SCHEMBL10000300

SCHEMBL10000300

CCCCN(CCCC)c1ccc(N=C2C=C(NC(C)=O)C(=O)C(Cl)=C2CC)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.32
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30
KDR P35968 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
MMP14 P50281 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17342958 0.92 MAPT (0.32) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL17342955 0.91 POLB (0.35) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL10000298 0.88 MAPT (0.35) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL10000295 0.87 EGFR (0.34) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL10000294 0.83 MAPT (0.33) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL10025546 0.83 ALDH1A1 (0.30) ALDH1A1
SCHEMBL12764844 0.82 POLB (0.36) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL21665465 0.82 POLB (0.36) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL14551385 0.82
SCHEMBL10000297 0.82 POLB (0.36) MAPTALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093181-B2 Thermal transfer member, thermal transfer member set, and recording method SONY CORPORATION (JP) 2012-01-10 US disclosed
US-20090186172-A1 THERMAL TRANSFER MEMBER, THERMAL TRANSFER MEMBER SET, AND RECORDING METHOD SONY CORPORATION (JP) 2009-07-23 US disclosed