TRPM7 — 280 ClinVar variants
All ClinVar germline TRPM7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 198 flagged for review →
3 Pathogenic · 3 Conflicting · 33 Benign · 3 Benign/Likely benign · 21 Likely benign · 217 Uncertain significance
Full TRPM7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 198
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors agree, ClinVar conflicts 2
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
- TRPM7 p.Ser1193Asn Conflicting Single submitter
-
TRPM7 p.Thr1482Ile
Conflicting
Single submitter
juvenile amyotrophic lateral sclerosis
Predictors lean, ClinVar uncertain 154
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 154
- TRPM7 p.Arg197Gln Uncertain significance Multiple submitters
- TRPM7 p.Gln1523Arg Uncertain significance Multiple submitters
- TRPM7 p.His1443Tyr Uncertain significance Multiple submitters
-
TRPM7 p.His1643Arg
Uncertain significance
Multiple submitters
amyotrophic lateral sclerosis-parkinsonism-dementia complex
- TRPM7 p.Pro1841His Uncertain significance Multiple submitters
- TRPM7 p.Thr269Ser Uncertain significance Multiple submitters
-
TRPM7 p.Thr842Met
Uncertain significance
Multiple submitters
amyotrophic lateral sclerosis-parkinsonism-dementia complex
- TRPM7 p.Val496Ile Uncertain significance Multiple submitters
- TRPM7 p.Ala1033Asp Uncertain significance Single submitter
- TRPM7 p.Ala1439Val Uncertain significance Single submitter
- TRPM7 p.Ala1808Thr Uncertain significance Single submitter
- TRPM7 p.Ala181Thr Uncertain significance Single submitter
- TRPM7 p.Ala321Gly Uncertain significance Single submitter
- TRPM7 p.Ala341Thr Uncertain significance Single submitter
- TRPM7 p.Ala407Thr Uncertain significance Single submitter
- TRPM7 p.Ala74Val Uncertain significance Single submitter
- TRPM7 p.Ala950Thr Uncertain significance Single submitter
- TRPM7 p.Arg1862His Uncertain significance Single submitter
- TRPM7 p.Arg374Ser Uncertain significance Single submitter
- TRPM7 p.Arg532Cys Uncertain significance Single submitter
- TRPM7 p.Arg532His Uncertain significance Single submitter
- TRPM7 p.Arg545Gln Uncertain significance Single submitter
- TRPM7 p.Arg549Gln Uncertain significance Single submitter
- TRPM7 p.Arg559Gln Uncertain significance Single submitter
- TRPM7 p.Arg559Pro Uncertain significance Single submitter
- TRPM7 p.Arg568Gly Uncertain significance Single submitter
- TRPM7 p.Arg617Cys Uncertain significance Single submitter
- TRPM7 p.Arg639Cys Uncertain significance Single submitter
- TRPM7 p.Arg819Gln Uncertain significance Single submitter
- TRPM7 p.Arg819Trp Uncertain significance Single submitter
- TRPM7 p.Arg843Gln Uncertain significance Single submitter
-
TRPM7 p.Arg902Cys
Uncertain significance
Single submitter
amyotrophic lateral sclerosis-parkinsonism-dementia complex
- TRPM7 p.Asn1183Ser Uncertain significance Single submitter
- TRPM7 p.Asn1434Ser Uncertain significance Single submitter
- TRPM7 p.Asn1466Asp Uncertain significance Single submitter
- TRPM7 p.Asn1845Asp Uncertain significance Single submitter
- TRPM7 p.Asn240Ser Uncertain significance Single submitter
- TRPM7 p.Asn359Tyr Uncertain significance Single submitter
- TRPM7 p.Asn567Tyr Uncertain significance Single submitter
- TRPM7 p.Asn684Asp Uncertain significance Single submitter
- TRPM7 p.Asn802Ser Uncertain significance Single submitter
