RPL36 — 14 ClinVar variants
All ClinVar germline RPL36 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 9 flagged for review →
5 Likely benign · 9 Uncertain significance
Full RPL36 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 9
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 3
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
Predictors split 6
The independent predictors disagree with each other — read with care.
- RPL36 p.Asn92Ser Uncertain significance Single submitter
- RPL36 p.His36Tyr Uncertain significance Single submitter
- RPL36 p.Ile81Val Uncertain significance Single submitter
- RPL36 p.Met58Leu Uncertain significance Single submitter
- RPL36 p.Phe72Tyr Uncertain significance Single submitter
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RPL36 p.Asn12Asp
Uncertain significance
No assertion criteria
myoepithelial tumor
All RPL36 variants
Likely benign 5
Uncertain significance 9
- p.Arg56Cys Single submitter ⚠
- p.Asn92Ser Single submitter ⚠
- p.His36Tyr Single submitter ⚠
- p.Ile81Val Single submitter ⚠
- p.Lys74Asn Single submitter ⚠
- p.Met58Leu Single submitter ⚠
- p.Phe72Tyr Single submitter ⚠
- p.Pro52Leu Single submitter ⚠
- p.Asn12Asp No assertion criteria myoepithelial tumor ⚠