⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573584 | 0.86 | — | — | |
| SCHEMBL4671779 | 0.84 | — | — | |
| SCHEMBL2705361 | 0.79 | L3MBTL1 (0.32) | — | |
| SCHEMBL2031063 | 0.79 | — | — | |
| SCHEMBL1488954 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL1949038 | 0.73 | — | — | |
| SCHEMBL11671711 | 0.70 | — | — | |
| SCHEMBL2089722 | 0.70 | — | — | |
| SCHEMBL4681202 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL1680245 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101812029-B | Method for producing 5-halogenolinear alkyl tetrazole | NANTONG HUAFENG CHEMICAL CO | 2012-02-15 | — | — | CN | claimed |
| CN-101805306-A | Production method of 5-chloromethyl tetrazole or 5-chloroethyl tetrazole | NANTONG HUAFENG CHEMICAL CO | 2010-08-18 | — | — | CN | claimed |
| US-RE36080-E | Method for augmenting fetal hemoglobin | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA (US) | 1999-02-02 | — | — | US | claimed |
| EP-0371789-B1 | Medicament for augmenting fetal hemoglobin | CHILDRENS HOSP MEDICAL CENTER (US) | 1997-01-02 | — | — | EP | claimed |
| US-5025029-A | Method for augmenting fetal hemoglobin | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA (US) | 1991-06-18 | — | — | US | claimed |
| EP-0371789-A2 | Medicament for augmenting fetal hemoglobin | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA (US) | 1990-06-06 | — | — | EP | claimed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |
| US-8906852-B2 | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2014-12-09 | — | — | US | disclosed |
| US-8906852-B2 | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2014-12-09 | — | — | US | disclosed |
| US-5216004-A | Administering a butyrate analog alone or in mixture with activin and inhibin | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTH CALIFORNIA (US) | 1993-06-01 | — | — | US | disclosed |
| US-5025029-A | Method for augmenting fetal hemoglobin | CHILDREN'S HOSPITAL MEDICAL CENTER OF NORTHERN CALIFORNIA (US) | 1991-06-18 | — | — | US | disclosed |
| US-4461772-A | SYNERGISTIC MIXTURE OF SUBSTITUTED TETRAZOLE AND 1-CYANO-2-METHYLSULFAMIDOETHANE | SDS BIOTECH CORPORATION (US) | 1984-07-24 | — | — | US | disclosed |
| EP-0047661-B1 | ADDITIVES, FEED COMPOSITIONS AND METHODS FOR IMPROVING RUMINANT FEED UTILIZATION | SDS BIOTECH CORPORATION (US) | 1984-06-06 | — | — | EP | disclosed |
| US-4423224-A | FEED UTILIZATION EFFICIENCY | SDS BIOTECH CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0047661-A1 | Additives, feed compositions and methods for improving ruminant feed utilization | SDS BIOTECH CORPORATION (US) | 1982-03-17 | — | — | EP | disclosed |
| US-4013596-A | Adhesive tetrazole polymers and process of making therefor | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1977-03-22 | — | — | US | disclosed |