- TRPM7 p.Asn983Lys Uncertain significance Single submitter
- TRPM7 p.Asp1166Glu Uncertain significance Single submitter
- TRPM7 p.Asp1186Asn Uncertain significance Single submitter
- TRPM7 p.Asp1187Asn Uncertain significance Single submitter
- TRPM7 p.Asp1445Asn Uncertain significance Single submitter
- TRPM7 p.Asp1445Gly Uncertain significance Single submitter
- TRPM7 p.Asp1483Asn Uncertain significance Single submitter
- TRPM7 p.Asp1790Asn Uncertain significance Single submitter
- TRPM7 p.Asp1839Asn Uncertain significance Single submitter
- TRPM7 p.Asp570Val Uncertain significance Single submitter
- TRPM7 p.Asp798Gly Uncertain significance Single submitter
- TRPM7 p.Asp954Val Uncertain significance Single submitter
- TRPM7 p.Cys1631Arg Uncertain significance Single submitter
- TRPM7 p.Cys738Tyr Uncertain significance Single submitter
- TRPM7 p.Gln1382Lys Uncertain significance Single submitter
- TRPM7 p.Gln1408Arg Uncertain significance Single submitter
- TRPM7 p.Gln366Arg Uncertain significance Single submitter
- TRPM7 p.Gln789Lys Uncertain significance Single submitter
- TRPM7 p.Gln804His Uncertain significance Single submitter
- TRPM7 p.Gln885Glu Uncertain significance Single submitter
- TRPM7 p.Glu1164Asp Uncertain significance Single submitter
- TRPM7 p.Glu1436Lys Uncertain significance Single submitter
- TRPM7 p.Glu817Lys Uncertain significance Single submitter
- TRPM7 p.Gly100Val Uncertain significance Single submitter
- TRPM7 p.Gly1046Arg Uncertain significance Single submitter
- TRPM7 p.Gly1770Asp Uncertain significance Single submitter
- TRPM7 p.Gly292Val Uncertain significance Single submitter
- TRPM7 p.Gly483Asp Uncertain significance Single submitter
- TRPM7 p.Gly826Val Uncertain significance Single submitter
- TRPM7 p.Gly93Arg Uncertain significance Single submitter
- TRPM7 p.His1190Gln Uncertain significance Single submitter
- TRPM7 p.His1370Arg Uncertain significance Single submitter
- TRPM7 p.His1443Arg Uncertain significance Single submitter
- TRPM7 p.His1443Gln Uncertain significance Single submitter
- TRPM7 p.His562Asp Uncertain significance Single submitter
- TRPM7 p.Ile1036Thr Uncertain significance Single submitter
- TRPM7 p.Ile1134Val Uncertain significance Single submitter
- TRPM7 p.Ile1138Met Uncertain significance Single submitter
- TRPM7 p.Ile1138Val Uncertain significance Single submitter
- TRPM7 p.Ile120Val Uncertain significance Single submitter
- TRPM7 p.Ile137Thr Uncertain significance Single submitter
- TRPM7 p.Ile1459Thr Uncertain significance Single submitter
- TRPM7 p.Ile1803Val Uncertain significance Single submitter
- TRPM7 p.Ile202Val Uncertain significance Single submitter
- TRPM7 p.Ile383Val Uncertain significance Single submitter
- TRPM7 p.Ile581Val Uncertain significance Single submitter
- TRPM7 p.Ile607Thr Uncertain significance Single submitter
- TRPM7 p.Leu1141Met Uncertain significance Single submitter
- TRPM7 p.Leu1607Phe Uncertain significance Single submitter
- TRPM7 p.Leu1819Pro Uncertain significance Single submitter
- TRPM7 p.Leu288Val Uncertain significance Single submitter
- TRPM7 p.Leu324Val Uncertain significance Single submitter
- TRPM7 p.Leu713Pro Uncertain significance Single submitter
- TRPM7 p.Lys1494Ile Uncertain significance Single submitter
- TRPM7 p.Lys1616Arg Uncertain significance Single submitter
