Sugi Variant

Sugi Variant/TRAF3

TRAF3 — 394 ClinVar variants

All ClinVar germline TRAF3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 164 flagged for review →

4 Pathogenic · 1 Likely pathogenic · 8 Conflicting · 16 Benign · 6 Benign/Likely benign · 180 Likely benign · 179 Uncertain significance

Full TRAF3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 164

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 8

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 134

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.

Predictors split 22

The independent predictors disagree with each other — read with care.

All TRAF3 variants

Pathogenic 4

Likely pathogenic 1

  • p.Lys467fs Single submitter Autosomal dominant TRAF3-related disorders

Conflicting classifications of pathogenicity 8

  • p.Ala12Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala188Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg118Trp Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg150His Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg25His Single submitter TRAF3-related disorder ⚠
  • p.Arg321Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser563Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser62Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠

Benign 16

  • c.297+12T>G Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.297+19T>A Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.820-15G>T Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Pro63= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Ser370= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.245+10_245+21del Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+19C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+21C>T Single submitter
  • c.297+19dup Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.570+20A>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.727-59G>T Single submitter
  • c.727-5C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.His318= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser472= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr495= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Val408= Single submitter herpes simplex encephalitis, susceptibility to, 3

Benign/Likely benign 6

  • c.245+16C>T Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.297+19del Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Ala432= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Leu438= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Ser503= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Ser563= Multiple submitters herpes simplex encephalitis, susceptibility to, 3

Likely benign 180

  • c.1136-17del Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.652-7G>A Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.727-16A>G Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.819+16T>C Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.819+4G>A Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Arg398= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Gln258= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Glu280= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Gly243= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.His165= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Leu409= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Lys329= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Phe555= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Pro489= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Thr411= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Thr46= Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • c.1135+12G>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1135+15G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1135+17G>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1135+20C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1135+4_1135+9dup Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1135+9GGGGCC[3] Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1136-10C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1136-13T>G Single submitter
  • c.1136-15C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.1136-4G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+11T>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+12C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+14C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+17G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+17G>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+20C>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+22_245+33del Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.245+7G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.246-12_246-11del Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.246-14G>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.246-17C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.246-18A>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.297+10G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.297+11G>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.297+21dup Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.402+11A>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.402+17C>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.402+17C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.402+18A>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.402+20dup Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.402+20T>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.402+7A>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.403-14G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.403-15T>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.570+12C>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.570+18C>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.570+31_570+66del Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.570+9C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.651+18C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.651+9G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.652-18G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.652-18G>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.652-19C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.652-8C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.726+10C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.726+11G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.726+12A>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.726+16T>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.727-15T>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.727-16_727-15del Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.727-17C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.727-4G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.727-4G>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.727-7C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.819+16dup Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.820-12T>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.960+17T>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.960+19C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.960+20G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.961-11T>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.961-12T>G Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.961-13T>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.961-16A>C Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.-6C>G Single submitter
  • p.Ala12= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala125= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala169= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala188= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala256= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala371= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala400= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala90= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg25Leu Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg360= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg387= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg423= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg427= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asn261= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asn311= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asn415= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asn461= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asn517= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asp161= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asp389= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asp463= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asp551= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asp567= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Cys105= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Cys106= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Cys73= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gln183= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu167= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu271= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu332= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu527= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu74= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu93= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gly37= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gly379= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gly464= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gly466= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gly509= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gly533= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.His259= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.His395= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.His70= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ile115= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ile187= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ile337= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ile477= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ile530= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ile95= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu130= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu137= Single submitter
  • p.Leu162= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu189= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu19= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu270= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu319= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu364= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu381= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu418= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu471= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Leu543= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys181= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys235= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys249= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys286= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys315= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys436= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys55= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Met129Thr Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Phe537= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro147= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro17= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro18= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro30= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro34= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro566= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser255= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser269= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser275= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser3= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser314= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser366= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser413= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ser439= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr176= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr29= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr362= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr469= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr525= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr66= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Thr89= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Tyr237= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Tyr414= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Tyr441= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Tyr459= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Tyr51= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Tyr548= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Val100= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Val240Ile Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Val417= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Val542= Single submitter herpes simplex encephalitis, susceptibility to, 3

