STARD10 — 42 ClinVar variants
All ClinVar germline STARD10 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 39 flagged for review →
1 Benign · 41 Uncertain significance
Full STARD10 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 39
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 32
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- STARD10 p.Ala218Glu Uncertain significance Single submitter
- STARD10 p.Ala248Val Uncertain significance Single submitter
- STARD10 p.Arg134Cys Uncertain significance Single submitter
- STARD10 p.Arg134His Uncertain significance Single submitter
- STARD10 p.Arg158Trp Uncertain significance Single submitter
- STARD10 p.Arg31Ser Uncertain significance Single submitter
- STARD10 p.Asp258Glu Uncertain significance Single submitter
- STARD10 p.Asp286Glu Uncertain significance Single submitter
- STARD10 p.Asp84Tyr Uncertain significance Single submitter
- STARD10 p.Cys181Tyr Uncertain significance Single submitter
- STARD10 p.Glu20Lys Uncertain significance Single submitter
- STARD10 p.Glu282Lys Uncertain significance Single submitter
- STARD10 p.Glu36Gln Uncertain significance Single submitter
- STARD10 p.Glu38Asp Uncertain significance Single submitter
- STARD10 p.Gly18Cys Uncertain significance Single submitter
- STARD10 p.Gly18Ser Uncertain significance Single submitter
- STARD10 p.Gly281Ala Uncertain significance Single submitter
- STARD10 p.Gly281Ser Uncertain significance Single submitter
- STARD10 p.Leu247Val Uncertain significance Single submitter
- STARD10 p.Lys179Arg Uncertain significance Single submitter
- STARD10 p.Lys214Met Uncertain significance Single submitter
- STARD10 p.Pro10Ser Uncertain significance Single submitter
- STARD10 p.Pro15Ala Uncertain significance Single submitter
- STARD10 p.Pro231Ser Uncertain significance Single submitter
- STARD10 p.Pro239Leu Uncertain significance Single submitter
- STARD10 p.Ser194Phe Uncertain significance Single submitter
- STARD10 p.Ser253Leu Uncertain significance Single submitter
- STARD10 p.Ser35Ala Uncertain significance Single submitter
- STARD10 p.Thr288Pro Uncertain significance Single submitter
- STARD10 p.Thr291Asn Uncertain significance Single submitter
- STARD10 p.Thr8Ala Uncertain significance Single submitter
- STARD10 p.Val165Met Uncertain significance Single submitter
Predictors split 7
The independent predictors disagree with each other — read with care.
- STARD10 p.Asn127Ser Uncertain significance Single submitter
- STARD10 p.Asp84Asn Uncertain significance Single submitter
- STARD10 p.Gln255Leu Uncertain significance Single submitter
- STARD10 p.Gly193Ala Uncertain significance Single submitter
- STARD10 p.Ile263Thr Uncertain significance Single submitter
- STARD10 p.Leu237Pro Uncertain significance Single submitter
- STARD10 p.Lys197Thr Uncertain significance Single submitter
All STARD10 variants
Benign 1
- p.Ala267= Multiple submitters
Uncertain significance 41
- p.Ala218Glu Single submitter ⚠
- p.Ala248Val Single submitter ⚠
- p.Arg134Cys Single submitter ⚠
- p.Arg134His Single submitter ⚠
- p.Arg158Trp Single submitter ⚠
- p.Arg31Ser Single submitter ⚠
- p.Arg71Trp Single submitter
- p.Asn111Ser Single submitter
- p.Asn127Ser Single submitter ⚠
- p.Asp258Glu Single submitter ⚠
- p.Asp286Glu Single submitter ⚠
- p.Asp84Asn Single submitter ⚠
- p.Asp84Tyr Single submitter ⚠
- p.Cys181Tyr Single submitter ⚠
- p.Gln255Leu Single submitter ⚠
- p.Glu20Lys Single submitter ⚠
- p.Glu282Lys Single submitter ⚠
- p.Glu36Gln Single submitter ⚠
- p.Glu38Asp Single submitter ⚠
- p.Gly18Cys Single submitter ⚠
- p.Gly18Ser Single submitter ⚠
- p.Gly193Ala Single submitter ⚠
- p.Gly281Ala Single submitter ⚠
- p.Gly281Ser Single submitter ⚠
- p.Ile263Thr Single submitter ⚠
- p.Leu237Pro Single submitter ⚠
- p.Leu247Val Single submitter ⚠
- p.Lys179Arg Single submitter ⚠
- p.Lys197Thr Single submitter ⚠
- p.Lys214Met Single submitter ⚠
- p.Pro10Ser Single submitter ⚠
- p.Pro15Ala Single submitter ⚠
- p.Pro231Ser Single submitter ⚠
- p.Pro239Leu Single submitter ⚠
- p.Ser194Phe Single submitter ⚠
- p.Ser253Leu Single submitter ⚠
- p.Ser35Ala Single submitter ⚠
- p.Thr288Pro Single submitter ⚠
- p.Thr291Asn Single submitter ⚠
- p.Thr8Ala Single submitter ⚠
- p.Val165Met Single submitter ⚠