RPL32 — 9 ClinVar variants
All ClinVar germline RPL32 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 9 flagged for review →
9 Uncertain significance
Full RPL32 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 9
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 3
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
Predictors split 6
The independent predictors disagree with each other — read with care.
- RPL32 p.Arg33Cys Uncertain significance Single submitter
- RPL32 p.Arg46Ser Uncertain significance Single submitter
- RPL32 p.Arg75Gln Uncertain significance Single submitter
- RPL32 p.Arg75Trp Uncertain significance Single submitter
- RPL32 p.Asn102Asp Uncertain significance Single submitter
- RPL32 p.Lys14Arg Uncertain significance Single submitter
All RPL32 variants
Uncertain significance 9
- p.Arg33Cys Single submitter ⚠
- p.Arg46Ser Single submitter ⚠
- p.Arg75Gln Single submitter ⚠
- p.Arg75Trp Single submitter ⚠
- p.Asn102Asp Single submitter ⚠
- p.Ile58Val Single submitter ⚠
- p.Lys14Arg Single submitter ⚠
- p.Lys76Asn Single submitter ⚠
- p.Thr66Ile Single submitter ⚠