SCHEMBL10000192

SCHEMBL10000192

Cc1nnc(C)c(-c2ncc(Cl)cc2Cl)c1-c1ccc(F)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.37
SRC P12931 2/20 0.37
BRAF P15056 2/20 0.37
KDR P35968 2/20 0.37
RIPK2 O43353 1/20 0.37
EGFR P00533 1/20 0.37
TNK2 Q07912 1/20 0.37
PTK6 Q13882 1/20 0.37
MINK1 Q8N4C8 1/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
TP53 P04637 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
PTGS1 P23219 2/20 0.36
PTGS2 P35354 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK13 O15264 1/20 0.36
GCGR P47871 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000738 0.93 CNR2 (0.35) CNR2SRCBRAFKDRRIPK2
SCHEMBL10000171 0.91 SRC (0.34) CNR2SRCBRAFKDRRIPK2
SCHEMBL10019353 0.89 MEN1 (0.36) CNR2SRCBRAFKDRRIPK2
SCHEMBL10019182 0.86 AR (0.34) SRCBRAFKDRRIPK2EGFR
SCHEMBL896318 0.83 CNR2 (0.37) CNR2RAB9ANPC1KDM4EPTGS1
SCHEMBL10000169 0.81 TYMP (0.38) KDRTP53PTGS1PTGS2MEN1
SCHEMBL10000761 0.79 MAOB (0.40) CNR2SMN1; SMN2KDM4EPTGS1PTGS2
SCHEMBL3609800 0.77 PTGS2 (0.43) CNR2PTGS1PTGS2MAPK14CRHR1
SCHEMBL3604528 0.77 CNR2 (0.38) CNR2KDRRAB9ANPC1KDM4E
SCHEMBL896631 0.76 PTGS2 (0.36) RAB9AKDM4EPTGS1PTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020775-A1 PLANT DISEASE CONTROL COMPOSITION AND APPLICATION FOR SAME 住友化学株式会社 (JP) 2012-02-16 WO disclosed