SCHEMBL10001468

SCHEMBL10001468

CC1(C)c2ccccc2-c2cc3c4cc(-c5ccc6c(c5)c5ccccc5n6-c5cccc6ccccc56)ccc4n(-c4ccccc4)c3cc21

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.36
▸ ATM Q13315 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ MAPT P10636 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ PTGER4 P35408 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ CNR1 P21554 1/20 0.30
▸ CNR2 P34972 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19653513 1.00 KDM4E (0.36) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19652849 0.96 KDM4E (0.32) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19653174 0.96 KDM4E (0.32) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19653511 0.96 KDM4E (0.36) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19653148 0.96 KDM4E (0.36) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19653201 0.95 KDM4E (0.32) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19652978 0.95 KDM4E (0.32) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL23862298 0.95 MEN1 (0.36) KDM4EMAPTMEN1MAPK1KMT2A
SCHEMBL10001516 0.93 MAPT (0.37) KDM4EL3MBTL1MAPTMEN1MAPK1
SCHEMBL18518996 0.92 KDM4E (0.35) KDM4EATML3MBTL1MAPTPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2021-09-28 — — US disclosed
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-11-30 — — US disclosed
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-11-30 — — US disclosed
EP-2599773-B1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2017-03-29 — — EP disclosed
WO-2016076629-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-05-19 — — WO disclosed
US-9196837-B2 Compound having indenocarbazole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-11-24 — — US disclosed
US-9196837-B2 Compound having indenocarbazole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-11-24 — — US disclosed
EP-2599773-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2013-06-05 — — EP disclosed
US-20130126856-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2013-05-23 — — US disclosed
US-20130126856-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2013-05-23 — — US disclosed
WO-2012014500-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 (JP) 2012-02-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130747-B2 Plurality of host materials and an organic electroluminescence device comprising the same SOD1, TERT, TELO2 KDM4E 2736/4885ATM 3138/4885L3MBTL1 59/4885
US-20130126856-A1 COMPOUND HAVING INDENOCARBAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, SLCO1B1, SLCO2A1 KDM4E 1716/4885ATM 4800/4885L3MBTL1 2253/4885
US-20170342057-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 KDM4E 2915/4885ATM 3046/4885L3MBTL1 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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