Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.70 |
| ▸ | AURKA | O14965 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | FLT3 | P36888 | 1/20 | 0.70 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.66 |
| ▸ | XDH | P47989 | 1/20 | 0.66 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.66 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001100 | 0.92 | CYP1B1 (0.69) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL10001086 | 0.91 | CYP1B1 (0.67) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL10001101 | 0.91 | HSD17B2 (0.70) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL30787094 | 0.87 | CYP1B1 (0.82) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL6244246 | 0.87 | CYP1B1 (0.82) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL10001087 | 0.86 | CYP1B1 (0.70) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL10001098 | 0.86 | KDM4E (0.61) | CYP1B1CYP1A1FLT3HDAC6CYP1A2 | |
| SCHEMBL10001079 | 0.85 | MAPT (0.67) | CYP1B1CYP1A1FLT3CYP1A2IP6K2 | |
| SCHEMBL10001095 | 0.83 | CYP1B1 (0.67) | CYP1B1CYP1A1AURKAKDRFLT3 | |
| SCHEMBL8069022 | 0.82 | FLT3 (0.86) | CYP1B1CYP1A1AURKAKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | HTR2C, GRIN2C, HTR5A | CYP1B1 1037/4885CYP1A1 416/4885AURKA 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.