.Ala1222= No assertion criteria PRRC2A-related disorder
- p.Ala286= No assertion criteria PRRC2A-related disorder
- p.Ala814= No assertion criteria PRRC2A-related disorder
- p.Glu974Gln No assertion criteria PRRC2A-related disorder
- p.Leu493= No assertion criteria PRRC2A-related disorder
- p.Lys1677= No assertion criteria PRRC2A-related disorder
- p.Lys70= No assertion criteria PRRC2A-related disorder
- p.Phe1584= No assertion criteria PRRC2A-related disorder
- p.Pro1167= No assertion criteria PRRC2A-related disorder
- p.Pro1179del No assertion criteria PRRC2A-related disorder
- p.Pro1448= No assertion criteria PRRC2A-related disorder
- p.Pro1592= No assertion criteria PRRC2A-related disorder
- p.Pro1592Leu No assertion criteria PRRC2A-related disorder
- p.Pro1687Leu No assertion criteria PRRC2A-related disorder
- p.Pro74= No assertion criteria PRRC2A-related disorder
- p.Ser1952= No assertion criteria PRRC2A-related disorder
- p.Ser1954= No assertion criteria PRRC2A-related disorder
- p.Thr2093= No assertion criteria PRRC2A-related disorder
Uncertain significance 376
Showing the top 300 by review status; the full set is in the sitemap.
- c.6147_6147+1dup Single submitter
- c.983-2_983-1del Single submitter
- p.Ala1006Val Single submitter ⚠
- p.Ala1268Thr Single submitter ⚠
- p.Ala1302Pro Single submitter ⚠
- p.Ala1361Gly Single submitter ⚠
- p.Ala1405Pro Single submitter ⚠
- p.Ala1405Val Single submitter ⚠
- p.Ala145Thr Single submitter ⚠
- p.Ala1474Thr Single submitter ⚠
- p.Ala1679Val Single submitter ⚠
- p.Ala1787Val Single submitter ⚠
- p.Ala1807Val Single submitter ⚠
- p.Ala182Gly Single submitter ⚠
- p.Ala183Ser Single submitter ⚠
- p.Ala2022Val Single submitter ⚠
- p.Ala286Val Single submitter ⚠
- p.Ala37Thr Single submitter ⚠
- p.Ala393Thr Single submitter ⚠
- p.Ala420Ser Single submitter ⚠
- p.Ala530Pro Single submitter ⚠
- p.Ala949Thr Single submitter ⚠
- p.Arg1010Gln Single submitter ⚠
- p.Arg1010Trp Single submitter ⚠
- p.Arg1028Gln Single submitter ⚠
- p.Arg1039Gln Single submitter ⚠
- p.Arg1039Trp Single submitter ⚠
- p.Arg1045Gln Single submitter ⚠
- p.Arg1047Gln Single submitter ⚠
- p.Arg1052Trp Single submitter ⚠
- p.Arg1055Cys Single submitter ⚠
- p.Arg1055His Single submitter ⚠
- p.Arg1058Leu Single submitter ⚠
- p.Arg1061Gln Single submitter ⚠
- p.Arg1061Gly Single submitter ⚠
- p.Arg1066Cys Single submitter ⚠
- p.Arg1080Gln Single submitter ⚠
- p.Arg1088Gln Single submitter ⚠
- p.Arg1088Gly Single submitter ⚠
- p.Arg1101Cys Single submitter ⚠
- p.Arg1152Cys Single submitter ⚠
- p.Arg1152Ser Single submitter ⚠
- p.Arg1156Gln Single submitter ⚠
- p.Arg1170Gln Single submitter ⚠
- p.Arg1170Trp Single submitter ⚠
- p.Arg1239Gln Single submitter ⚠
- p.Arg1244Gln Single submitter ⚠
- p.Arg1258Gln Single submitter ⚠
- p.Arg1264Gln Single submitter ⚠
