Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 6/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 5/20 | 1.00 |
| ▸ | HSP90B1 | P14625 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 4/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | AHCY | P23526 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119006 | 1.00 | ADORA3 (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| SCHEMBL8373480 | 0.91 | ADORA3 (0.85) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL29361791 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL30656108 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL30036568 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL19928417 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL16585523 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL18089301 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL19928418 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR | |
| Neca SCHEMBL12119012 | 0.88 | TSHR (1.00) | ADORA3ADORA2BADORA1HSP90B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165432-A1 | 3,6-DISUBSTITUTED-2-PYRIDINALDOXIME SCAFFOLDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-08-20 | — | — | WO | disclosed |
| US-8158376-B2 | Bisubstrate fluorescent probe binding to protein kinases | UNIVERSITY OF TARTU (EE) | 2012-04-17 | — | — | US | disclosed |
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | UNIVERSITY OF TARTU (EE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233743-A1 | BISUBSTRATE FLUORESCENT PROBE BINDING TO PROTEIN KINASES | ADK, PRKCH, DMPK | ADORA3 425/4885ADORA2B 713/4885ADORA1 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.