Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 3/20 | 0.33 |
| ▸ | TOP1 | P11387 | 3/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000998 | 0.92 | KDM4E (0.30) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10000993 | 0.80 | TOP1 (0.32) | MEN1KMT2AACACATOP1 | |
| SCHEMBL10030712 | 0.80 | SQOR (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10000977 | 0.79 | SQOR (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10000979 | 0.77 | MEN1 (0.32) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10000985 | 0.77 | ADORA1 (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10000974 | 0.77 | ADORA1 (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10000992 | 0.77 | MEN1 (0.32) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL10001001 | 0.76 | ADORA1 (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10000976 | 0.76 | ADORA1 (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475686-B2 | Bridged pyridoquinazoline or phenanthroline compounds and organic semiconducting material comprising that compound | NOVALED AG (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20120012794-A1 | Bridged Pyridoquinazoline or Phenanthroline Compounds and Organic Semiconducting Material Comprising That Compound | NOVALED AG (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120012794-A1 | Bridged Pyridoquinazoline or Phenanthroline Compounds and Organic Semiconducting Material Comprising That Compound | PNPO, SDHB, PAH | KDM4E 2792/4885ALDH1A1 1384/4885MAPT 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.