SCHEMBL10000017

SCHEMBL10000017

CC(C)(C)OC(=O)C=C1CCC2(CC1)OCCO2

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
ELANE P08246 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1188054 0.82 KMT2A (0.37) ALDH1A1POLB
SCHEMBL8263593 0.81 USP2 (0.32)
SCHEMBL1931528 0.79 ELANE (0.38) ELANE
SCHEMBL15628167 0.79 ELANE (0.38) ELANE
SCHEMBL7300563 0.78 USP2 (0.41) ELANE
SCHEMBL337729 0.78 ESR2 (0.45) ALDH1A1POLB
SCHEMBL13327433 0.78 ALDH1A1 (0.33) ALDH1A1POLB
SCHEMBL7299181 0.76 ELANE (0.36) ELANE
SCHEMBL1931297 0.76 ELANE (0.36) ELANE
SCHEMBL19596003 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470958-B1 Antibiotic-bound poly(caprolactone) polymer UNIVERSITY OF SOUTH FLORIDA (US) 2013-06-25 US disclosed
US-20130150550-A1 Antibiotic-Bound Poly(Caprolactone) Polymer UNIVERSITY OF SOUTH FLORIDA (US) 2013-06-13 US disclosed
US-8110678-B2 Antibiotic-bound poly(caprolactone) polymer UNIVERSITY OF SOUTH FLORIDA (US) 2012-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130150550-A1 Antibiotic-Bound Poly(Caprolactone) Polymer CAPG, PGLS, GNE ALDH1A1 2039/4885POLB 1729/4885ELANE 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.