STK32A — 63 ClinVar variants
All ClinVar germline STK32A variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 60 flagged for review →
63 Uncertain significance
Full STK32A gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 60
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 47
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- STK32A p.Ala168Val Uncertain significance Single submitter
- STK32A p.Ala169Val Uncertain significance Single submitter
- STK32A p.Ala3Thr Uncertain significance Single submitter
- STK32A p.Ala3Val Uncertain significance Single submitter
- STK32A p.Arg109His Uncertain significance Single submitter
- STK32A p.Arg220Gln Uncertain significance Single submitter
- STK32A p.Arg226Cys Uncertain significance Single submitter
- STK32A p.Arg268Gln Uncertain significance Single submitter
- STK32A p.Arg27Gln Uncertain significance Single submitter
- STK32A p.Arg329Ser Uncertain significance Single submitter
- STK32A p.Asn377Ser Uncertain significance Single submitter
- STK32A p.Asp107Asn Uncertain significance Single submitter
- STK32A p.Asp13Gly Uncertain significance Single submitter
- STK32A p.Gln251Arg Uncertain significance Single submitter
- STK32A p.Glu252Lys Uncertain significance Single submitter
- STK32A p.Glu71Asp Uncertain significance Single submitter
- STK32A p.Gly2Ala Uncertain significance Single submitter
- STK32A p.Gly303Ser Uncertain significance Single submitter
- STK32A p.Gly77Val Uncertain significance Single submitter
- STK32A p.Ile234Thr Uncertain significance Single submitter
- STK32A p.Ile295Thr Uncertain significance Single submitter
- STK32A p.Ile39Asn Uncertain significance Single submitter
- STK32A p.Leu130Met Uncertain significance Single submitter
- STK32A p.Leu130Pro Uncertain significance Single submitter
- STK32A p.Leu257Pro Uncertain significance Single submitter
- STK32A p.Leu257Val Uncertain significance Single submitter
- STK32A p.Leu330Met Uncertain significance Single submitter
- STK32A p.Lys292Arg Uncertain significance Single submitter
- STK32A p.Lys335Asn Uncertain significance Single submitter
- STK32A p.Lys8Asn Uncertain significance Single submitter
- STK32A p.Met187Thr Uncertain significance Single submitter
- STK32A p.Met191Ile Uncertain significance Single submitter
- STK32A p.Met191Val Uncertain significance Single submitter
- STK32A p.Met337Lys Uncertain significance Single submitter
- STK32A p.Met96Arg Uncertain significance Single submitter
- STK32A p.Phe20Ser Uncertain significance Single submitter
- STK32A p.Pro246Ser Uncertain significance Single submitter
- STK32A p.Pro322Leu Uncertain significance Single submitter
- STK32A p.Pro376Gln Uncertain significance Single submitter
- STK32A p.Ser255Leu Uncertain significance Single submitter
- STK32A p.Thr212Met Uncertain significance Single submitter
- STK32A p.Thr45Ile Uncertain significance Single submitter
- STK32A p.Thr5Ala Uncertain significance Single submitter
- STK32A p.Trp87Cys Uncertain significance Single submitter
- STK32A p.Tyr88Phe Uncertain significance Single submitter
- STK32A p.Val235Ile Uncertain significance Single submitter
- STK32A p.Val289Asp Uncertain significance Single submitter
Predictors split 13
The independent predictors disagree with each other — read with care.
- STK32A p.Arg221Lys Uncertain significance Single submitter
- STK32A p.Arg329His Uncertain significance Single submitter
- STK32A p.Glu190Asp Uncertain significance Single submitter
- STK32A p.Glu262Lys Uncertain significance Single submitter
- STK32A p.Gly2Glu Uncertain significance Single submitter
- STK32A p.Leu86Val Uncertain significance Single submitter
- STK32A p.Met51Ile Uncertain significance Single submitter
- STK32A p.Met75Val Uncertain significance Single submitter
- STK32A p.Pro279Leu Uncertain significance Single submitter
- STK32A p.Ser230Phe Uncertain significance Single submitter
- STK32A p.Thr163Ala Uncertain significance Single submitter
- STK32A p.Thr179Ile Uncertain significance Single submitter
- STK32A p.Val160Met Uncertain significance Single submitter
All STK32A variants
Uncertain significance 63
- p.Ala168Val Single submitter ⚠
- p.Ala169Val Single submitter ⚠
- p.Ala3Thr Single submitter ⚠
- p.Ala3Val Single submitter ⚠
- p.Arg109His Single submitter ⚠
- p.Arg220Gln Single submitter ⚠
- p.Arg221Lys Single submitter ⚠
- p.Arg226Cys Single submitter ⚠
- p.Arg268Gln Single submitter ⚠
- p.Arg27Gln Single submitter ⚠
- p.Arg329His Single submitter ⚠
- p.Arg329Ser Single submitter ⚠
- p.Asn377Ser Single submitter ⚠
- p.Asn67Ser Single submitter
- p.Asp107Asn Single submitter ⚠
- p.Asp13Gly Single submitter ⚠
- p.Gln251Arg Single submitter ⚠
- p.Glu190Asp Single submitter ⚠
- p.Glu252Lys Single submitter ⚠
- p.Glu262Lys Single submitter ⚠
- p.Glu61Val Single submitter
- p.Glu71Asp Single submitter ⚠
- p.Gly2Ala Single submitter ⚠
- p.Gly2Glu Single submitter ⚠
- p.Gly303Ser Single submitter ⚠
- p.Gly77Val Single submitter ⚠
- p.Ile234Thr Single submitter ⚠
- p.Ile295Thr Single submitter ⚠
- p.Ile39Asn Single submitter ⚠
- p.Leu130Met Single submitter ⚠
- p.Leu130Pro Single submitter ⚠
- p.Leu257Pro Single submitter ⚠
- p.Leu257Val Single submitter ⚠
- p.Leu330Met Single submitter ⚠
- p.Leu86Val Single submitter ⚠
- p.Lys292Arg Single submitter ⚠
- p.Lys335Asn Single submitter ⚠
- p.Lys8Asn Single submitter ⚠
- p.Met187Thr Single submitter ⚠
- p.Met191Ile Single submitter ⚠
- p.Met191Val Single submitter ⚠
- p.Met337Lys Single submitter ⚠
- p.Met51Ile Single submitter ⚠
- p.Met75Val Single submitter ⚠
- p.Met96Arg Single submitter ⚠
- p.Phe20Ser Single submitter ⚠
- p.Pro246Ser Single submitter ⚠
- p.Pro279Leu Single submitter ⚠
- p.Pro322Leu Single submitter ⚠
- p.Pro376Gln Single submitter ⚠
- p.Ser230Phe Single submitter ⚠
- p.Ser255Leu Single submitter ⚠
- p.Thr163Ala Single submitter ⚠
- p.Thr179Ile Single submitter ⚠
- p.Thr212Met Single submitter ⚠
- p.Thr45Ile Single submitter ⚠
- p.Thr5Ala Single submitter ⚠
- p.Trp87Cys Single submitter ⚠
- p.Tyr88Phe Single submitter ⚠
- p.Val160Met Single submitter ⚠
- p.Val235Ile Single submitter ⚠
- p.Val289Asp Single submitter ⚠
- p.Val65Met Single submitter