- TRPM7 p.Lys531Arg Uncertain significance Single submitter
- TRPM7 p.Lys560Asn Uncertain significance Single submitter
- TRPM7 p.Lys616Arg Uncertain significance Single submitter
- TRPM7 p.Lys651Asn Uncertain significance Single submitter
- TRPM7 p.Lys915Asn Uncertain significance Single submitter
- TRPM7 p.Met1007Val Uncertain significance Single submitter
- TRPM7 p.Met1531Val Uncertain significance Single submitter
- TRPM7 p.Met369Thr Uncertain significance Single submitter
- TRPM7 p.Met443Val Uncertain significance Single submitter
- TRPM7 p.Met796Thr Uncertain significance Single submitter
- TRPM7 p.Phe1378Leu Uncertain significance Single submitter
- TRPM7 p.Phe468Leu Uncertain significance Single submitter
- TRPM7 p.Pro1392Leu Uncertain significance Single submitter
- TRPM7 p.Pro1409Ser Uncertain significance Single submitter
- TRPM7 p.Pro1490Leu Uncertain significance Single submitter
- TRPM7 p.Pro206Ser Uncertain significance Single submitter
- TRPM7 p.Pro339Leu Uncertain significance Single submitter
- TRPM7 p.Pro487Ala Uncertain significance Single submitter
- TRPM7 p.Pro732Arg Uncertain significance Single submitter
- TRPM7 p.Ser112Ala Uncertain significance Single submitter
- TRPM7 p.Ser1155Phe Uncertain significance Single submitter
- TRPM7 p.Ser1427Pro Uncertain significance Single submitter
- TRPM7 p.Ser1493Pro Uncertain significance Single submitter
- TRPM7 p.Ser1500Gly Uncertain significance Single submitter
- TRPM7 p.Ser307Arg Uncertain significance Single submitter
- TRPM7 p.Ser307Ile Uncertain significance Single submitter
- TRPM7 p.Ser744Phe Uncertain significance Single submitter
- TRPM7 p.Thr1031Ile Uncertain significance Single submitter
- TRPM7 p.Thr1417Ser Uncertain significance Single submitter
- TRPM7 p.Thr1455Ile Uncertain significance Single submitter
- TRPM7 p.Thr1467Ile Uncertain significance Single submitter
- TRPM7 p.Thr1537Ala Uncertain significance Single submitter
- TRPM7 p.Thr1685Met Uncertain significance Single submitter
- TRPM7 p.Thr1741Ala Uncertain significance Single submitter
- TRPM7 p.Thr397Ile Uncertain significance Single submitter
- TRPM7 p.Thr551Ile Uncertain significance Single submitter
- TRPM7 p.Thr84Ala Uncertain significance Single submitter
- TRPM7 p.Thr84Ile Uncertain significance Single submitter
- TRPM7 p.Thr871Ile Uncertain significance Single submitter
- TRPM7 p.Trp1658Cys Uncertain significance Single submitter
- TRPM7 p.Tyr1002Cys Uncertain significance Single submitter
- TRPM7 p.Tyr1023His Uncertain significance Single submitter
- TRPM7 p.Tyr1116Cys Uncertain significance Single submitter
- TRPM7 p.Tyr1181Cys Uncertain significance Single submitter
- TRPM7 p.Tyr225Cys Uncertain significance Single submitter
- TRPM7 p.Tyr505Cys Uncertain significance Single submitter
- TRPM7 p.Tyr505His Uncertain significance Single submitter
- TRPM7 p.Tyr537His Uncertain significance Single submitter
- TRPM7 p.Val1511Ala Uncertain significance Single submitter
- TRPM7 p.Val1575Met Uncertain significance Single submitter
- TRPM7 p.Val300Ile Uncertain significance Single submitter
- TRPM7 p.Val636Phe Uncertain significance Single submitter
- TRPM7 p.Val691Ile Uncertain significance Single submitter
- TRPM7 p.Val761Ile Uncertain significance Single submitter
Predictors split 42
The independent predictors disagree with each other — read with care.
