PTPRS — 415 ClinVar variants
All ClinVar germline PTPRS variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 299 flagged for review →
1 Likely pathogenic · 25 Benign · 1 Benign/Likely benign · 75 Likely benign · 313 Uncertain significance
Full PTPRS gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 299
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 216
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 216
- PTPRS p.Arg1572Trp Uncertain significance Multiple submitters
- PTPRS p.Ala109Val Uncertain significance Single submitter
- PTPRS p.Ala1118Thr Uncertain significance Single submitter
- PTPRS p.Ala1129Thr Uncertain significance Single submitter
- PTPRS p.Ala1129Val Uncertain significance Single submitter
- PTPRS p.Ala1331Thr Uncertain significance Single submitter
- PTPRS p.Ala1379Val Uncertain significance Single submitter
- PTPRS p.Ala1427Val Uncertain significance Single submitter
- PTPRS p.Ala1460Val Uncertain significance Single submitter
- PTPRS p.Ala1485Thr Uncertain significance Single submitter
- PTPRS p.Ala1604Ser Uncertain significance Single submitter
- PTPRS p.Ala1700Thr Uncertain significance Single submitter
- PTPRS p.Ala440Val Uncertain significance Single submitter
- PTPRS p.Ala604Thr Uncertain significance Single submitter
- PTPRS p.Ala729Glu Uncertain significance Single submitter
- PTPRS p.Ala734Asp Uncertain significance Single submitter
- PTPRS p.Ala736Ser Uncertain significance Single submitter
- PTPRS p.Ala766Thr Uncertain significance Single submitter
- PTPRS p.Ala804Thr Uncertain significance Single submitter
- PTPRS p.Ala819Thr Uncertain significance Single submitter
- PTPRS p.Ala850Ser Uncertain significance Single submitter
- PTPRS p.Ala899Ser Uncertain significance Single submitter
- PTPRS p.Ala937Val Uncertain significance Single submitter
- PTPRS p.Ala941Thr Uncertain significance Single submitter
- PTPRS p.Ala941Val Uncertain significance Single submitter
- PTPRS p.Ala986Val Uncertain significance Single submitter
- PTPRS p.Ala991Thr Uncertain significance Single submitter
- PTPRS p.Arg1015His Uncertain significance Single submitter
- PTPRS p.Arg1016Gln Uncertain significance Single submitter
- PTPRS p.Arg1016Trp Uncertain significance Single submitter
- PTPRS p.Arg1032Gly Uncertain significance Single submitter
- PTPRS p.Arg1165His Uncertain significance Single submitter
- PTPRS p.Arg1190Gln Uncertain significance Single submitter
- PTPRS p.Arg1200Cys Uncertain significance Single submitter
- PTPRS p.Arg1212His Uncertain significance Single submitter
- PTPRS p.Arg1241His Uncertain significance Single submitter
- PTPRS p.Arg1354Gly Uncertain significance Single submitter
- PTPRS p.Arg1421His Uncertain significance Single submitter
- PTPRS p.Arg1456Gly Uncertain significance Single submitter
- PTPRS p.Arg1456Trp Uncertain significance Single submitter
- PTPRS p.Arg1498Gln Uncertain significance Single submitter
- PTPRS p.Arg1595His Uncertain significance Single submitter
- PTPRS p.Arg1608Trp Uncertain significance Single submitter
- PTPRS p.Arg1628Cys Uncertain significance Single submitter
- PTPRS p.Arg1710Cys Uncertain significance Single submitter
- PTPRS p.Arg1710His Uncertain significance Single submitter
- PTPRS p.Arg1710Leu Uncertain significance Single submitter
- PTPRS p.Arg1783Trp Uncertain significance Single submitter
- PTPRS p.Arg1899Gln Uncertain significance Single submitter
- PTPRS p.Arg1916Gln Uncertain significance Single submitter
- PTPRS p.Arg295Gln Uncertain significance Single submitter
- PTPRS p.Arg420His Uncertain significance Single submitter
- PTPRS p.Arg532Gln Uncertain significance Single submitter
- PTPRS p.Arg561Gln Uncertain significance Single submitter
- PTPRS p.Arg567Gln Uncertain significance Single submitter
- PTPRS p.Arg597His Uncertain significance Single submitter
- PTPRS p.Arg610Gln Uncertain significance Single submitter
- PTPRS p.Arg725Gln Uncertain significance Single submitter
