PRRC2C — 332 ClinVar variants

All ClinVar germline PRRC2C variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.

21 Likely benign · 311 Uncertain significance

Full PRRC2C gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

All PRRC2C variants

Likely benign 21

p.Ala484= Single submitter
p.Asn1996Asp Single submitter
p.Asn2296Ser Single submitter
p.Asp890= Single submitter
p.Gln2403= Single submitter
p.Ile1895Val Single submitter
p.Ile800Val Single submitter
p.Ile962Thr Single submitter
p.Leu1474Val Single submitter
p.Leu906Val Single submitter
p.Pro1234= Single submitter
p.Pro1926Ser Single submitter
p.Pro706Gln Single submitter
p.Pro937Ala Single submitter
p.Ser192Thr Single submitter
p.Thr1598Ala Single submitter
p.Thr1783Ala Single submitter
p.Thr2497Ala Single submitter
p.Thr2856= Single submitter
p.Val1022= Single submitter
p.Val50= Single submitter

Uncertain significance 311

Showing the top 300 by review status; the full set is in the sitemap.

c.1055+2T>C Single submitter
p.Ala104Thr Single submitter
p.Ala1120Thr Single submitter
p.Ala1762Ser Single submitter
p.Ala1774Ser Single submitter
p.Ala1785Val Single submitter
p.Ala1927Thr Single submitter
p.Ala1930Val Single submitter
p.Ala1975Asp Single submitter
p.Ala2079Val Single submitter
p.Ala2095Val Single submitter
p.Ala2162Pro Single submitter
p.Ala2315Ser Single submitter
p.Ala240Thr Single submitter
p.Ala2580Thr Single submitter
p.Ala2625Pro Single submitter
p.Ala2632Thr Single submitter
p.Ala2644Ser Single submitter
p.Ala2817Thr Single submitter
p.Ala2890Val Single submitter
p.Ala290Val Single submitter
p.Ala317Val Single submitter
p.Ala799Thr Single submitter
p.Ala838Thr Single submitter
p.Ala891Gly Single submitter
p.Ala891Val Single submitter
p.Ala896Val Single submitter
p.Arg1154Gln Single submitter
p.Arg1200Gln Single submitter
p.Arg1214Ser Single submitter
p.Arg1218Gln Single submitter
p.Arg1247Gln Single submitter
p.Arg1247Trp Single submitter
p.Arg1352Cys Single submitter
p.Arg1352His Single submitter
p.Arg1360Cys Single submitter
p.Arg1363Cys Single submitter
p.Arg1373Gln Single submitter
p.Arg1373Trp Single submitter
p.Arg1421Ser Single submitter
p.Arg1511Gln Single submitter
p.Arg1538Thr Single submitter
p.Arg1553Cys Single submitter
p.Arg1556Gln Single submitter
p.Arg1701Gln Single submitter
p.Arg173His Single submitter
p.Arg2089Trp Single submitter
p.Arg2256Cys Single submitter
p.Arg2406Gln Single submitter
p.Arg2630His Single submitter
p.Arg2691Gly Single submitter
p.Arg2691Trp Single submitter
p.Arg295Cys Single submitter
p.Arg41Gln Single submitter
p.Arg468Cys Single submitter
p.Arg473Gln Single submitter
p.Arg479Thr Single submitter
p.Arg515Gln Single submitter
p.Arg515Trp Single submitter
p.Arg517His Single submitter
p.Arg571Trp Single submitter
p.Arg632Ile Single submitter
p.Arg637Cys Single submitter
p.Arg658Gln Single submitter
p.Arg658Trp Single submitter
p.Arg774Lys Single submitter
p.Arg806Cys Single submitter
p.Arg866Thr Single submitter
p.Arg879Ile Single submitter
p.Arg913Gln Single submitter
p.Arg923Gln Single submitter
p.Arg923Trp Single submitter
p.Arg954Gly Single submitter
p.Arg976Gln Single submitter
p.Arg994Cys Single submitter
p.Asn162Ser Single submitter
p.Asn1679Lys Single submitter
p.Asn1717His Single submitter