-
TRPM7 p.Lys714Thr
Uncertain significance
Multiple submitters
amyotrophic lateral sclerosis-parkinsonism-dementia complex
- TRPM7 p.Ala1057Thr Uncertain significance Single submitter
- TRPM7 p.Ala1121Pro Uncertain significance Single submitter
- TRPM7 p.Ala1557Thr Uncertain significance Single submitter
- TRPM7 p.Arg1198His Uncertain significance Single submitter
- TRPM7 p.Cys1671Ser Uncertain significance Single submitter
- TRPM7 p.Glu302Lys Uncertain significance Single submitter
- TRPM7 p.Gly1438Arg Uncertain significance Single submitter
- TRPM7 p.Gly1622Arg Uncertain significance Single submitter
-
TRPM7 p.His577Tyr
Uncertain significance
Single submitter
amyotrophic lateral sclerosis-parkinsonism-dementia complex
- TRPM7 p.Ile1021Met Uncertain significance Single submitter
- TRPM7 p.Ile1044Val Uncertain significance Single submitter
- TRPM7 p.Ile1053Val Uncertain significance Single submitter
-
TRPM7 p.Ile932Val
Uncertain significance
Single submitter
amyotrophic lateral sclerosis-parkinsonism-dementia complex
- TRPM7 p.Leu1684Phe Uncertain significance Single submitter
- TRPM7 p.Leu304Phe Uncertain significance Single submitter
- TRPM7 p.Lys1034Glu Uncertain significance Single submitter
- TRPM7 p.Lys126Glu Uncertain significance Single submitter
- TRPM7 p.Lys1616Asn Uncertain significance Single submitter
- TRPM7 p.Lys467Thr Uncertain significance Single submitter
- TRPM7 p.Met1000Thr Pathogenic Single submitter
- TRPM7 p.Met465Val Uncertain significance Single submitter
- TRPM7 p.Met649Leu Uncertain significance Single submitter
- TRPM7 p.Met868Ile Uncertain significance Single submitter
- TRPM7 p.Phe1095Leu Uncertain significance Single submitter
- TRPM7 p.Phe1189Leu Uncertain significance Single submitter
- TRPM7 p.Phe1440Ser Uncertain significance Single submitter
- TRPM7 p.Phe1717Cys Uncertain significance Single submitter
- TRPM7 p.Phe845Cys Uncertain significance Single submitter
- TRPM7 p.Phe939Leu Uncertain significance Single submitter
- TRPM7 p.Pro117Ser Uncertain significance Single submitter
- TRPM7 p.Pro472Leu Uncertain significance Single submitter
- TRPM7 p.Pro502Thr Uncertain significance Single submitter
- TRPM7 p.Ser1712Leu Uncertain significance Single submitter
- TRPM7 p.Tyr1085His Uncertain significance Single submitter
- TRPM7 p.Val139Leu Uncertain significance Single submitter
- TRPM7 p.Val1719Ala Uncertain significance Single submitter
- TRPM7 p.Val221Gly Uncertain significance Single submitter
- TRPM7 p.Val286Met Uncertain significance Single submitter
- TRPM7 p.Val314Leu Uncertain significance Single submitter
- TRPM7 p.Arg975His Uncertain significance No assertion criteria
- TRPM7 p.Trp887Arg Uncertain significance No assertion criteria
All TRPM7 variants
Pathogenic 3
- p.Leu1081Arg Single submitter
- p.Met1000Thr Single submitter ⚠
- p.Gly1046Asp No assertion criteria intestinal hypomagnesemia 1
Conflicting classifications of pathogenicity 3
- p.Leu1092del Single submitter
- p.Ser1193Asn Single submitter ⚠
- p.Thr1482Ile Single submitter juvenile amyotrophic lateral sclerosis ⚠
Benign 33
- c.1131+3A>G Multiple submitters amyotrophic lateral sclerosis-parkinsonism-dementia complex
- c.1131+71C>T Multiple submitters