-
PTPRS p.Arg851Leu
Uncertain significance
Single submitter
hearing loss disorder
- PTPRS p.Arg889Cys Uncertain significance Single submitter
- PTPRS p.Arg889Gly Uncertain significance Single submitter
- PTPRS p.Arg908Trp Uncertain significance Single submitter
- PTPRS p.Arg910His Uncertain significance Single submitter
- PTPRS p.Arg910Leu Uncertain significance Single submitter
- PTPRS p.Arg929His Uncertain significance Single submitter
- PTPRS p.Arg929Pro Uncertain significance Single submitter
- PTPRS p.Arg970Gln Uncertain significance Single submitter
- PTPRS p.Asn1061Asp Uncertain significance Single submitter
- PTPRS p.Asn1096Asp Uncertain significance Single submitter
- PTPRS p.Asn136Ser Uncertain significance Single submitter
- PTPRS p.Asn474Thr Uncertain significance Single submitter
- PTPRS p.Asn798Asp Uncertain significance Single submitter
- PTPRS p.Asp1003Asn Uncertain significance Single submitter
- PTPRS p.Asp1224Asn Uncertain significance Single submitter
- PTPRS p.Asp1232Asn Uncertain significance Single submitter
- PTPRS p.Asp1269Asn Uncertain significance Single submitter
- PTPRS p.Asp1311Asn Uncertain significance Single submitter
- PTPRS p.Asp1329Asn Uncertain significance Single submitter
- PTPRS p.Asp1377Asn Uncertain significance Single submitter
- PTPRS p.Asp1927His Uncertain significance Single submitter
- PTPRS p.Asp482Asn Uncertain significance Single submitter
- PTPRS p.Asp564Asn Uncertain significance Single submitter
- PTPRS p.Asp716Asn Uncertain significance Single submitter
- PTPRS p.Asp718Gly Uncertain significance Single submitter
- PTPRS p.Cys1790Ser Uncertain significance Single submitter
- PTPRS p.Cys1790Tyr Uncertain significance Single submitter
- PTPRS p.Gln1192Arg Uncertain significance Single submitter
- PTPRS p.Gln280His Uncertain significance Single submitter
- PTPRS p.Gln783Glu Uncertain significance Single submitter
- PTPRS p.Glu1254Lys Uncertain significance Single submitter
- PTPRS p.Glu1525Lys Uncertain significance Single submitter
- PTPRS p.Glu1635Lys Uncertain significance Single submitter
- PTPRS p.Glu495Lys Uncertain significance Single submitter
- PTPRS p.Glu534Lys Uncertain significance Single submitter
- PTPRS p.Glu582Lys Uncertain significance Single submitter
- PTPRS p.Glu684Lys Uncertain significance Single submitter
- PTPRS p.Glu767Lys Uncertain significance Single submitter
- PTPRS p.Glu802Asp Uncertain significance Single submitter
- PTPRS p.Glu916Ala Uncertain significance Single submitter
- PTPRS p.Gly1103Ser Uncertain significance Single submitter
- PTPRS p.Gly1136Asp Uncertain significance Single submitter
- PTPRS p.Gly1230Ser Uncertain significance Single submitter
- PTPRS p.Gly1352Asp Uncertain significance Single submitter
- PTPRS p.Gly1592Ser Uncertain significance Single submitter
- PTPRS p.Gly1848Ser Uncertain significance Single submitter
- PTPRS p.Gly1883Ser Uncertain significance Single submitter
- PTPRS p.Gly336Arg Uncertain significance Single submitter
- PTPRS p.Gly391Ser Uncertain significance Single submitter
- PTPRS p.Gly649Arg Uncertain significance Single submitter
- PTPRS p.Gly846Asp Uncertain significance Single submitter
- PTPRS p.Gly898Arg Uncertain significance Single submitter
- PTPRS p.Gly911Ser Uncertain significance Single submitter
- PTPRS p.Gly944Arg Uncertain significance Single submitter
- PTPRS p.His1430Arg Uncertain significance Single submitter
- PTPRS p.His750Pro Uncertain significance Single submitter
- PTPRS p.His759Tyr Uncertain significance Single submitter
- PTPRS p.Ile1156Val Uncertain significance Single submitter
- PTPRS p.Ile1462Val Uncertain significance Single submitter
- PTPRS p.Ile1516Val Uncertain significance Single submitter
- PTPRS p.Ile348Phe Uncertain significance Single submitter
- PTPRS p.Ile348Val Uncertain significance Single submitter
- PTPRS p.Ile389Val Uncertain significance Single submitter
- PTPRS p.Ile43Val Uncertain significance Single submitter
