Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CETP | P11597 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | THRB | P10828 | 3/20 | 0.68 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.67 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.50 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12795857 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL31003583 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL4169155 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL6661598 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL12994189 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL1976275 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL4140908 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL12316166 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL4133159 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL30652483 | 1.00 | MAPT (0.71) | MAPTCYP2D6MAPK1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9578944-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-28 | — | — | US | disclosed |
| US-9578944-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-28 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565916-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565915-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565915-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565916-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9474700-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2016-10-25 | — | — | US | disclosed |
| US-9474700-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2016-10-25 | — | — | US | disclosed |
| US-20140311517-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2014-10-23 | — | — | US | disclosed |
| US-20140305464-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2014-10-16 | — | — | US | disclosed |
| US-20140305464-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2014-10-16 | — | — | US | disclosed |
| WO-2014074812-A1 | METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR | L'OREAL (FR) | 2014-05-15 | — | — | WO | disclosed |
| WO-2013071191-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013071182-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| US-8177860-B2 | Oxidation hair dye and hair bleach | ARIMINO CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8177860-B2 | Oxidation hair dye and hair bleach | ARIMINO CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20110182839-A1 | OXIDATION HAIR DYE AND HAIR BLEACH | ARIMINO CO., LTD. (JP) | 2011-07-28 | — | — | US | disclosed |
| US-20110182839-A1 | OXIDATION HAIR DYE AND HAIR BLEACH | ARIMINO CO., LTD. (JP) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182839-A1 | OXIDATION HAIR DYE AND HAIR BLEACH | SGMS2, SGMS1, LRAT | MAPT 2002/4885CYP2D6 2074/4885MAPK1 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.