WIZ — 137 ClinVar variants

All ClinVar germline WIZ variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.

6 Likely benign · 131 Uncertain significance

Full WIZ gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

All WIZ variants

Likely benign 6

c.2741-1430C>T Single submitter
p.Arg609Trp Single submitter
p.Pro1227= Single submitter
p.Ser1501= Single submitter
p.Ser1713Gly Single submitter
p.Val1545Met Single submitter

Uncertain significance 131

p.Ala1278Pro Single submitter
p.Ala1300Val Single submitter
p.Ala1431Thr Single submitter
p.Ala1445Ser Single submitter
p.Ala1525Val Single submitter
p.Ala1533Val Single submitter
p.Ala1541Thr Single submitter
p.Ala1555Ser Single submitter
p.Ala1580Pro Single submitter
p.Ala1654Thr Single submitter
p.Ala1741Gly Single submitter
p.Ala1754Thr Single submitter
p.Ala1785Thr Single submitter
p.Ala1786Thr Single submitter
p.Ala1786Val Single submitter
p.Ala1878Val Single submitter
p.Ala1884Ser Single submitter
p.Ala1884Val Single submitter
p.Ala1888Ser Single submitter
p.Ala836Thr Single submitter
p.Arg1279Gly Single submitter
p.Arg1282His Single submitter
p.Arg1323Trp Single submitter
p.Arg1329Gln Single submitter
p.Arg1333Gln Single submitter
p.Arg1364Cys Single submitter
p.Arg1364Gly Single submitter
p.Arg1364His Single submitter
p.Arg1420Gln Single submitter
p.Arg1425Gln Single submitter
p.Arg1458Gln Single submitter
p.Arg1458Trp Single submitter
p.Arg1463Cys Single submitter
p.Arg1507Gln Single submitter
p.Arg1557Gln Single submitter
p.Arg1557Trp Single submitter
p.Arg1595Trp Single submitter
p.Arg1601His Single submitter
p.Arg1705His Single submitter
p.Arg1716Gln Single submitter
p.Arg1731His Single submitter
p.Arg1743Trp Single submitter
p.Arg1767Gln Single submitter
p.Arg1775Cys Single submitter
p.Arg1779Cys Single submitter
p.Arg1787Trp Single submitter
p.Arg1803Trp Single submitter
p.Arg1810Gln Single submitter
p.Arg1859Gly Single submitter
p.Arg1859Trp Single submitter
p.Arg45Trp Single submitter
p.Arg58Gln Single submitter
p.Arg58Gly Single submitter
p.Arg841His Single submitter
p.Arg876Gly Single submitter
p.Asp1714Glu Single submitter
p.Asp1746Asn Single submitter
p.Asp827Asn Single submitter
p.Gln1418His Single submitter
p.Gln1546Arg Single submitter bladder exstrophy-epispadias-cloacal exstrophy complex
p.Gln1882Arg Single submitter
p.Glu1284Gln Single submitter
p.Glu1284Lys Single submitter
p.Glu1311Gln Single submitter
p.Glu1749Gly Single submitter
p.Gly1274Ser Single submitter
p.Gly1471Ser Single submitter
p.Gly1696Asp Single submitter
p.Gly1697Ser Single submitter
p.Gly1725Asp Single submitter
p.Gly1730Ser Single submitter
p.Gly42Asp Single submitter
p.Gly65Val Single submitter
p.His1370Pro Single submitter
p.His1433Pro Single submitter
p.Ile1861Val Single submitter
p.Leu1348Val Single submitter
p.Leu1386Pro Single submitter
p.Leu1588Pro Single submitter
p.Leu1815Val Single submitter
p.Leu990Pro Single submitter
p.Lys1400Arg Single submitter
p.Lys1686Arg Single submitter
p.Met1351Thr Single submitter
p.Phe821Ile Single submitter
p.Pro12Thr Single submitter
p.Pro1334Ser Single submitter
p.Pro1337Leu Single submitter
p.Pro1345Ser Single submitter
p.Pro1373Ser Single submitter
p.Pro1379Leu Single submitter
p.Pro1379Ser Single submitter
p.Pro1380Arg Single submitter
p.Pro1382Leu Single submitter
p.Pro1396Ser Single submitter
p.Pro1429Leu Single submitter
p.Pro1524Leu Single submitter
p.Pro1550Leu Single submitter
p.Pro1553Leu Single submitter
p.Pro1553Ser Single submitter
p.Pro1596Thr Single submitter
p.Pro1717Leu Single submitter
p.Pro1756Leu Single submitter
p.Pro1780Ser Single submitter
p.Pro1806Ala Single submitter
p.Pro1813Ser Single submitter
p.Pro1819Arg Single submitter
p.Pro1872Ala Single submitter
p.Pro1872Gln Single submitter
p.Pro1872Leu Single submitter
p.Pro1872Ser Single submitter
p.Pro1873Ser Single submitter
p.Pro1879Ser Single submitter
p.Pro24Leu Single submitter
p.Ser1365Thr Single submitter
p.Ser1514Cys Single submitter
p.Ser1552Leu Single submitter
p.Ser1573Gly Single submitter
p.Ser1677Asn Single submitter
p.Ser1867Cys Single submitter
p.Thr1391Pro Single submitter
p.Thr1575Met Single submitter
p.Thr813Ala Single submitter
p.Thr902Asn Single submitter
p.Tyr1690Cys Single submitter
p.Tyr49His Single submitter
p.Val1314Ile Single submitter
p.Val1668Ile Single submitter
p.Val1729Gly Single submitter
p.Val1812Gly Single submitter
p.Val1841Leu Single submitter