- PTPRS p.Leu1051Val Uncertain significance Single submitter
- PTPRS p.Leu1181Met Uncertain significance Single submitter
- PTPRS p.Leu19Phe Uncertain significance Single submitter
- PTPRS p.Leu868Gln Uncertain significance Single submitter
- PTPRS p.Leu881Val Uncertain significance Single submitter
-
PTPRS p.Leu995Phe
Uncertain significance
Single submitter
PTPRS-related disorder
- PTPRS p.Lys185Arg Uncertain significance Single submitter
- PTPRS p.Met1139Thr Uncertain significance Single submitter
- PTPRS p.Met1442Thr Uncertain significance Single submitter
- PTPRS p.Met1478Val Uncertain significance Single submitter
- PTPRS p.Met443Val Uncertain significance Single submitter
- PTPRS p.Met529Thr Uncertain significance Single submitter
- PTPRS p.Met763Leu Uncertain significance Single submitter
- PTPRS p.Phe1364Ser Uncertain significance Single submitter
- PTPRS p.Phe1740Ser Uncertain significance Single submitter
- PTPRS p.Pro1023Ser Uncertain significance Single submitter
- PTPRS p.Pro1023Thr Uncertain significance Single submitter
- PTPRS p.Pro1024Ala Uncertain significance Single submitter
- PTPRS p.Pro1024Ser Uncertain significance Single submitter
- PTPRS p.Pro1057Ser Uncertain significance Single submitter
- PTPRS p.Pro1063Thr Uncertain significance Single submitter
- PTPRS p.Pro1065Ala Uncertain significance Single submitter
- PTPRS p.Pro1130Ser Uncertain significance Single submitter
- PTPRS p.Pro1222Ala Uncertain significance Single submitter
- PTPRS p.Pro1271Leu Uncertain significance Single submitter
- PTPRS p.Pro1332Leu Uncertain significance Single submitter
- PTPRS p.Pro1360Leu Uncertain significance Single submitter
Predictors split 83
The independent predictors disagree with each other — read with care.
- PTPRS p.Ala1485Val Uncertain significance Single submitter
- PTPRS p.Ala157Thr Uncertain significance Single submitter
- PTPRS p.Ala1752Thr Uncertain significance Single submitter
- PTPRS p.Ala595Thr Uncertain significance Single submitter
- PTPRS p.Arg1015Cys Uncertain significance Single submitter
- PTPRS p.Arg1026His Uncertain significance Single submitter
- PTPRS p.Arg1190Trp Uncertain significance Single submitter
- PTPRS p.Arg1194His Uncertain significance Single submitter
- PTPRS p.Arg1206Pro Uncertain significance Single submitter
- PTPRS p.Arg1314Cys Uncertain significance Single submitter
- PTPRS p.Arg1343His Uncertain significance Single submitter
- PTPRS p.Arg1659Cys Uncertain significance Single submitter
- PTPRS p.Arg1686Trp Uncertain significance Single submitter
- PTPRS p.Arg561Trp Uncertain significance Single submitter
- PTPRS p.Arg567Trp Uncertain significance Single submitter
- PTPRS p.Arg593Cys Uncertain significance Single submitter
- PTPRS p.Arg597Cys Uncertain significance Single submitter
- PTPRS p.Arg612Gly Uncertain significance Single submitter
- PTPRS p.Arg762Cys Uncertain significance Single submitter
- PTPRS p.Arg762His Uncertain significance Single submitter
- PTPRS p.Arg769Cys Uncertain significance Single submitter
- PTPRS p.Arg835Cys Uncertain significance Single submitter
- PTPRS p.Arg835His Uncertain significance Single submitter
- PTPRS p.Arg851Cys Uncertain significance Single submitter
- PTPRS p.Arg904Gln Uncertain significance Single submitter
- PTPRS p.Arg949Cys Uncertain significance Single submitter
- PTPRS p.Arg970Trp Uncertain significance Single submitter
- PTPRS p.Asn1412Lys Uncertain significance Single submitter
- PTPRS p.Asp1178Val Uncertain significance Single submitter
- PTPRS p.Asp138Asn Uncertain significance Single submitter
- PTPRS p.Asp1636Asn Uncertain significance Single submitter
- PTPRS p.Asp1858Glu Uncertain significance Single submitter
- PTPRS p.Asp289Asn Uncertain significance Single submitter
- PTPRS p.Asp353Glu Uncertain significance Single submitter
- PTPRS p.Asp574His Uncertain significance Single submitter
- PTPRS p.Asp716His Uncertain significance Single submitter