- p.Arg1300Cys Single submitter ⚠
- p.Arg1300His Single submitter ⚠
- p.Arg1301Gln Single submitter ⚠
- p.Arg1301Pro Single submitter ⚠
- p.Arg1370His Single submitter ⚠
- p.Arg1376Ser Single submitter ⚠
- p.Arg1394Trp Single submitter ⚠
- p.Arg1398Cys Single submitter ⚠
- p.Arg1431Ser Single submitter ⚠
- p.Arg1439Gln Single submitter ⚠
- p.Arg1439Ter Single submitter
- p.Arg1446His Single submitter ⚠
- p.Arg1446Ser Single submitter ⚠
- p.Arg1486Cys Single submitter ⚠
- p.Arg1541Lys Single submitter ⚠
- p.Arg1561Gln Single submitter ⚠
- p.Arg1566Gly Single submitter ⚠
- p.Arg1613Cys Single submitter ⚠
- p.Arg1620Gly Single submitter ⚠
- p.Arg167Gly Single submitter ⚠
- p.Arg1709Ile Single submitter ⚠
- p.Arg1755Gln Single submitter ⚠
- p.Arg1755Gly Single submitter ⚠
- p.Arg1772His Single submitter ⚠
- p.Arg1947Cys Single submitter ⚠
- p.Arg1947Ser Single submitter ⚠
- p.Arg200His Single submitter
- p.Arg2032Gln Single submitter ⚠
- p.Arg2047Gln Single submitter ⚠
- p.Arg2075Gln Single submitter ⚠
- p.Arg2102His Single submitter ⚠
- p.Arg2102Leu Single submitter ⚠
- p.Arg2105His Single submitter ⚠
- p.Arg2119His Single submitter ⚠
- p.Arg2127Pro Single submitter ⚠
- p.Arg2133Leu Single submitter ⚠
- p.Arg2139Trp Single submitter ⚠
- p.Arg213Cys Single submitter ⚠
- p.Arg213His Single submitter ⚠
- p.Arg281Cys Single submitter ⚠
- p.Arg281His Single submitter ⚠
- p.Arg284Cys Single submitter ⚠
- p.Arg289Gln Single submitter ⚠
- p.Arg296His Single submitter ⚠
- p.Arg303His Single submitter ⚠
- p.Arg397Gln Single submitter ⚠
- p.Arg417Gln Single submitter ⚠
- p.Arg417Trp Single submitter ⚠
- p.Arg432His Single submitter ⚠
- p.Arg450Gln Single submitter ⚠
- p.Arg469Gln Single submitter ⚠
- p.Arg469Leu Single submitter ⚠
- p.Arg483Trp Single submitter ⚠
- p.Arg4Pro Single submitter ⚠
- p.Arg503Gln Single submitter ⚠
- p.Arg649Gln Single submitter ⚠
- p.Arg649Trp Single submitter ⚠
- p.Arg722Gln Single submitter ⚠
- p.Arg758His Single submitter ⚠
- p.Arg771His Single submitter ⚠
- p.Arg804His Single submitter ⚠
- p.Arg853His Single submitter ⚠
- p.Arg853Ser Single submitter ⚠
- p.Arg862His Single submitter ⚠
- p.Arg917His Single submitter ⚠
- p.Arg925His Single submitter ⚠
- p.Arg929His Single submitter ⚠
- p.Arg935His Single submitter ⚠
- p.Arg947His Single submitter ⚠
- p.Arg947Ser Single submitter ⚠
- p.Arg948Gln Single submitter ⚠
- p.Arg948Leu Single submitter ⚠
- p.Arg948Trp Single submitter ⚠
- p.Asn1000His Single submitter ⚠
- p.Asn1002Ile Single submitter ⚠
- p.Asn1313Ser Single submitter ⚠
- p.Asn203Ile Single submitter ⚠
- p.Asp1768Asn Single submitter ⚠
- p.Asp1798Tyr Single submitter ⚠
- p.Asp351Glu Single submitter ⚠
- p.Asp444Glu Single submitter ⚠
- p.Asp731Asn Single submitter ⚠
- p.Asp817Glu Single submitter ⚠
- p.Asp973Val Single submitter ⚠
