Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 17/20 | 0.73 |
| ▸ | GRM4 | Q14833 | 17/20 | 0.73 |
| ▸ | GRM6 | O15303 | 11/20 | 0.58 |
| ▸ | GRM7 | Q14831 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000480 | 0.89 | GRM8 (0.72) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000473 | 0.85 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000482 | 0.79 | GRM8 (0.72) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000478 | 0.76 | GRM8 (0.72) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL16473702 | 0.76 | GRM8 (0.56) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000479 | 0.76 | GRM8 (0.69) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL21433290 | 0.74 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL4091094 | 0.74 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000472 | 0.74 | GRM8 (1.00) | GRM8GRM4GRM6GRM7 | |
| SCHEMBL10000468 | 0.73 | GRM8 (0.61) | GRM8GRM4GRM6GRM7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | PTH1R, P4HA1, FGF23 | GRM8 4160/4885GRM4 3644/4885GRM6 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.