RABGGTA — 92 ClinVar variants
All ClinVar germline RABGGTA variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 88 flagged for review →
1 Benign · 91 Uncertain significance
Full RABGGTA gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 88
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 69
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- RABGGTA p.Val158Met Uncertain significance Multiple submitters
- RABGGTA p.Ala165Val Uncertain significance Single submitter
- RABGGTA p.Ala87Ser Uncertain significance Single submitter
- RABGGTA p.Arg101Gln Uncertain significance Single submitter
- RABGGTA p.Arg127Pro Uncertain significance Single submitter
- RABGGTA p.Arg134Leu Uncertain significance Single submitter
- RABGGTA p.Arg149Gln Uncertain significance Single submitter
- RABGGTA p.Arg173Gln Uncertain significance Single submitter
- RABGGTA p.Arg184Cys Uncertain significance Single submitter
- RABGGTA p.Arg202Cys Uncertain significance Single submitter
- RABGGTA p.Arg238Gln Uncertain significance Single submitter
- RABGGTA p.Arg246His Uncertain significance Single submitter
- RABGGTA p.Arg252Gln Uncertain significance Single submitter
- RABGGTA p.Arg270Thr Uncertain significance Single submitter
- RABGGTA p.Arg293Thr Uncertain significance Single submitter
- RABGGTA p.Arg295Trp Uncertain significance Single submitter
- RABGGTA p.Arg337His Uncertain significance Single submitter
- RABGGTA p.Arg337Leu Uncertain significance Single submitter
- RABGGTA p.Arg343Gln Uncertain significance Single submitter
- RABGGTA p.Arg393Trp Uncertain significance Single submitter
- RABGGTA p.Arg418Gln Uncertain significance Single submitter
- RABGGTA p.Arg426His Uncertain significance Single submitter
- RABGGTA p.Arg486His Uncertain significance Single submitter
- RABGGTA p.Arg509Gln Uncertain significance Single submitter
- RABGGTA p.Asn124Asp Uncertain significance Single submitter
- RABGGTA p.Asn124Ser Uncertain significance Single submitter
- RABGGTA p.Asn310His Uncertain significance Single submitter
- RABGGTA p.Asn473Ser Uncertain significance Single submitter
- RABGGTA p.Asn67Thr Uncertain significance Single submitter
- RABGGTA p.Asp168Asn Uncertain significance Single submitter
- RABGGTA p.Asp45Val Uncertain significance Single submitter
- RABGGTA p.Gln190His Uncertain significance Single submitter
- RABGGTA p.Gln375Arg Uncertain significance Single submitter
- RABGGTA p.Gln522His Uncertain significance Single submitter
- RABGGTA p.Glu369Asp Uncertain significance Single submitter
- RABGGTA p.Glu43Asp Uncertain significance Single submitter
- RABGGTA p.Glu442Lys Uncertain significance Single submitter
- RABGGTA p.Glu77Gly Uncertain significance Single submitter
- RABGGTA p.Gly268Cys Uncertain significance Single submitter
- RABGGTA p.Gly503Ser Uncertain significance Single submitter
- RABGGTA p.His182Tyr Uncertain significance Single submitter
- RABGGTA p.His316Arg Uncertain significance Single submitter
- RABGGTA p.Ile321Ser Uncertain significance Single submitter
- RABGGTA p.Ile388Val Uncertain significance Single submitter
- RABGGTA p.Leu236Arg Uncertain significance Single submitter
- RABGGTA p.Leu405Val Uncertain significance Single submitter
- RABGGTA p.Leu430Phe Uncertain significance Single submitter
- RABGGTA p.Leu537Phe Uncertain significance Single submitter
- RABGGTA p.Leu537Val Uncertain significance Single submitter
- RABGGTA p.Met277Arg Uncertain significance Single submitter
- RABGGTA p.Pro282Leu Uncertain significance Single submitter
- RABGGTA p.Pro314Ser Uncertain significance Single submitter
- RABGGTA p.Pro523Ser Uncertain significance Single submitter
- RABGGTA p.Pro82Ala Uncertain significance Single submitter
- RABGGTA p.Thr289Asn Uncertain significance Single submitter
- RABGGTA p.Thr317Ile Uncertain significance Single submitter
- RABGGTA p.Thr346Met Uncertain significance Single submitter
- RABGGTA p.Thr420Met Uncertain significance Single submitter
- RABGGTA p.Thr477Ser Uncertain significance Single submitter
- RABGGTA p.Trp383Ser Uncertain significance Single submitter
- RABGGTA p.Tyr421Cys Uncertain significance Single submitter
- RABGGTA p.Val152Met Uncertain significance Single submitter
- RABGGTA p.Val332Met Uncertain significance Single submitter
- RABGGTA p.Val35Ile Uncertain significance Single submitter
- RABGGTA p.Val35Leu Uncertain significance Single submitter
- RABGGTA p.Val414Met Uncertain significance Single submitter
- RABGGTA p.Val435Met Uncertain significance Single submitter
- RABGGTA p.Val455Glu Uncertain significance Single submitter
- RABGGTA p.Val48Met Uncertain significance Single submitter
Predictors split 19
The independent predictors disagree with each other — read with care.