- p.Gln1134Arg Single submitter ⚠
- p.Gln1478Glu Single submitter ⚠
- p.Gln1508Arg Single submitter ⚠
- p.Gln1847Arg Single submitter ⚠
- p.Gln317His Single submitter ⚠
- p.Gln320Arg Single submitter ⚠
- p.Gln551Arg Single submitter ⚠
- p.Gln650Arg Single submitter ⚠
- p.Gln658His Single submitter ⚠
- p.Glu1030Asp Single submitter ⚠
- p.Glu1090Lys Single submitter ⚠
- p.Glu1111Lys Single submitter ⚠
- p.Glu1211Lys Single submitter ⚠
- p.Glu1288Gln Single submitter ⚠
- p.Glu1288Lys Single submitter ⚠
- p.Glu1444Asp Single submitter ⚠
- p.Glu1519Lys Single submitter ⚠
- p.Glu1721Gly Single submitter ⚠
- p.Glu1911Lys Single submitter ⚠
- p.Glu2141Gly Single submitter ⚠
- p.Glu473Asp Single submitter ⚠
- p.Glu507Asp Single submitter ⚠
- p.Glu816Lys Single submitter ⚠
- p.Glu857Gly Single submitter ⚠
- p.Glu962Lys Single submitter ⚠
- p.Glu970Lys Single submitter ⚠
- p.Gly1027Cys Single submitter ⚠
- p.Gly1072Arg Single submitter ⚠
- p.Gly1130Arg Single submitter ⚠
- p.Gly1224Arg Single submitter ⚠
- p.Gly1364Asp Single submitter ⚠
- p.Gly138Glu Single submitter ⚠
- p.Gly1403Ala Single submitter ⚠
- p.Gly1417Trp Single submitter ⚠
- p.Gly1420Arg Single submitter ⚠
- p.Gly1424Arg Single submitter ⚠
- p.Gly1494Arg Single submitter ⚠
- p.Gly1495Ser Single submitter ⚠
- p.Gly1526Ser Single submitter ⚠
- p.Gly1602Ser Single submitter ⚠
- p.Gly1703Ala Single submitter ⚠
- p.Gly1734Val Single submitter ⚠
- p.Gly1744Ser Single submitter ⚠
- p.Gly1851Glu Single submitter ⚠
- p.Gly302Ser Single submitter ⚠
- p.Gly354Ser Single submitter ⚠
- p.Gly421Arg Single submitter ⚠
- p.Gly424Ala Single submitter ⚠
- p.Gly434Asp Single submitter ⚠
- p.Gly848Glu Single submitter ⚠
- p.Gly907Arg Single submitter ⚠
- p.Gly907Glu Single submitter ⚠
- p.Gly989Glu Single submitter ⚠
- p.Gly992Glu Single submitter ⚠
- p.His1615Arg Single submitter ⚠
- p.His1715Asn Single submitter ⚠
- p.His1715Tyr Single submitter ⚠
- p.His416Pro Single submitter ⚠
- p.His662Pro Single submitter ⚠
- p.His662Tyr Single submitter ⚠
- p.His749Arg Single submitter ⚠
- p.Ile1469Met Single submitter ⚠
- p.Leu1117Val Single submitter ⚠
- p.Leu1279fs Single submitter
- p.Leu1309Val Single submitter ⚠
- p.Leu1450Phe Single submitter ⚠
- p.Leu1570Val Single submitter ⚠
- p.Leu1585Phe Single submitter ⚠
- p.Leu1785Pro Single submitter ⚠
- p.Leu1892Pro Single submitter ⚠
- p.Leu1897Pro Single submitter ⚠
- p.Leu2090Arg Single submitter ⚠
- p.Leu2108Phe Single submitter ⚠
- p.Leu412Gln Single submitter ⚠
- p.Leu528His Single submitter ⚠
- p.Leu969Phe Single submitter ⚠
- p.Lys1212Asn Single submitter ⚠
- p.Lys1212Glu Single submitter ⚠
- p.Lys1274Asn Single submitter ⚠
- p.Lys1305Arg Single submitter ⚠
- p.Lys1685Thr Single submitter ⚠
- p.Lys181Glu Single submitter ⚠
- p.Lys224Arg Single submitter ⚠
