Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 17/20 | 0.69 |
| ▸ | CA12 | O43570 | 16/20 | 0.69 |
| ▸ | CA2 | P00918 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.69 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.69 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.69 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.69 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.69 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 10/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.53 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.53 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.53 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13543237 | 0.87 | HTT (0.66) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL1034640 | 0.82 | CA9 (1.00) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL13651238 | 0.82 | CA9 (0.76) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL26599943 | 0.82 | CA9 (0.76) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL3663 | 0.82 | CA9 (1.00) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL23391020 | 0.81 | CA9 (0.97) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL20636804 | 0.81 | CA9 (0.97) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL20636781 | 0.81 | CA9 (0.97) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL23630240 | 0.81 | CA9 (0.97) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| Probenecid SCHEMBL22325443 | 0.81 | CA9 (0.97) | CA9CA12CA2RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |
| US-8093427-B2 | Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-01-10 | — | — | US | disclosed |
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306668-A1 | CONSTRUCTION AND SCREENING OF SOLUTION-PHASE DERIVED LIBRARY OF FENBUFEN AND ETHACRYNIC ACID | CYP4F2, ACR, CYP4F3 | CA9 2665/4885CA12 3121/4885CA2 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.