- RABGGTA p.Arg101Trp Uncertain significance Single submitter
- RABGGTA p.Arg119Cys Uncertain significance Single submitter
- RABGGTA p.Arg134Cys Uncertain significance Single submitter
- RABGGTA p.Arg263Trp Uncertain significance Single submitter
- RABGGTA p.Arg39His Uncertain significance Single submitter
- RABGGTA p.Arg509Trp Uncertain significance Single submitter
- RABGGTA p.Asp424Glu Uncertain significance Single submitter
- RABGGTA p.Glu339Lys Uncertain significance Single submitter
- RABGGTA p.Glu401Lys Uncertain significance Single submitter
- RABGGTA p.Glu489Gly Uncertain significance Single submitter
- RABGGTA p.His111Gln Uncertain significance Single submitter
- RABGGTA p.His467Tyr Uncertain significance Single submitter
- RABGGTA p.Leu129Val Uncertain significance Single submitter
- RABGGTA p.Lys17Glu Uncertain significance Single submitter
- RABGGTA p.Met438Leu Uncertain significance Single submitter
- RABGGTA p.Pro416Leu Uncertain significance Single submitter
- RABGGTA p.Pro479Leu Uncertain significance Single submitter
- RABGGTA p.Pro544Leu Uncertain significance Single submitter
- RABGGTA p.Ser531Phe Uncertain significance Single submitter
All RABGGTA variants
Benign 1
- p.Leu209= Multiple submitters
Uncertain significance 91
- p.Val158Met Multiple submitters ⚠
- p.Ala165Val Single submitter ⚠
- p.Ala87Ser Single submitter ⚠
- p.Arg101Gln Single submitter ⚠
- p.Arg101Trp Single submitter ⚠
- p.Arg119Cys Single submitter ⚠
- p.Arg127Pro Single submitter ⚠
- p.Arg134Cys Single submitter ⚠
- p.Arg134Leu Single submitter ⚠
- p.Arg149Gln Single submitter ⚠
- p.Arg173Gln Single submitter ⚠
- p.Arg184Cys Single submitter ⚠
- p.Arg202Cys Single submitter ⚠
- p.Arg238Gln Single submitter ⚠
- p.Arg246His Single submitter ⚠
- p.Arg252Gln Single submitter ⚠
- p.Arg263Trp Single submitter ⚠
- p.Arg270Thr Single submitter ⚠
- p.Arg293Thr Single submitter ⚠
- p.Arg295Trp Single submitter ⚠
- p.Arg337His Single submitter ⚠
- p.Arg337Leu Single submitter ⚠
- p.Arg343Gln Single submitter ⚠
- p.Arg393Trp Single submitter ⚠
- p.Arg39His Single submitter ⚠
- p.Arg418Gln Single submitter ⚠
- p.Arg426His Single submitter ⚠
- p.Arg444Cys Single submitter
- p.Arg486His Single submitter ⚠
- p.Arg509Gln Single submitter ⚠
- p.Arg509Trp Single submitter ⚠
- p.Asn124Asp Single submitter ⚠
- p.Asn124Ser Single submitter ⚠
- p.Asn310His Single submitter ⚠
- p.Asn473Ser Single submitter ⚠
- p.Asn67Thr Single submitter ⚠
- p.Asp168Asn Single submitter ⚠
- p.Asp424Glu Single submitter ⚠
- p.Asp45Val Single submitter ⚠
- p.Gln190His Single submitter ⚠
- p.Gln375Arg Single submitter ⚠
- p.Gln409fs Single submitter
- p.Gln522His Single submitter ⚠
- p.Glu339Lys Single submitter ⚠
- p.Glu369Asp Single submitter ⚠
- p.Glu401Lys Single submitter ⚠
- p.Glu43Asp Single submitter ⚠
- p.Glu442Lys Single submitter ⚠
- p.Glu489Gly Single submitter ⚠
- p.Glu77Gly Single submitter ⚠
- p.Gly268Cys Single submitter ⚠
- p.Gly503Ser Single submitter ⚠
- p.His111Gln Single submitter ⚠
- p.His182Tyr Single submitter ⚠
- p.His316Arg Single submitter ⚠
- p.His467Tyr Single submitter ⚠
- p.Ile321Ser Single submitter ⚠
- p.Ile388Val Single submitter ⚠
- p.Leu129Val Single submitter ⚠
- p.Leu236Arg Single submitter ⚠
- p.Leu405Val Single submitter ⚠
- p.Leu430Phe Single submitter ⚠
- p.Leu537Phe Single submitter ⚠
- p.Leu537Val Single submitter ⚠
- p.Leu65Phe Single submitter
- p.Lys17Glu Single submitter ⚠
- p.Met277Arg Single submitter ⚠
- p.Met438Leu Single submitter ⚠
- p.Pro282Leu Single submitter ⚠
- p.Pro314Ser Single submitter ⚠
- p.Pro416Leu Single submitter ⚠
- p.Pro479Leu Single submitter ⚠
- p.Pro523Ser Single submitter ⚠
- p.Pro544Leu Single submitter ⚠
- p.Pro82Ala Single submitter ⚠
- p.Ser531Phe Single submitter ⚠
- p.Thr289Asn Single submitter ⚠
- p.Thr317Ile Single submitter ⚠
- p.Thr346Met Single submitter ⚠
- p.Thr420Met Single submitter ⚠
- p.Thr477Ser Single submitter ⚠
- p.Trp383Ser Single submitter ⚠
- p.Tyr421Cys Single submitter ⚠
- p.Val152Met Single submitter ⚠
- p.Val332Met Single submitter ⚠
- p.Val35Ile Single submitter ⚠
- p.Val35Leu Single submitter ⚠
- p.Val414Met Single submitter ⚠
- p.Val435Met Single submitter ⚠
- p.Val455Glu Single submitter ⚠
- p.Val48Met Single submitter ⚠