- PTPRS p.Cys1323Tyr Uncertain significance Single submitter
- PTPRS p.Cys1723Phe Uncertain significance Single submitter
- PTPRS p.Glu106Asp Uncertain significance Single submitter
- PTPRS p.Glu1340Gln Uncertain significance Single submitter
- PTPRS p.Glu1643Lys Uncertain significance Single submitter
- PTPRS p.Glu887Lys Uncertain significance Single submitter
- PTPRS p.Gly1136Ser Uncertain significance Single submitter
- PTPRS p.Gly1674Asp Uncertain significance Single submitter
- PTPRS p.Ile1297Ser Uncertain significance Single submitter
- PTPRS p.Ile184Met Uncertain significance Single submitter
- PTPRS p.Leu913Arg Uncertain significance Single submitter
- PTPRS p.Lys1041Met Uncertain significance Single submitter
- PTPRS p.Lys1322Gln Uncertain significance Single submitter
- PTPRS p.Met1767Val Uncertain significance Single submitter
- PTPRS p.Met1914Thr Uncertain significance Single submitter
- PTPRS p.Met1922Val Uncertain significance Single submitter
- PTPRS p.Met314Val Uncertain significance Single submitter
- PTPRS p.Met778Ile Uncertain significance Single submitter
- PTPRS p.Phe1169Leu Uncertain significance Single submitter
- PTPRS p.Phe1707Leu Uncertain significance Single submitter
- PTPRS p.Phe1707Ser Uncertain significance Single submitter
- PTPRS p.Pro1024Arg Uncertain significance Single submitter
- PTPRS p.Pro1024Thr Uncertain significance Single submitter
- PTPRS p.Pro1402Thr Uncertain significance Single submitter
- PTPRS p.Pro1579Ser Uncertain significance Single submitter
- PTPRS p.Pro641Leu Uncertain significance Single submitter
- PTPRS p.Pro885Leu Uncertain significance Single submitter
- PTPRS p.Pro924Leu Uncertain significance Single submitter
- PTPRS p.Ser1022Gly Uncertain significance Single submitter
- PTPRS p.Ser1484Leu Uncertain significance Single submitter
- PTPRS p.Ser1699Asn Uncertain significance Single submitter
- PTPRS p.Ser1852Leu Likely benign Single submitter
- PTPRS p.Ser942Leu Uncertain significance Single submitter
- PTPRS p.Thr1004Met Uncertain significance Single submitter
- PTPRS p.Thr1082Ile Uncertain significance Single submitter
- PTPRS p.Thr1510Met Uncertain significance Single submitter
- PTPRS p.Thr1519Met Uncertain significance Single submitter
- PTPRS p.Thr209Ile Uncertain significance Single submitter
- PTPRS p.Thr572Pro Uncertain significance Single submitter
- PTPRS p.Thr677Ile Uncertain significance Single submitter
- PTPRS p.Tyr1662Cys Uncertain significance Single submitter
- PTPRS p.Tyr792His Uncertain significance Single submitter
- PTPRS p.Val1294Ala Uncertain significance Single submitter
- PTPRS p.Val1615Ala Uncertain significance Single submitter
- PTPRS p.Val499Met Uncertain significance Single submitter
-
PTPRS p.Arg872Cys
Likely benign
No assertion criteria
PTPRS-related disorder
-
PTPRS p.His1693Gln
Uncertain significance
No assertion criteria
PTPRS-related disorder
All PTPRS variants
Likely pathogenic 1
- p.Val1586Met No assertion criteria NK-cell enteropathy
Benign 25
- p.Ala87= Multiple submitters
- p.Ala972= Multiple submitters
- p.Asn1737= Multiple submitters
- p.His1642= Multiple submitters
- p.Ile1741= Multiple submitters
- p.Leu1170= Multiple submitters
- p.Pro95= Multiple submitters
- p.Ser11= Multiple submitters
- p.Ser1253= Multiple submitters
- p.Thr1114= Multiple submitters
- p.Thr327= Multiple submitters
- p.Thr858= Multiple submitters
- c.2377-10G>A Single submitter
- c.4770-6C>T Single submitter
- p.Val697= Single submitter
- c.2495-8C>T No assertion criteria PTPRS-related disorder
- p.Ala1648= No assertion criteria PTPRS-related disorder
- p.Ala268= No assertion criteria PTPRS-related disorder
- p.Cys27Tyr No assertion criteria PTPRS-related disorder
- p.Ile1857= No assertion criteria PTPRS-related disorder
- p.Lys1500= No assertion criteria PTPRS-related disorder
- p.Pro1255Ala No assertion criteria PTPRS-related disorder
- p.Ser1444= No assertion criteria PTPRS-related disorder