- p.Lys224Gln Single submitter ⚠
- p.Lys66Arg Single submitter ⚠
- p.Lys701Glu Single submitter ⚠
- p.Lys788Asn Single submitter ⚠
- p.Lys875Arg Single submitter ⚠
- p.Lys887Glu Single submitter ⚠
- p.Lys953Arg Single submitter ⚠
- p.Lys985Arg Single submitter ⚠
- p.Lys995Arg Single submitter ⚠
- p.Met1853Val Single submitter ⚠
- p.Met295Val Single submitter ⚠
- p.Met717Val Single submitter ⚠
- p.Phe1901Leu Single submitter ⚠
- p.Phe1933Leu Single submitter ⚠
- p.Phe1993Val Single submitter ⚠
- p.Phe261Cys Single submitter ⚠
- p.Pro105Leu Single submitter ⚠
- p.Pro1119Leu Single submitter ⚠
- p.Pro112Gln Single submitter ⚠
- p.Pro1136Ser Single submitter ⚠
- p.Pro1141Leu Single submitter ⚠
- p.Pro1177Ser Single submitter ⚠
- p.Pro1177Thr Single submitter ⚠
- p.Pro1178Leu Single submitter ⚠
- p.Pro1187Ser Single submitter ⚠
- p.Pro1197Ser Single submitter ⚠
- p.Pro1217Arg Single submitter ⚠
- p.Pro1217Leu Single submitter ⚠
- p.Pro1307Ser Single submitter ⚠
- p.Pro1342Ser Single submitter ⚠
- p.Pro1354Arg Single submitter ⚠
- p.Pro1390Ala Single submitter ⚠
- p.Pro1390Leu Single submitter ⚠
- p.Pro1401Thr Single submitter ⚠
- p.Pro1448Leu Single submitter ⚠
- p.Pro1456Leu Single submitter ⚠
- p.Pro1507Ser Single submitter ⚠
- p.Pro1512Thr Single submitter ⚠
- p.Pro1515Leu Single submitter ⚠
- p.Pro1520His Single submitter ⚠
- p.Pro1565Arg Single submitter ⚠
- p.Pro1592fs Single submitter
- p.Pro1594Arg Single submitter ⚠
- p.Pro1692His Single submitter ⚠
- p.Pro1706Arg Single submitter ⚠
- p.Pro1706Ser Single submitter ⚠
- p.Pro171Leu Single submitter ⚠
- p.Pro1843Leu Single submitter ⚠
- p.Pro1878Leu Single submitter ⚠
- p.Pro1931Leu Single submitter ⚠
- p.Pro1939Leu Single submitter ⚠
- p.Pro1960Ser Single submitter ⚠
- p.Pro1963Arg Single submitter ⚠
- p.Pro1982Ala Single submitter ⚠
- p.Pro1997Leu Single submitter ⚠
- p.Pro2002Ser Single submitter ⚠
- p.Pro2006Leu Single submitter ⚠
- p.Pro2014Leu Single submitter ⚠
- p.Pro2018Ser Single submitter ⚠
- p.Pro2037Ser Single submitter ⚠
- p.Pro2057Leu Single submitter ⚠
- p.Pro2143Leu Single submitter ⚠
- p.Pro2143Ser Single submitter ⚠
- p.Pro2156Leu Single submitter ⚠
- p.Pro231Leu Single submitter ⚠
- p.Pro231Ser Single submitter ⚠
- p.Pro241Leu Single submitter ⚠
- p.Pro260Ser Single submitter ⚠
- p.Pro262Leu Single submitter ⚠
- p.Pro279Arg Single submitter ⚠
- p.Pro279Leu Single submitter ⚠
- p.Pro294Gln Single submitter ⚠
- p.Pro371His Single submitter ⚠
- p.Pro386Leu Single submitter ⚠
- p.Pro403Leu Single submitter ⚠
- p.Pro405Leu Single submitter ⚠
- p.Pro410Ser Single submitter ⚠
- p.Pro413Ala Single submitter ⚠
- p.Pro413His Single submitter ⚠
- p.Pro414Ser Single submitter ⚠
- p.Pro440Ser Single submitter ⚠
- p.Pro500Ser Single submitter ⚠
- p.Pro515Ser Single submitter ⚠
- p.Pro518Leu Single submitter ⚠