SCHEMBL10000545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10000618	0.82	PDK2 (0.38)	PDK2KDM4EALDH1A1HPGDKMT2A
	SCHEMBL10000543	0.81	PDK2 (0.60)	PDK2KDM4EALDH1A1METAP2KMT2A
	SCHEMBL16547424	0.79	PDK2 (0.41)	PDK2ALDH1A1ADRA1AKMT2ACYP1A2
	SCHEMBL1335900	0.79	PDK2 (0.43)	PDK2KDM4EALDH1A1KMT2ACYP1A2
	SCHEMBL10027993	0.77	PLAU (0.41)	PDK2KDM4EALDH1A1HPGDKMT2A
	SCHEMBL10000583	0.74	CYP2A6 (0.42)	PDK2KDM4EALDH1A1CYP1A2CYP2C19
	SCHEMBL24349352	0.72	CYP3A4 (0.42)	PDK2KDM4EALDH1A1HPGDMMP2
	SCHEMBL10000559	0.71	PDK2 (0.38)	PDK2KDM4EALDH1A1HPGDKMT2A
	SCHEMBL68937	0.71	PDK2 (0.57)	PDK2CHRM1ADRA1AKMT2ACYP1A2
	SCHEMBL9936344	0.71	PDK2 (0.56)	PDK2KDM4EALDH1A1HPGDCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.