- c.2437-9del Multiple submitters
- c.3164-41T>A Multiple submitters
- c.3476-30C>A Multiple submitters
- c.4486+111C>T Multiple submitters
- c.*304T>C Multiple submitters
- p.Asn1058= Multiple submitters
- p.Phe979= Multiple submitters
- p.Tyr1662= Multiple submitters
- c.1007+246G>C Single submitter
- c.1007+32ATTT[5] Single submitter
- c.1205-170G>A Single submitter
- c.1440+265T>C Single submitter
- c.1441-297T>C Single submitter
- c.1441-310A>G Single submitter
- c.1770+124C>T Single submitter
- c.3290+277A>T Single submitter
- c.3291-162T>G Single submitter
- c.3475+133G>A Single submitter
- c.3476-253C>G Single submitter
- c.535+230C>T Single submitter
- c.5360+4A>G Single submitter
- c.660+191T>A Single submitter
- c.660+198C>A Single submitter
- c.660+21T>G Single submitter
- p.Ile75Val Single submitter
- p.Ser1463= Single submitter
- c.1635+4T>C No assertion criteria TRPM7-related disorder
- p.Gly1642= No assertion criteria TRPM7-related disorder
- p.Ser1500del No assertion criteria TRPM7-related disorder
- p.Ser1660Asn No assertion criteria TRPM7-related disorder
- p.Tyr1756= No assertion criteria TRPM7-related disorder
Benign/Likely benign 3
- c.536-4A>G Multiple submitters
- p.Asp495= Multiple submitters
- p.Phe949Tyr Multiple submitters
Likely benign 21
- p.Ile1647= Multiple submitters
- p.Leu1708= Multiple submitters
- c.1636-13A>G Single submitter
- c.5019+9C>T Single submitter
- c.5309-10A>T Single submitter
- c.5309-5T>C Single submitter
- p.Ala1496Val Single submitter
- p.Ala74Thr Single submitter
- p.Asn1466Ser Single submitter
- p.Asn1593Ser Single submitter
- p.Asn359Ser Single submitter
- p.Asp1421Gly Single submitter
- p.His1025Arg Single submitter
- p.Ile627= Single submitter
- p.Ile75Leu Single submitter
- p.Leu228= Single submitter
- p.Leu229= Single submitter
- p.Leu298= Single submitter
- p.Pro339= Single submitter
- p.Ser1361= Single submitter
- p.Thr1657= Single submitter
Uncertain significance 217
- p.Arg197Gln Multiple submitters ⚠
- p.Gln1523Arg Multiple submitters ⚠
- p.His1443Tyr Multiple submitters ⚠
- p.His1643Arg Multiple submitters amyotrophic lateral sclerosis-parkinsonism-dementia complex ⚠
- p.Lys714Thr Multiple submitters amyotrophic lateral sclerosis-parkinsonism-dementia complex ⚠
- p.Pro1841His Multiple submitters ⚠
- p.Thr269Ser Multiple submitters ⚠
- p.Thr842Met Multiple submitters amyotrophic lateral sclerosis-parkinsonism-dementia complex ⚠
- p.Val496Ile Multiple submitters ⚠
- c.4324+5G>A Single submitter
- c.4557+18A>G Single submitter
- c.4592_4592+6dup Single submitter
- c.5361-4A>G Single submitter
- p.Ala1033Asp Single submitter ⚠
- p.Ala1057Thr Single submitter ⚠
- p.Ala1121Pro Single submitter ⚠
- p.Ala1439Val Single submitter ⚠
- p.Ala1557Thr Single submitter ⚠
- p.Ala1808Thr Single submitter ⚠
- p.Ala181Thr Single submitter ⚠
- p.Ala321Gly Single submitter ⚠
- p.Ala341Thr Single submitter ⚠
- p.Ala407Thr Single submitter ⚠
- p.Ala74Val Single submitter ⚠
- p.Ala950Thr Single submitter ⚠
- p.Arg1198His Single submitter ⚠
- p.Arg1444_Asp1445insTer Single submitter
- p.Arg1862His Single submitter ⚠
- p.Arg374Ser Single submitter ⚠
- p.Arg532Cys Single submitter ⚠
- p.Arg532His Single submitter ⚠