- p.Thr80= No assertion criteria PTPRS-related disorder
- p.Val113Ala No assertion criteria PTPRS-related disorder
Benign/Likely benign 1
- p.Thr191= Multiple submitters
Likely benign 75
- p.Glu165= Multiple submitters
- p.Gly1107= Multiple submitters
- c.3202-4G>A Single submitter
- c.4318+7C>T Single submitter
- p.Ala1328= Single submitter
- p.Ala1554= Single submitter
- p.Ala1591= Single submitter
- p.Ala780= Single submitter
- p.Ala943= Single submitter
- p.Arg1032Gln Single submitter
- p.Asp716= Single submitter
- p.Gly1124Ser Single submitter
- p.Gly653Ser Single submitter
- p.Leu502= Single submitter
- p.Pro1310= Single submitter
- p.Ser1199= Single submitter
- p.Ser1852Leu Single submitter ⚠
- p.Thr1029= Single submitter
- p.Thr1382= Single submitter
- p.Thr1622= Single submitter
- p.Thr1694= Single submitter
- p.Thr310= Single submitter
- p.Thr808= Single submitter
- p.Thr996= Single submitter
- p.Val462Ile Single submitter
- c.2156-24CTCCC[2] No assertion criteria PTPRS-related disorder
- c.2495-4G>A No assertion criteria PTPRS-related disorder
- c.3103+7G>A No assertion criteria PTPRS-related disorder
- c.3103+8C>T No assertion criteria PTPRS-related disorder
- c.4194+9A>C No assertion criteria PTPRS-related disorder
- c.4614+10_4614+15del No assertion criteria PTPRS-related disorder
- c.5778+7A>C No assertion criteria PTPRS-related disorder
- c.5779-10G>T No assertion criteria PTPRS-related disorder
- p.Ala1248= No assertion criteria PTPRS-related disorder
- p.Ala1379= No assertion criteria PTPRS-related disorder
- p.Ala1752= No assertion criteria PTPRS-related disorder
- p.Ala1758= No assertion criteria PTPRS-related disorder
- p.Ala620= No assertion criteria PTPRS-related disorder
- p.Ala978= No assertion criteria PTPRS-related disorder
- p.Ala986= No assertion criteria PTPRS-related disorder
- p.Arg872Cys No assertion criteria PTPRS-related disorder ⚠
- p.Asn940= No assertion criteria PTPRS-related disorder
- p.Asp1135= No assertion criteria PTPRS-related disorder
- p.Asp1144= No assertion criteria PTPRS-related disorder
- p.Asp290= No assertion criteria PTPRS-related disorder
- p.Gln1405= No assertion criteria PTPRS-related disorder
- p.Gln1924= No assertion criteria PTPRS-related disorder
- p.Glu589= No assertion criteria PTPRS-related disorder
- p.Gly1229= No assertion criteria PTPRS-related disorder
- p.Gly411= No assertion criteria PTPRS-related disorder
- p.His1088= No assertion criteria PTPRS-related disorder
- p.Ile1602= No assertion criteria PTPRS-related disorder
- p.Leu1305= No assertion criteria PTPRS-related disorder
- p.Leu983= No assertion criteria PTPRS-related disorder
- p.Pro1024= No assertion criteria PTPRS-related disorder
- p.Pro1556= No assertion criteria PTPRS-related disorder
- p.Pro1845= No assertion criteria PTPRS-related disorder
- p.Pro468= No assertion criteria PTPRS-related disorder
- p.Pro599= No assertion criteria PTPRS-related disorder
- p.Pro644= No assertion criteria PTPRS-related disorder
- p.Pro953= No assertion criteria PTPRS-related disorder
- p.Ser1127= No assertion criteria PTPRS-related disorder
- p.Ser1399= No assertion criteria PTPRS-related disorder
- p.Ser1484= No assertion criteria PTPRS-related disorder
- p.Ser537= No assertion criteria PTPRS-related disorder
- p.Ser839= No assertion criteria PTPRS-related disorder
- p.Ser886= No assertion criteria PTPRS-related disorder
- p.Thr1464= No assertion criteria PTPRS-related disorder
- p.Thr1519= No assertion criteria PTPRS-related disorder
- p.Thr1565= No assertion criteria PTPRS-related disorder
- p.Thr1634= No assertion criteria PTPRS-related disorder
- p.Thr1917= No assertion criteria PTPRS-related disorder
- p.Thr498= No assertion criteria PTPRS-related disorder
- p.Tyr1750= No assertion criteria PTPRS-related disorder
- p.Tyr460= No assertion criteria PTPRS-related disorder
Uncertain significance 313
Showing the top 300 by review status; the full set is in the sitemap.
