Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.86 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.86 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.86 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.86 |
| ▸ | AURKA | O14965 | 1/20 | 0.86 |
| ▸ | KDR | P35968 | 1/20 | 0.86 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.86 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.82 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 4/20 | 0.82 |
| ▸ | MAPT | P10636 | 4/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | NPC1 | O15118 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | GFER | P55789 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.82 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.82 |
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | THRB | P10828 | 1/20 | 0.82 |
| ▸ | APEX1 | P27695 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799172 | 1.00 | FLT3 (0.86) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Eupatilin SCHEMBL29568655 | 0.93 | HDAC6 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Eupatilin SCHEMBL1033509 | 0.93 | HDAC6 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Eupatilin SCHEMBL29926197 | 0.93 | HDAC6 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Eupatorin SCHEMBL29386042 | 0.93 | CYP1A1 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Eupatorin SCHEMBL30334912 | 0.93 | CYP1A1 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Eupatorin SCHEMBL555597 | 0.93 | CYP1A1 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| SCHEMBL8062995 | 0.91 | CYP1A1 (0.88) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Jaceosidine SCHEMBL29926544 | 0.90 | HSD17B2 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA | |
| Jaceosidine SCHEMBL3960077 | 0.90 | HSD17B2 (1.00) | FLT3CYP1A1CYP1B1HDAC6AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-02-02 | — | — | US | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029066-A1 | USE OF FLAVONES FOR TREATING PSYCHIATRIC DISORDERS WITH SENSORIMOTOR GATING DEFICITS | HTR2C, GRIN2C, HTR5A | FLT3 3391/4885CYP1A1 416/4885CYP1B1 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.