- p.Arg545Gln Single submitter ⚠
- p.Arg549Gln Single submitter ⚠
- p.Arg559Gln Single submitter ⚠
- p.Arg559Pro Single submitter ⚠
- p.Arg568Gly Single submitter ⚠
- p.Arg617Cys Single submitter ⚠
- p.Arg639Cys Single submitter ⚠
- p.Arg819Gln Single submitter ⚠
- p.Arg819Trp Single submitter ⚠
- p.Arg843Gln Single submitter ⚠
- p.Arg902Cys Single submitter amyotrophic lateral sclerosis-parkinsonism-dementia complex ⚠
- p.Asn1183Ser Single submitter ⚠
- p.Asn1434Ser Single submitter ⚠
- p.Asn1466Asp Single submitter ⚠
- p.Asn1774fs Single submitter
- p.Asn1845Asp Single submitter ⚠
- p.Asn240Ser Single submitter ⚠
- p.Asn359Tyr Single submitter ⚠
- p.Asn567Tyr Single submitter ⚠
- p.Asn684Asp Single submitter ⚠
- p.Asn715Ser Single submitter
- p.Asn802Ser Single submitter ⚠
- p.Asn824fs Single submitter TRPM7-associated neuropathological disorder
- p.Asn983Lys Single submitter ⚠
- p.Asn999Ser Single submitter
- p.Asp1166Glu Single submitter ⚠
- p.Asp1186Asn Single submitter ⚠
- p.Asp1187Asn Single submitter ⚠
- p.Asp1445Asn Single submitter ⚠
- p.Asp1445Gly Single submitter ⚠
- p.Asp1483Asn Single submitter ⚠
- p.Asp1790Asn Single submitter ⚠
- p.Asp1839Asn Single submitter ⚠
- p.Asp570Tyr Single submitter
- p.Asp570Val Single submitter ⚠
- p.Asp798Gly Single submitter ⚠
- p.Asp954Val Single submitter ⚠
- p.Cys1631Arg Single submitter ⚠
- p.Cys1671Ser Single submitter ⚠
- p.Cys738Tyr Single submitter ⚠
- p.Gln1077Ter Single submitter
- p.Gln1252Ter Single submitter
- p.Gln1382Lys Single submitter ⚠
- p.Gln1408Arg Single submitter ⚠
- p.Gln366Arg Single submitter ⚠
- p.Gln789Lys Single submitter ⚠
- p.Gln804His Single submitter ⚠
- p.Gln885Glu Single submitter ⚠
- p.Glu1164Asp Single submitter ⚠
- p.Glu1436Lys Single submitter ⚠
- p.Glu302Lys Single submitter ⚠
- p.Glu376Lys Single submitter
- p.Glu817Lys Single submitter ⚠
- p.Gly100Val Single submitter ⚠
- p.Gly1046Arg Single submitter ⚠
- p.Gly1438Arg Single submitter ⚠
- p.Gly1622Arg Single submitter ⚠
- p.Gly1770Asp Single submitter ⚠
- p.Gly292Val Single submitter ⚠
- p.Gly483Asp Single submitter ⚠
- p.Gly826Val Single submitter ⚠
- p.Gly93Arg Single submitter ⚠
- p.His1190Gln Single submitter ⚠
- p.His1370Arg Single submitter ⚠
- p.His1443Arg Single submitter ⚠
- p.His1443Gln Single submitter ⚠
- p.His562Asp Single submitter ⚠
- p.His577Tyr Single submitter amyotrophic lateral sclerosis-parkinsonism-dementia complex ⚠
- p.Ile1021Met Single submitter ⚠
- p.Ile1036Thr Single submitter ⚠
- p.Ile1044Val Single submitter ⚠
- p.Ile1053Val Single submitter ⚠
- p.Ile1134Val Single submitter ⚠
- p.Ile1138Met Single submitter ⚠
- p.Ile1138Val Single submitter ⚠
- p.Ile120Val Single submitter ⚠
- p.Ile137Thr Single submitter ⚠
- p.Ile1459Thr Single submitter ⚠
- p.Ile1803Met Single submitter
- p.Ile1803Val Single submitter ⚠
- p.Ile202Val Single submitter ⚠
- p.Ile383Val Single submitter ⚠
- p.Ile581Val Single submitter ⚠
- p.Ile607Thr Single submitter ⚠
- p.Ile932Val Single submitter amyotrophic lateral sclerosis-parkinsonism-dementia complex ⚠
- p.Leu1141Met Single submitter ⚠
- p.Leu1384Ter Single submitter
- p.Leu1607Phe Single submitter ⚠
- p.Leu1684Phe Single submitter ⚠
- p.Leu1819Pro Single submitter ⚠