p.Asn2005Ser Single submitter
p.Asn2064Lys Single submitter
p.Asn2066Asp Single submitter
p.Asn213Ser Single submitter
p.Asn2261Ser Single submitter
p.Asn312Lys Single submitter
p.Asn312Ser Single submitter
p.Asn345Lys Single submitter
p.Asn72Ser Single submitter
p.Asp1281Glu Single submitter
p.Asp1484Asn Single submitter
p.Asp163Gly Single submitter
p.Asp1652Glu Single submitter
p.Asp1664Glu Single submitter
p.Asp1681Asn Single submitter
p.Asp196Val Single submitter
p.Asp2006Ala Single submitter
p.Asp2191Asn Single submitter
p.Asp2212Gly Single submitter
p.Asp491Asn Single submitter
p.Asp634His Single submitter
p.Asp833Asn Single submitter
p.Asp833Gly Single submitter
p.Asp863Asn Single submitter
p.Gln1126Glu Single submitter
p.Gln1185Pro Single submitter
p.Gln1376His Single submitter
p.Gln1743Leu Single submitter
p.Gln195Pro Single submitter
p.Gln202Arg Single submitter
p.Gln2088Arg Single submitter
p.Gln2233His Single submitter
p.Gln229Pro Single submitter
p.Gln2446His Single submitter
p.Gln2582Pro Single submitter
p.Gln2633Arg Single submitter
p.Gln2832Arg Single submitter
p.Gln380Arg Single submitter
p.Gln690Arg Single submitter
p.Gln700Arg Single submitter
p.Gln940Arg Single submitter
p.Glu1037Lys Single submitter
p.Glu1037Val Single submitter
p.Glu1046Gly Single submitter
p.Glu1275Gly Single submitter
p.Glu1383Val Single submitter
p.Glu1388Gly Single submitter
p.Glu1512Gln Single submitter
p.Glu2076Val Single submitter
p.Glu211Lys Single submitter
p.Glu2180Asp Single submitter
p.Glu303Val Single submitter
p.Glu462Gly Single submitter
p.Glu508Asp Single submitter
p.Glu514Lys Single submitter
p.Glu550Gly Single submitter
p.Glu556fs Single submitter
p.Glu556Lys Single submitter
p.Glu558Gln Single submitter
p.Glu588Gly Single submitter
p.Glu606Lys Single submitter
p.Glu614Gly Single submitter
p.Glu832Ala Single submitter
p.Gly1207Val Single submitter
p.Gly1212Val Single submitter
p.Gly132Val Single submitter
p.Gly1339Glu Single submitter
p.Gly134Val Single submitter
p.Gly1617Ser Single submitter
p.Gly184Asp Single submitter
p.Gly2140Glu Single submitter
p.Gly2489Ala Single submitter
p.Gly2509Ser Single submitter
p.Gly2537Ser Single submitter
p.Gly2599Arg Single submitter
p.Gly2838Glu Single submitter
p.Gly343fs Single submitter
p.Gly356Asp Single submitter
p.Gly356Val Single submitter
p.His1312Arg Single submitter
p.His1609Arg Single submitter
p.His2359Asn Single submitter
p.His2544Arg Single submitter
p.His407Arg Single submitter
p.His816fs Single submitter
p.His859Tyr Single submitter
p.His933Asn Single submitter
p.Ile1018Val Single submitter
p.Ile1402Val Single submitter
p.Ile1671Met Single submitter
p.Ile1980Val Single submitter
p.Ile2279Val Single submitter
p.Ile2492Val Single submitter
p.Ile2671Val Single submitter
p.Ile2876Val Single submitter
p.Ile2886Val Single submitter
p.Leu1148Val Single submitter
p.Leu1336Ile Single submitter
p.Leu1772Phe Single submitter
p.Leu2214Trp Single submitter
p.Leu2224Val Single submitter
p.Leu2535Ile Single submitter
p.Leu307Arg Single submitter
p.Leu408Val Single submitter
p.Leu414Ser Single submitter
p.Leu497Met Single submitter
p.Leu521Phe Single submitter
p.Lys1020Gln Single submitter
p.Lys1043Met Single submitter
p.Lys1122Arg Single submitter
p.Lys1135Arg Single submitter
