SCHEMBL10000618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10000619	0.83	PDK2 (0.46)	PDK2KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL10000545	0.82	PDK2 (0.44)	PDK2KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL10028267	0.79	PLAU (0.35)	PDK2KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL1335900	0.75	PDK2 (0.43)	PDK2KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL10000597	0.71	PDK2 (0.36)	PDK2KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL10000583	0.71	CYP2A6 (0.42)	PDK2CYP1A2CYP2C19KDM4EALDH1A1
	SCHEMBL10000543	0.70	PDK2 (0.60)	PDK2KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL16547424	0.69	PDK2 (0.41)	PDK2KMT2ACYP1A2CYP2C19ALDH1A1
	SCHEMBL14252637	0.68	CYP2A6 (0.34)	PDK2KMT2ACYP1A2CYP2C19CYP2A6
	SCHEMBL10000559	0.68	PDK2 (0.38)	PDK2KMT2ACYP1A2CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.