SCHEMBL24910239

SCHEMBL24910239

CC(C)c1ccc(-c2ccccc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 9/20 0.55
AKR1C2 P52895 9/20 0.55
PDK2 Q15119 1/20 0.50
TRPA1 O75762 3/20 0.46
CRHR1 P34998 2/20 0.44
HSD11B1 P28845 1/20 0.42
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
AKR1C4 P17516 1/20 0.40
AKR1C1 Q04828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10030654 0.91 GLA (0.48) AKR1C3AKR1C2PDK2GLAPOLB
SCHEMBL24910320 0.89 AKR1C3 (0.51) AKR1C3AKR1C2PDK2TRPA1CRHR1
SCHEMBL24910037 0.88 AKR1C3 (0.55) AKR1C3AKR1C2PDK2TRPA1GLA
SCHEMBL24781628 0.84 AKR1C3 (0.57) AKR1C3AKR1C2PDK2TSHRLMNA
SCHEMBL10000940 0.82 LMNA (0.55) AKR1C3AKR1C2PDK2TRPA1CRHR1
SCHEMBL10030388 0.82 AKR1C3 (0.52) AKR1C3AKR1C2PDK2TRPA1CRHR1
SCHEMBL12570858 0.80 CNR2 (0.48) AKR1C3AKR1C2TRPA1HSD11B1LMNA
SCHEMBL15340840 0.79 PTPN5 (0.49) AKR1C3AKR1C2TRPA1HSD11B1TRPM8
SCHEMBL24910185 0.78 AKR1C3 (0.51) AKR1C3AKR1C2PDK2TRPA1CRHR1
SCHEMBL24910091 0.77 AKR1C3 (0.44) AKR1C3AKR1C2PDK2HSD11B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122934-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-25 EP disclosed