Uncertain significance 179

  • p.Ala188Val Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala371Thr Multiple submitters ⚠
  • p.Ala371Val Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala78Val Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala90Val Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg25Cys Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg338Gln Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg341Trp Multiple submitters herpes simplex encephalitis, susceptibility to, 3
  • p.Asn245Lys Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asn261Ser Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asp152Glu Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asp164Gly Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gln14His Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gln190Lys Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro10Leu Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro18Leu Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser26Arg Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Thr29Met Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val210Ile Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val47Met Multiple submitters herpes simplex encephalitis, susceptibility to, 3 ⚠
  • c.245+6C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.297+18_297+19inv Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.297+6del Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.403-3C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.570+4C>T Single submitter herpes simplex encephalitis, susceptibility to, 3
  • c.570+5G>A Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Ala112Thr Single submitter ⚠
  • p.Ala12Val Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala188Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala188Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala256Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala27Pro Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala371Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala375Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala412Val Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala484Thr Single submitter ⚠
  • p.Ala484Val Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala531Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala539Gly Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ala78Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg118Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg122Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg163Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg163Pro Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg163Ter Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg173Trp Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg236His Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg236Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg310Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg321Ter Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg338Trp Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg341Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg360Cys Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Arg360His Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg376Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg376Gly Single submitter ⚠
  • p.Arg376Trp Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg405His Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg423His Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg427Trp Single submitter ⚠
  • p.Arg428Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg428Trp Single submitter ⚠
  • p.Arg457fs Single submitter
  • p.Arg479Cys Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Arg479His Single submitter ⚠
  • p.Arg71His Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asn139Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asn227Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asn415Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asn545Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asp161Tyr Single submitter TRAF3-related disorder ⚠
  • p.Asp164Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asp164Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asp324fs Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Asp396Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asp401Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Asp424Asn Single submitter ⚠
  • p.Asp515Gly Single submitter ⚠
  • p.Asp551Asn Single submitter ⚠
  • p.Asp551Glu Single submitter ⚠
  • p.Asp552Asn Single submitter ⚠
  • p.Asp552Glu Single submitter ⚠
  • p.Cys124Gly Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Cys296Tyr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gln190His Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gln294Lys Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gln320= Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gln36Arg Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gln384Ter Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Gln407Ter Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu167Ala Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Glu336Asp Single submitter ⚠
  • p.Glu345Ter Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu355Ala Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Glu363Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Glu67Gln Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Glu67Lys Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gly131Arg Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gly464Arg Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Gly533Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.His132Arg Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.His142Tyr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.His165Asp Single submitter ⚠
  • p.His179Tyr Single submitter ⚠
  • p.His292Tyr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ile288Val Single submitter ⚠
  • p.Ile300Thr Single submitter ⚠
  • p.Ile477Val Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Leu162Met Single submitter ⚠
  • p.Leu330Pro Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Leu364Val Single submitter ⚠
  • p.Lys107Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys154Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys171fs Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys171Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys286fs Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Lys331Arg Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys351Gln Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys369Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys40Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys42Asn Single submitter ⚠
  • p.Lys42Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys52Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys6Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys87Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Lys99Glu Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Met129Val Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Met308Val Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Met465Ile Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Phe143Cys Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro10Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro10Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro147Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro17Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro185Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro339Ala Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro489delinsLeuProTrp Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Pro489Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro63Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser254Asn Single submitter ⚠
  • p.Ser269Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser275Phe Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser290Gly Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser349Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser366Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser370Asn Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser3Pro Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser82Arg Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser85Gly Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Ser9Thr Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Thr195Ala Single submitter ⚠
  • p.Thr231Ala Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Thr23Ala Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Thr244Ser Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Thr378Arg Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Thr469Met Single submitter ⚠
  • p.Tyr116Cys Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Tyr459Cys Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Tyr482Cys Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val135Met Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val166Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val166Met Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val210Phe Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val226Phe Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val240Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val257Met Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val260Ala Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val260Ile Single submitter ⚠
  • p.Val354Met Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val361Met Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val367Glu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val367Met Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val433Ile Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val476fs Single submitter herpes simplex encephalitis, susceptibility to, 3
  • p.Val538Leu Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Val558Asp Single submitter ⚠
  • p.Val560Met Single submitter ⚠
  • p.Val96Ile Single submitter herpes simplex encephalitis, susceptibility to, 3 ⚠
  • p.Pro18Arg No assertion criteria ependymoma ⚠