- p.Leu288Val Single submitter ⚠
- p.Leu304Phe Single submitter ⚠
- p.Leu324Val Single submitter ⚠
- p.Leu713Pro Single submitter ⚠
- p.Lys1034Glu Single submitter ⚠
- p.Lys126Glu Single submitter ⚠
- p.Lys1494Ile Single submitter ⚠
- p.Lys1616Arg Single submitter ⚠
- p.Lys1616Asn Single submitter ⚠
- p.Lys467Thr Single submitter ⚠
- p.Lys531Arg Single submitter ⚠
- p.Lys560Asn Single submitter ⚠
- p.Lys616Arg Single submitter ⚠
- p.Lys651Asn Single submitter ⚠
- p.Lys844Gln Single submitter
- p.Lys915Asn Single submitter ⚠
- p.Met1007Val Single submitter ⚠
- p.Met1531Val Single submitter ⚠
- p.Met1748Val Single submitter
- p.Met369Thr Single submitter ⚠
- p.Met443Val Single submitter ⚠
- p.Met465Val Single submitter ⚠
- p.Met649Leu Single submitter ⚠
- p.Met796Thr Single submitter ⚠
- p.Met868Ile Single submitter ⚠
- p.Phe1095Leu Single submitter ⚠
- p.Phe1189Leu Single submitter ⚠
- p.Phe1378Leu Single submitter ⚠
- p.Phe1440Ser Single submitter ⚠
- p.Phe1717Cys Single submitter ⚠
- p.Phe468Leu Single submitter ⚠
- p.Phe845Cys Single submitter ⚠
- p.Phe939Leu Single submitter ⚠
- p.Pro117Ser Single submitter ⚠
- p.Pro1392Leu Single submitter ⚠
- p.Pro1409Ser Single submitter ⚠
- p.Pro1490Leu Single submitter ⚠
- p.Pro1519= Single submitter
- p.Pro1592Leu Single submitter
- p.Pro206Ser Single submitter ⚠
- p.Pro339Leu Single submitter ⚠
- p.Pro472Leu Single submitter ⚠
- p.Pro487Ala Single submitter ⚠
- p.Pro502Thr Single submitter ⚠
- p.Pro732Arg Single submitter ⚠
- p.Ser112Ala Single submitter ⚠
- p.Ser1155Phe Single submitter ⚠
- p.Ser1427Pro Single submitter ⚠
- p.Ser1493Pro Single submitter ⚠
- p.Ser1500Gly Single submitter ⚠
- p.Ser1712Leu Single submitter ⚠
- p.Ser193Phe Single submitter
- p.Ser307Arg Single submitter ⚠
- p.Ser307Ile Single submitter ⚠
- p.Ser744Phe Single submitter ⚠
- p.Thr1031Ile Single submitter ⚠
- p.Thr1417Ser Single submitter ⚠
- p.Thr1455Ile Single submitter ⚠
- p.Thr1467Ile Single submitter ⚠
- p.Thr1537Ala Single submitter ⚠
- p.Thr1685Met Single submitter ⚠
- p.Thr1741Ala Single submitter ⚠
- p.Thr227Ser Single submitter
- p.Thr397Ile Single submitter ⚠
- p.Thr551Ile Single submitter ⚠
- p.Thr84Ala Single submitter ⚠
- p.Thr84Ile Single submitter ⚠
- p.Thr871Ile Single submitter ⚠
- p.Trp1658Cys Single submitter ⚠
- p.Tyr1002Cys Single submitter ⚠
- p.Tyr1023His Single submitter ⚠
- p.Tyr1085His Single submitter ⚠
- p.Tyr1100Ter Single submitter
- p.Tyr1116Cys Single submitter ⚠
- p.Tyr1181Cys Single submitter ⚠
- p.Tyr225Cys Single submitter ⚠
- p.Tyr505Cys Single submitter ⚠
- p.Tyr505His Single submitter ⚠
- p.Tyr537His Single submitter ⚠
- p.Val139Leu Single submitter ⚠
- p.Val1511Ala Single submitter ⚠
- p.Val1575Met Single submitter ⚠
- p.Val1719Ala Single submitter ⚠
- p.Val221Gly Single submitter ⚠
- p.Val286Met Single submitter ⚠
- p.Val300Ile Single submitter ⚠
- p.Val314Leu Single submitter ⚠
- p.Val636Phe Single submitter ⚠
- p.Val691Ile Single submitter ⚠
- p.Val761Ile Single submitter ⚠
- p.Val814Leu Single submitter ⚠
- p.Val959Leu Single submitter ⚠
- p.Arg975His No assertion criteria ⚠
- p.Cys721Gly No assertion criteria ⚠
- p.Met1531Arg No assertion criteria ⚠
- p.Trp887Arg No assertion criteria ⚠