TAF11 — 13 ClinVar variants
All ClinVar germline TAF11 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 13 flagged for review →
13 Uncertain significance
Full TAF11 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 13
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 12
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- TAF11 p.Ala4Thr Uncertain significance Single submitter
- TAF11 p.Ala80Thr Uncertain significance Single submitter
- TAF11 p.Arg120Cys Uncertain significance Single submitter
- TAF11 p.Arg120Ser Uncertain significance Single submitter
- TAF11 p.Glu90Lys Uncertain significance Single submitter
- TAF11 p.Glu93Asp Uncertain significance Single submitter
- TAF11 p.Gly12Ser Uncertain significance Single submitter
- TAF11 p.His5Tyr Uncertain significance Single submitter
- TAF11 p.Ile141Thr Uncertain significance Single submitter
- TAF11 p.Pro8Thr Uncertain significance Single submitter
- TAF11 p.Ser74Ala Uncertain significance Single submitter
- TAF11 p.Ser9Cys Uncertain significance Single submitter
Predictors split 1
The independent predictors disagree with each other — read with care.
All TAF11 variants
Uncertain significance 13
- p.Ala4Thr Single submitter ⚠
- p.Ala80Thr Single submitter ⚠
- p.Arg120Cys Single submitter ⚠
- p.Arg120Ser Single submitter ⚠
- p.Glu90Lys Single submitter ⚠
- p.Glu93Asp Single submitter ⚠
- p.Gly12Ser Single submitter ⚠
- p.Gly198Ala Single submitter ⚠
- p.His5Tyr Single submitter ⚠
- p.Ile141Thr Single submitter ⚠
- p.Pro8Thr Single submitter ⚠
- p.Ser74Ala Single submitter ⚠
- p.Ser9Cys Single submitter ⚠