PDLIM3 c.(?_1
Uncertain significance
Single submitter
Classification
Uncertain significance
ClinVar
Review
Single submitter ★☆☆☆
ClinVar · 1 submitter
gnomAD v4.1
Rare
Computational evidence
| Protein change | ||
| Missense predictors do not apply to this variant type. |
Variant & gene context
- Gene
- PDLIM3
- Coding
- c.(?_1
- MANE Select
- NM_014476
- Type
- Deletion
- Gene constraint
- LOEUF 1.071 · pLI <0.01 (gnomAD)
- Structure
- AlphaFold pLDDT 66.98
Similar variants
- PDLIM3 c.519-1906_519-1871del Uncertain significance ★ same type
- PDLIM3 c.60_93+59del Uncertain significance ★ same type
- PDLIM3 c.794-9_794-6del Uncertain significance ★ same type
- PDLIM3 c.93+2_93+4del Uncertain significance ★ same type
- PDLIM3 p.Ala225fs Uncertain significance ★ same type
- PDLIM3 p.Ala269fs Uncertain significance ★ same type
- PDLIM3 p.Gln289fs Uncertain significance ★ same type
- PDLIM3 p.Glu106fs Uncertain significance ★ same type
Built on 18 open, versioned datasets — ClinVar, gnomAD, AlphaMissense, REVEL, ClinGen & more — plus Sugi Variant's own cross-source analysis. Source data 2026-01–2026-10, ClinVar 2026-10. Full sources & versions →
Cite Sugi Variant
Gür T. Sugi Variant: A Deterministic Per-Variant Germline Reference from a Knowledge Graph for Humans and AI Agents. 2026. doi:10.5281/zenodo.21509445. This variant: https://sugi.bio/variant/pdlim3-c-1 (accessed [today's date]).
Preprint & method: sugi.bio/variant/method Machine-readable: this page as Markdown