SCHEMBL10000883

SCHEMBL10000883

CC1CCC(c2ccc(Cl)c(F)c2)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.47
SLC6A2 P23975 9/20 0.40
SLC6A3 Q01959 9/20 0.40
SLC6A4 P31645 8/20 0.40
KCNH2 Q12809 6/20 0.36
HTR7 P34969 1/20 0.36
CYP2D6 P10635 5/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RIPK1 Q13546 1/20 0.34
FASN P49327 1/20 0.34
HSD11B1 P28845 1/20 0.33
MAPK14 Q16539 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13408558 1.00 ESR2 (0.47) ESR2SLC6A2SLC6A3SLC6A4KCNH2
SCHEMBL14274435 0.95 ESR2 (0.43) ESR2SLC6A2SLC6A3SLC6A4KCNH2
SCHEMBL15517006 0.91 SLC6A3 (0.42) SLC6A2SLC6A3SLC6A4KCNH2HTR7
SCHEMBL9979948 0.83 ESR2 (0.52) ESR2SLC6A2SLC6A3SLC6A4FASN
SCHEMBL4470188 0.83 ESR2 (0.52) ESR2SLC6A2SLC6A3SLC6A4KCNH2
SCHEMBL15516731 0.83 SLC6A3 (0.46) ESR2SLC6A2SLC6A3SLC6A4KCNH2
SCHEMBL8453891 0.82 FASN (0.41) ESR2CYP2D6FASN
SCHEMBL8453888 0.82 FASN (0.41) ESR2CYP2D6FASN
SCHEMBL8453885 0.82 FASN (0.41) ESR2CYP2D6FASN
SCHEMBL17719303 0.81 ESR2 (0.50) ESR2CYP2D6FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9977294-B2 Liquid crystal display device INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2018-05-22 US disclosed
US-9977294-B2 Liquid crystal display device INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2018-05-22 US disclosed
US-9670410-B2 Liquid crystal composition INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-06-06 US disclosed
US-9670410-B2 Liquid crystal composition INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-06-06 US disclosed
US-9664957-B2 Liquid crystal display device and method of driving the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-05-30 US disclosed
US-9664957-B2 Liquid crystal display device and method of driving the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2017-05-30 US disclosed
US-9617473-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2017-04-11 US disclosed
US-9617473-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2017-04-11 US disclosed
EP-2630217-B1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2016-10-26 EP disclosed
US-9238775-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2016-01-19 US disclosed
US-20150198855-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF DRIVING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2015-07-16 US disclosed
US-20150191650-A1 LIQUID CRYSTAL COMPOSITION INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2015-07-09 US disclosed
US-20150137036-A1 LIQUID CRYSTAL COMPOSITION INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2015-05-21 US disclosed
US-20130208227-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130155338-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-06-20 US disclosed
EP-2423294-A1 Switch element comprising a liquid-crystalline medium Merck Patent GmbH (DE) 2012-02-29 EP disclosed
WO-2011035842-A1 POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2011-03-31 WO disclosed
US-7704566-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2010-04-27 US disclosed
US-7553522-B2 LC-mixtures with low frequency dependence for TFT-displays MERCK PATENT GMBH (DE) 2009-06-30 US disclosed
US-20070034829-A1 liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays MERCK PATENT GMBH (DE) 2007-02-15 US disclosed