RPL24 — 7 ClinVar variants
All ClinVar germline RPL24 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 6 flagged for review →
1 Likely benign · 6 Uncertain significance
Full RPL24 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 6
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 6
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- RPL24 p.Arg47Trp Uncertain significance Single submitter
- RPL24 p.Gln30His Uncertain significance Single submitter
- RPL24 p.Lys102Arg Uncertain significance Single submitter
- RPL24 p.Met127Val Uncertain significance Single submitter
- RPL24 p.Ser149Ala Uncertain significance Single submitter
- RPL24 p.Thr134Ser Uncertain significance Single submitter
All RPL24 variants
Likely benign 1
- p.Arg110= Single submitter
Uncertain significance 6
- p.Arg47Trp Single submitter ⚠
- p.Gln30His Single submitter ⚠
- p.Lys102Arg Single submitter ⚠
- p.Met127Val Single submitter ⚠
- p.Ser149Ala Single submitter ⚠
- p.Thr134Ser Single submitter ⚠