- p.Arg1572Trp Multiple submitters ⚠
- c.4048+14C>T Single submitter
- p.Ala109Val Single submitter ⚠
- p.Ala1118Thr Single submitter ⚠
- p.Ala1129Thr Single submitter ⚠
- p.Ala1129Val Single submitter ⚠
- p.Ala1331Thr Single submitter ⚠
- p.Ala1379Val Single submitter ⚠
- p.Ala1427Val Single submitter ⚠
- p.Ala1460Val Single submitter ⚠
- p.Ala1485Thr Single submitter ⚠
- p.Ala1485Val Single submitter ⚠
- p.Ala157Thr Single submitter ⚠
- p.Ala1604Ser Single submitter ⚠
- p.Ala1700Thr Single submitter ⚠
- p.Ala1752Thr Single submitter ⚠
- p.Ala440Val Single submitter ⚠
- p.Ala595Thr Single submitter ⚠
- p.Ala604Thr Single submitter ⚠
- p.Ala729Glu Single submitter ⚠
- p.Ala734Asp Single submitter ⚠
- p.Ala736Ser Single submitter ⚠
- p.Ala766Thr Single submitter ⚠
- p.Ala804Thr Single submitter ⚠
- p.Ala819Thr Single submitter ⚠
- p.Ala850Ser Single submitter ⚠
- p.Ala899Ser Single submitter ⚠
- p.Ala937Val Single submitter ⚠
- p.Ala941Thr Single submitter ⚠
- p.Ala941Val Single submitter ⚠
- p.Ala986Val Single submitter ⚠
- p.Ala991Thr Single submitter ⚠
- p.Arg1015Cys Single submitter ⚠
- p.Arg1015His Single submitter ⚠
- p.Arg1016Gln Single submitter ⚠
- p.Arg1016Trp Single submitter ⚠
- p.Arg1026His Single submitter ⚠
- p.Arg1032Gly Single submitter ⚠
- p.Arg1165His Single submitter ⚠
- p.Arg1190Gln Single submitter ⚠
- p.Arg1190Trp Single submitter ⚠
- p.Arg1194His Single submitter ⚠
- p.Arg1200Cys Single submitter ⚠
- p.Arg1206Pro Single submitter ⚠
- p.Arg1212His Single submitter ⚠
- p.Arg1241His Single submitter ⚠
- p.Arg1314Cys Single submitter ⚠
- p.Arg1343His Single submitter ⚠
- p.Arg1354Gly Single submitter ⚠
- p.Arg1421His Single submitter ⚠
- p.Arg1456Gly Single submitter ⚠
- p.Arg1456Trp Single submitter ⚠
- p.Arg1498Gln Single submitter ⚠
- p.Arg1595His Single submitter ⚠
- p.Arg1608Trp Single submitter ⚠
- p.Arg1628Cys Single submitter ⚠
- p.Arg1659Cys Single submitter ⚠
- p.Arg1686Trp Single submitter ⚠
- p.Arg1710Cys Single submitter ⚠
- p.Arg1710His Single submitter ⚠
- p.Arg1710Leu Single submitter ⚠
- p.Arg1783Trp Single submitter ⚠
- p.Arg1886Lys Single submitter
- p.Arg1899Gln Single submitter ⚠
- p.Arg1916Gln Single submitter ⚠
- p.Arg246His Single submitter
- p.Arg295Gln Single submitter ⚠
- p.Arg420His Single submitter ⚠
- p.Arg532Gln Single submitter ⚠
- p.Arg549Trp Single submitter
- p.Arg561Gln Single submitter ⚠
- p.Arg561Trp Single submitter ⚠
- p.Arg567Gln Single submitter ⚠
- p.Arg567Trp Single submitter ⚠
- p.Arg593Cys Single submitter ⚠
- p.Arg597Cys Single submitter ⚠
- p.Arg597His Single submitter ⚠
- p.Arg610Gln Single submitter ⚠
- p.Arg612Gly Single submitter ⚠
- p.Arg725Gln Single submitter ⚠
- p.Arg762Cys Single submitter ⚠
- p.Arg762His Single submitter ⚠
- p.Arg769Cys Single submitter ⚠
- p.Arg835Cys Single submitter ⚠
- p.Arg835His Single submitter ⚠
- p.Arg851Cys Single submitter ⚠
- p.Arg851Leu Single submitter hearing loss disorder ⚠
- p.Arg867Cys Single submitter
- p.Arg872His Single submitter
- p.Arg889Cys Single submitter ⚠
- p.Arg889Gly Single submitter ⚠
- p.Arg904Gln Single submitter ⚠
- p.Arg908Trp Single submitter ⚠
- p.Arg910His Single submitter ⚠
- p.Arg910Leu Single submitter ⚠
- p.Arg929His Single submitter ⚠
- p.Arg929Pro Single submitter ⚠
- p.Arg949Cys Single submitter ⚠
- p.Arg970Gln Single submitter ⚠
- p.Arg970Trp Single submitter ⚠
