SCHEMBL10000351

SCHEMBL10000351

C=CC(=O)OCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OC)cc3)c(C)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.44
L3MBTL1 Q9Y468 4/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
GBA1 P04062 1/20 0.41
MAPT P10636 6/20 0.41
GAA P10253 2/20 0.41
TP53 P04637 2/20 0.40
THRB P10828 2/20 0.39
CYP3A4 P08684 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2C19 P33261 1/20 0.39
RAB9A P51151 1/20 0.39
GFER P55789 1/20 0.39
MEN1 O00255 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HPGD P15428 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906564 0.96 MAPT (0.38) KMT2AL3MBTL1GBA1MAPTTHRB
SCHEMBL25009119 0.94 KMT2A (0.39) KMT2AL3MBTL1GBA1MAPTTHRB
SCHEMBL12434513 0.93 THRB (0.41) KMT2AL3MBTL1GBA1MAPTTHRB
SCHEMBL15583458 0.92 PPARG (0.38) KMT2AGBA1MAPTTP53THRB
SCHEMBL15397356 0.91 THRB (0.40) KMT2AL3MBTL1MAPTTP53THRB
SCHEMBL12154337 0.91 L3MBTL1 (0.38) KMT2AL3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL5961817 0.90 KMT2A (0.39) KMT2AL3MBTL1GBA1MAPTGAA
SCHEMBL26037671 0.89 KMT2A (0.43) KMT2AL3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL17244999 0.89 MAPT (0.41) KMT2AL3MBTL1CYP1A2CYP2C9MAPT
SCHEMBL12742909 0.89 KMT2A (0.40) KMT2AL3MBTL1GBA1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8094263-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-20100053509-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed