SCHEMBL4169155

SCHEMBL4169155

CCCCCCCCCCCCCC=CC(O)C(CO)NC(=O)C(O)CCCCCCCCCCCCCC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.71
CYP2D6 P10635 3/20 0.71
MAPK1 P28482 3/20 0.71
TP53 P04637 2/20 0.71
CYP1A2 P05177 2/20 0.71
CYP2C9 P11712 2/20 0.71
CYP2C19 P33261 2/20 0.71
CETP P11597 7/20 0.68
MEN1 O00255 4/20 0.68
KMT2A Q03164 4/20 0.68
THRB P10828 3/20 0.68
ASAH1 Q13510 2/20 0.67
ASAH2 Q9NR71 2/20 0.65
ALDH1A1 P00352 2/20 0.59
KDM4E B2RXH2 1/20 0.59
SPHK2 Q9NRA0 3/20 0.50
SPHK1 Q9NYA1 3/20 0.50
GMNN O75496 2/20 0.50
LMNA P02545 2/20 0.50
GLA P06280 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12795857 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL31003583 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL10001355 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL6661598 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL12994189 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL1976275 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL4140908 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL12316166 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL4133159 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL30652483 1.00 MAPT (0.71) MAPTCYP2D6MAPK1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3086767-B1 PROCESS FOR TREATING KERATIN FIBRES WITH AN OXIDISED POLYSACCHARIDE AND A SPHINGOSINE COMPOUND OREAL (FR) 2018-06-13 EP claimed
US-11730682-B2 Self-standing cosmetic sheet L'OREAL (FR) 2023-08-22 US disclosed
EP-2836187-B1 SELF-STANDING COSMETIC SHEET OREAL (FR) 2021-12-08 EP disclosed
EP-2198849-B2 Composition for oxidising dyeing of keratinous fibres OREAL (FR) 2020-11-11 EP disclosed
US-20180235849-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2018-08-23 US disclosed
US-9949897-B2 Self-standing cosmetic sheet L'OREAL (FR) 2018-04-24 US disclosed
US-20150209243-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2015-07-30 US disclosed
EP-2836187-A1 SELF-STANDING COSMETIC SHEET L'Oréal (FR) 2015-02-18 EP disclosed
WO-2013153678-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2013-10-17 WO disclosed
US-8268805-B2 Use of ceramides for depigmenting the skin L'OREAL (FR) 2012-09-18 US disclosed
US-20090192124-A1 USE OF CERAMIDES FOR DEPIGMENTING THE SKIN L'OREAL (FR) 2009-07-30 US disclosed
WO-2008015366-A2 cosmetic treatment process comprising the application of an anhydrous composition in the form of a water-soluble film in the presence of a fluid comprising water vapour L'OREAL (FR) 2008-02-07 WO disclosed
WO-2008015367-A2 COSMETIC TREATMENT PROCESS USING AN ANHYDROUS COMPOSITION IN THE FORM OF A FILM COMPRISING A FILM-FORMING POLYMER AND A CONDITIONING AGENT L'OREAL (FR) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150209243-A1 SELF-STANDING COSMETIC SHEET CUTA, SUCLG1, SIGLEC7 MAPT 4402/4885CYP2D6 4653/4885MAPK1 3932/4885
US-20180235849-A1 SELF-STANDING COSMETIC SHEET CUTA, DSG1, SUCLG1 MAPT 3846/4885CYP2D6 4100/4885MAPK1 3774/4885
US-20090192124-A1 USE OF CERAMIDES FOR DEPIGMENTING THE SKIN CERS2, CERT1, ASAH2 MAPT 3244/4885CYP2D6 2906/4885MAPK1 1578/4885
US-11730682-B2 Self-standing cosmetic sheet CUTA, DSG1, SUCLG1 MAPT 3846/4885CYP2D6 4100/4885MAPK1 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.