p.Lys1174Glu Single submitter
p.Lys1290Glu Single submitter
p.Lys1298Glu Single submitter
p.Lys1406Gln Single submitter
p.Lys1516Glu Single submitter
p.Lys1583Glu Single submitter
p.Lys2081Glu Single submitter
p.Lys2228Glu Single submitter
p.Lys2268Thr Single submitter
p.Lys231Glu Single submitter
p.Lys367Glu Single submitter
p.Lys389Glu Single submitter
p.Lys413Glu Single submitter
p.Lys559Thr Single submitter
p.Lys575Arg Single submitter
p.Lys575Thr Single submitter
p.Lys587Glu Single submitter
p.Lys950Arg Single submitter
p.Lys950Asn Single submitter
p.Lys950Glu Single submitter
p.Met247Val Single submitter
p.Met258Leu Single submitter
p.Met557Thr Single submitter
p.Met723Val Single submitter
p.Met778Arg Single submitter
p.Phe1253Leu Single submitter
p.Phe1590Val Single submitter
p.Phe2392Leu Single submitter
p.Phe252Ile Single submitter
p.Phe2571Ile Single submitter
p.Phe2826Tyr Single submitter
p.Pro1062Ser Single submitter
p.Pro1064Arg Single submitter
p.Pro1067Leu Single submitter
p.Pro1072Leu Single submitter
p.Pro1090Leu Single submitter
p.Pro1153Ala Single submitter
p.Pro1155Ser Single submitter
p.Pro1169Ser Single submitter
p.Pro1183Arg Single submitter
p.Pro118Ser Single submitter
p.Pro1364Leu Single submitter
p.Pro1392Leu Single submitter
p.Pro1401Ala Single submitter
p.Pro1430Ser Single submitter
p.Pro1431Ala Single submitter
p.Pro1634Arg Single submitter
p.Pro1641Gln Single submitter
p.Pro1641Thr Single submitter
p.Pro168Leu Single submitter
p.Pro1750Ser Single submitter
p.Pro1786Leu Single submitter
p.Pro2016Leu Single submitter
p.Pro2097Ser Single submitter
p.Pro2108Leu Single submitter
p.Pro2227Ser Single submitter
p.Pro2453Ser Single submitter
p.Pro2614Ser Single submitter
p.Pro2615Leu Single submitter
p.Pro2689Leu Single submitter
p.Pro2851Ser Single submitter
p.Pro2852Ala Single submitter
p.Pro2870Leu Single submitter
p.Pro2871Leu Single submitter
p.Pro428Ser Single submitter
p.Pro431Thr Single submitter
p.Pro886Arg Single submitter
p.Ser1305Cys Single submitter
p.Ser1306Pro Single submitter
p.Ser1722Asn Single submitter
p.Ser1884Phe Single submitter
p.Ser1922Leu Single submitter
p.Ser1950Phe Single submitter
p.Ser205Asn Single submitter
p.Ser2177Pro Single submitter
p.Ser2302Ala Single submitter
p.Ser2364Arg Single submitter
p.Ser2579Asn Single submitter
p.Ser2579Gly Single submitter
p.Ser2658Pro Single submitter
p.Ser2706Asn Single submitter
p.Ser836Phe Single submitter
p.Ser869Asn Single submitter
p.Ser895Phe Single submitter
p.Thr1055Met Single submitter
p.Thr1096Ser Single submitter
p.Thr1768Ala Single submitter
p.Thr1775Ser Single submitter
p.Thr1877Met Single submitter
p.Thr1901Ala Single submitter
p.Thr2205Ala Single submitter
p.Thr2208Arg Single submitter
p.Thr2281Ala Single submitter
p.Thr2333Ser Single submitter
p.Thr2334Ala Single submitter
p.Thr2402Ala Single submitter
p.Thr2646Ala Single submitter
p.Thr2683Ile Single submitter
p.Thr2723Ile Single submitter
p.Thr276Lys Single submitter
p.Thr846Ala Single submitter
p.Thr84Ala Single submitter
p.Thr889Ile Single submitter
p.Thr905Ile Single submitter
p.Trp289Cys Single submitter
p.Tyr2181Cys Single submitter
p.Tyr2393Cys Single submitter
p.Tyr26Phe Single submitter
p.Tyr392Cys Single submitter
p.Val1049Phe Single submitter
p.Val1134Ile Single submitter