SCHEMBL10001348

SCHEMBL10001348

Cc1nn(-c2cc(CC(C)Cl)c(Cl)cc2F)c(=O)n1C(F)F

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016808 0.90 PPOX (0.47) PPOX
SCHEMBL8013578 0.88 PPOX (0.45) PPOX
SCHEMBL29394862 0.87 PPOX (0.44) PPOX
SCHEMBL29355476 0.87 PPOX (0.44) PPOX
SCHEMBL16487876 0.87 PPOX (0.44) PPOX
SCHEMBL38807 0.87 PPOX (0.44) PPOX
SCHEMBL3302402 0.87 PPOX (0.44) PPOX
SCHEMBL28957594 0.87 PPOX (0.44) PPOX
SCHEMBL28813883 0.86 PPOX (0.44) PPOX
Carfentrazone-Ethyl SCHEMBL38936 0.85 PPOX (0.43) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883681-B2 Sugarcane harvest aid FMC CORPORATION (US) 2014-11-11 US disclosed
US-8399382-B2 Cotton growth regulator FMC CORPORATION (US) 2013-03-19 US disclosed
US-8119567-B2 Method for control of cyanobacterial algae, mosses, liverworts, hornworts and other bryophytes FMC CORPORATION (US) 2012-02-21 US disclosed
US-20090062122-A1 Cotton Growth Regulator FMC CORPORATION (US) 2009-03-05 US disclosed
US-20080312081-A1 Method for Control of Ground Shoots of Vines and Other Trunk Vegetation FMC CORPORATION (US) 2008-12-18 US disclosed
US-20080261813-A1 Method for ripening sugarcane crops, which comprises applying an effective amount of a protoporphyrinogen oxidase enzyme-inhibiting compound such as carfentrazone ethyl and certain metabolites thereof FMC CORPORATION (US) 2008-10-23 US disclosed
US-20070259788-A1 Method for Control of Cyanobacterial Algae, Mosses, Liverworts, Hornworts and Other Bryophytes FMC CORPORATION 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261813-A1 Method for ripening sugarcane crops, which comprises applying an effective amount of a protoporphyrinogen oxidase enzyme-inhibiting compound such as carfentrazone ethyl and certain metabolites thereof PPOX, CYP4Z1, CYP4F12 PPOX 1/4885
US-20080312081-A1 Method for Control of Ground Shoots of Vines and Other Trunk Vegetation PPOX, CYP4F2, CYP4F3 PPOX 1/4885
US-20070259788-A1 Method for Control of Cyanobacterial Algae, Mosses, Liverworts, Hornworts and Other Bryophytes CYP3A43, PPOX, CYP2W1 PPOX 2/4885
US-20090062122-A1 Cotton Growth Regulator PPOX, CYP4Z1, CYP4X1 PPOX 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.