SCHEMBL10000940

SCHEMBL10000940

Cc1cc(C(C)C)ccc1-c1ccc(C(C)C)cc1C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
AKR1C3 P42330 14/20 0.46
AKR1C2 P52895 14/20 0.46
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
TRPA1 O75762 1/20 0.40
PTGS1 P23219 1/20 0.40
CACNA1C Q13936 1/20 0.40
PDK2 Q15119 1/20 0.40
AKR1C4 P17516 3/20 0.39
AKR1C1 Q04828 3/20 0.39
AKR1B10 O60218 2/20 0.39
CRHR1 P34998 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10030654 0.91 GLA (0.48) LMNAAKR1C3AKR1C2GLAPOLB
SCHEMBL10030388 0.86 AKR1C3 (0.52) LMNAAKR1C3AKR1C2GLAPOLB
SCHEMBL20676163 0.82 LMNA (0.77) LMNAAKR1C3AKR1C2GAATRPA1
SCHEMBL24910239 0.82 AKR1C3 (0.55) LMNAAKR1C3AKR1C2GLAPOLB
SCHEMBL12868131 0.81 LMNA (0.47) LMNAAKR1C3AKR1C2GAATRPA1
SCHEMBL1109056 0.81 LMNA (0.52) LMNAAKR1C3AKR1C2GAATRPA1
SCHEMBL10416092 0.78 LMNA (0.86) LMNAAKR1C3AKR1C2GAATRPA1
SCHEMBL24910037 0.78 AKR1C3 (0.55) LMNAAKR1C3AKR1C2GLAPOLB
SCHEMBL24781628 0.77 AKR1C3 (0.57) LMNAAKR1C3AKR1C2TSHRPTGS1
SCHEMBL13304198 0.77 LMNA (0.40) LMNAAKR1C3AKR1C2GAATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499664-B2 Polyimide polymer, polyimide film having the same and polyimide laminate having the same MORTECH CORPORATION (TW) 2016-11-22 US disclosed
US-20160122483-A1 POLYIMIDE POLYMER, POLYIMIDE FILM HAVING THE SAME AND POLYIMIDE LAMINATE HAVING THE SAME MORTECH CORPORATION (TW) 2016-05-05 US disclosed
US-9209403-B2 Method for fabricating flexible electrical devices INDUSTRIAL TECHNOLOGY RESEARCH CENTER (TW) 2015-12-08 US disclosed
US-8859715-B2 Polyimide polymer solution, polyimide polymer, transparent film, displaying device and solar cell INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-10-14 US disclosed
US-20130267061-A1 METHOD FOR FABRICATING FLEXIBLE ELECTRICAL DEVICES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-10-10 US disclosed
US-20120160317-A1 POLYIMIDE POLYMER SOLUTION, POLYIMIDE POLYMER, TRANSPARENT FILM, DISPLAYING DEVICE AND SOLAR CELL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-06-28 US disclosed
US-20110155235-A1 POLYIMIDE POLYMERS FOR FLEXIBLE ELECTRICAL DEVICE SUBSTRATE MATERIALS AND FLEXIBLE ELECTRICAL DEVICES COMPRISING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2011-06-30 US disclosed