- p.Asn1061Asp Single submitter ⚠
- p.Asn1096Asp Single submitter ⚠
- p.Asn136Ser Single submitter ⚠
- p.Asn1412Lys Single submitter ⚠
- p.Asn474Thr Single submitter ⚠
- p.Asn798Asp Single submitter ⚠
- p.Asp1003Asn Single submitter ⚠
- p.Asp1178Val Single submitter ⚠
- p.Asp1224Asn Single submitter ⚠
- p.Asp1232Asn Single submitter ⚠
- p.Asp1269Asn Single submitter ⚠
- p.Asp1311Asn Single submitter ⚠
- p.Asp1329Asn Single submitter ⚠
- p.Asp1377Asn Single submitter ⚠
- p.Asp138Asn Single submitter ⚠
- p.Asp1636Asn Single submitter ⚠
- p.Asp1858Glu Single submitter ⚠
- p.Asp1927His Single submitter ⚠
- p.Asp289Asn Single submitter ⚠
- p.Asp353Glu Single submitter ⚠
- p.Asp482Asn Single submitter ⚠
- p.Asp564Asn Single submitter ⚠
- p.Asp574His Single submitter ⚠
- p.Asp716Asn Single submitter ⚠
- p.Asp716His Single submitter ⚠
- p.Asp718Gly Single submitter ⚠
- p.Cys1323Tyr Single submitter ⚠
- p.Cys1723Phe Single submitter ⚠
- p.Cys1790Ser Single submitter ⚠
- p.Cys1790Tyr Single submitter ⚠
- p.Gln1192Arg Single submitter ⚠
- p.Gln1503Glu Single submitter
- p.Gln280His Single submitter ⚠
- p.Gln783Glu Single submitter ⚠
- p.Glu106Asp Single submitter ⚠
- p.Glu1254Lys Single submitter ⚠
- p.Glu1340Gln Single submitter ⚠
- p.Glu1525Lys Single submitter ⚠
- p.Glu1635Lys Single submitter ⚠
- p.Glu1643Lys Single submitter ⚠
- p.Glu495Lys Single submitter ⚠
- p.Glu534Lys Single submitter ⚠
- p.Glu582Lys Single submitter ⚠
- p.Glu684Lys Single submitter ⚠
- p.Glu730Gly Single submitter
- p.Glu767Lys Single submitter ⚠
- p.Glu802Asp Single submitter ⚠
- p.Glu887Lys Single submitter ⚠
- p.Glu916Ala Single submitter ⚠
- p.Gly1103Ser Single submitter ⚠
- p.Gly1136Asp Single submitter ⚠
- p.Gly1136Ser Single submitter ⚠
- p.Gly1230Ser Single submitter ⚠
- p.Gly1239Ser Single submitter
- p.Gly1352Asp Single submitter ⚠
- p.Gly1592Ser Single submitter ⚠
- p.Gly1674Asp Single submitter ⚠
- p.Gly1848Ser Single submitter ⚠
- p.Gly1883Ser Single submitter ⚠
- p.Gly336Arg Single submitter ⚠
- p.Gly391Ser Single submitter ⚠
- p.Gly649Arg Single submitter ⚠
- p.Gly846Asp Single submitter ⚠
- p.Gly898Arg Single submitter ⚠
- p.Gly911Ser Single submitter ⚠
- p.Gly944Arg Single submitter ⚠
- p.His1430Arg Single submitter ⚠
- p.His750Pro Single submitter ⚠
- p.His759Tyr Single submitter ⚠
- p.Ile1156Val Single submitter ⚠
- p.Ile1297Ser Single submitter ⚠
- p.Ile1462Val Single submitter ⚠
- p.Ile1516Val Single submitter ⚠
- p.Ile184Met Single submitter ⚠
- p.Ile348Phe Single submitter ⚠
- p.Ile348Val Single submitter ⚠
- p.Ile389Val Single submitter ⚠
- p.Ile43Val Single submitter ⚠
- p.Leu1051Val Single submitter ⚠
- p.Leu1181Met Single submitter ⚠
- p.Leu19Phe Single submitter ⚠
- p.Leu732Phe Single submitter
- p.Leu868Gln Single submitter ⚠
- p.Leu881Val Single submitter ⚠
- p.Leu913Arg Single submitter ⚠
- p.Leu995Phe Single submitter PTPRS-related disorder ⚠
- p.Lys1041Met Single submitter ⚠
- p.Lys1322Gln Single submitter ⚠
- p.Lys185Arg Single submitter ⚠
- p.Met1139Thr Single submitter ⚠
- p.Met1442Thr Single submitter ⚠
- p.Met1478Val Single submitter ⚠
- p.Met1767Val Single submitter ⚠
- p.Met1914Thr Single submitter ⚠
- p.Met1922Val Single submitter ⚠
- p.Met314Val Single submitter ⚠
- p.Met443Val Single submitter ⚠
- p.Met529Thr Single submitter ⚠
- p.Met763Leu Single submitter ⚠
- p.Met778Ile Single submitter ⚠
- p.Phe1169Leu Single submitter ⚠
