SCHEMBL10000294

SCHEMBL10000294

CCCCN(CCCC)c1ccc(N=C2C=C(NC(C)=O)C(=O)C=C2C)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
MMP14 P50281 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDR P35968 1/20 0.32
AR P10275 1/20 0.31
CNR2 P34972 1/20 0.30
SLC16A3 O15427 1/20 0.30
SLC16A1 P53985 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000296 0.94 MEN1 (0.33) MAPTMEN1KMT2APOLBNPC1
SCHEMBL13206444 0.90 MAPT (0.36) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL92422 0.90 MAPT (0.36) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL11308355 0.84 MAPT (0.36) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL17342958 0.83 MAPT (0.32) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL10000300 0.83 MAPT (0.32) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL14029035 0.79 MAPT (0.41) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL11414969 0.78 MAPT (0.36) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL14047384 0.76 MAPT (0.40) MAPTALDH1A1MEN1KMT2APOLB
SCHEMBL23922076 0.76 ALDH1A1 (0.33) MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093181-B2 Thermal transfer member, thermal transfer member set, and recording method SONY CORPORATION (JP) 2012-01-10 US disclosed
US-20090186172-A1 THERMAL TRANSFER MEMBER, THERMAL TRANSFER MEMBER SET, AND RECORDING METHOD SONY CORPORATION (JP) 2009-07-23 US disclosed