- p.Phe1364Ser Single submitter ⚠
- p.Phe1707Leu Single submitter ⚠
- p.Phe1707Ser Single submitter ⚠
- p.Phe1740Ser Single submitter ⚠
- p.Pro1023Ser Single submitter ⚠
- p.Pro1023Thr Single submitter ⚠
- p.Pro1024Ala Single submitter ⚠
- p.Pro1024Arg Single submitter ⚠
- p.Pro1024Ser Single submitter ⚠
- p.Pro1024Thr Single submitter ⚠
- p.Pro1057Ser Single submitter ⚠
- p.Pro1063Thr Single submitter ⚠
- p.Pro1065Ala Single submitter ⚠
- p.Pro1130Ser Single submitter ⚠
- p.Pro1222Ala Single submitter ⚠
- p.Pro1271Leu Single submitter ⚠
- p.Pro1332Leu Single submitter ⚠
- p.Pro1360Leu Single submitter ⚠
- p.Pro1402Thr Single submitter ⚠
- p.Pro1579Leu Single submitter ⚠
- p.Pro1579Ser Single submitter ⚠
- p.Pro1657Ser Single submitter ⚠
- p.Pro1756Ser Single submitter ⚠
- p.Pro1816Leu Single submitter ⚠
- p.Pro359Thr Single submitter ⚠
- p.Pro525Leu Single submitter ⚠
- p.Pro575Leu Single submitter
- p.Pro641Leu Single submitter ⚠
- p.Pro644Ala Single submitter ⚠
- p.Pro668Ala Single submitter ⚠
- p.Pro723Leu Single submitter ⚠
- p.Pro771Ser Single submitter ⚠
- p.Pro7Leu Single submitter ⚠
- p.Pro885Leu Single submitter ⚠
- p.Pro924Leu Single submitter ⚠
- p.Pro955Leu Single submitter ⚠
- p.Pro984Leu Single submitter ⚠
- p.Pro984Ser Single submitter ⚠
- p.Pro989Leu Single submitter ⚠
- p.Ser1022Gly Single submitter ⚠
- p.Ser1036Leu Single submitter ⚠
- p.Ser1484Leu Single submitter ⚠
- p.Ser1626Phe Single submitter ⚠
- p.Ser1699Asn Single submitter ⚠
- p.Ser1739Thr Single submitter
- p.Ser205Asn Single submitter ⚠
- p.Ser552Asn Single submitter ⚠
- p.Ser598Leu Single submitter ⚠
- p.Ser663Pro Single submitter ⚠
- p.Ser709Leu Single submitter ⚠
- p.Ser839Leu Single submitter ⚠
- p.Ser942Leu Single submitter ⚠
- p.Thr1004Met Single submitter ⚠
- p.Thr1082Ile Single submitter ⚠
- p.Thr1219Lys Single submitter ⚠
- p.Thr1321Ala Single submitter ⚠
- p.Thr1510Met Single submitter ⚠
- p.Thr1519Met Single submitter ⚠
- p.Thr151Ile Single submitter ⚠
- p.Thr1596Ala Single submitter ⚠
- p.Thr1634Met Single submitter ⚠
- p.Thr1654Pro Single submitter
- p.Thr1760Ala Single submitter ⚠
- p.Thr1892Lys Single submitter PTPRS-related disorder ⚠
- p.Thr1948Ala Single submitter
- p.Thr195Ala Single submitter ⚠
- p.Thr209Ile Single submitter ⚠
- p.Thr539Ile Single submitter ⚠
- p.Thr539Ser Single submitter ⚠
- p.Thr542Met Single submitter ⚠
- p.Thr572Pro Single submitter ⚠
- p.Thr588Lys Single submitter
- p.Thr646Met Single submitter ⚠
- p.Thr677Ile Single submitter ⚠
- p.Thr876Met Single submitter ⚠
- p.Thr981Ser Single submitter ⚠
- p.Tyr1060Ser Single submitter ⚠
- p.Tyr1662Cys Single submitter ⚠
- p.Tyr1717Cys Single submitter ⚠
- p.Tyr792His Single submitter ⚠
- p.Val1025Ile Single submitter ⚠
- p.Val104Met Single submitter ⚠
- p.Val1128Ile Single submitter ⚠
- p.Val1204Gly Single submitter ⚠
- p.Val1277Leu Single submitter ⚠
- p.Val1277Met Single submitter ⚠
- p.Val1294Ala Single submitter ⚠
- p.Val12Leu Single submitter ⚠
- p.Val13Ile Single submitter PTPRS-related disorder ⚠
- p.Val1488Ile Single submitter ⚠
- p.Val1531Ile Single submitter ⚠
- p.Val1560Met Single submitter ⚠
- p.Val1615Ala Single submitter ⚠
- p.Val1677Ile Single submitter ⚠
- p.Val1884Met Single submitter ⚠
- p.Val297Met Single submitter ⚠
- p.Val364Ile Single submitter ⚠
- p.Val499Met Single submitter ⚠
- p.Val507Ile Single submitter ⚠