Isophthalic Acid

Isophthalic Acid

SCHEMBL1000200

NNC(=O)NN.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
CYP2C9 P11712 1/20 0.61
HPGD P15428 1/20 0.61
HSD17B10 Q99714 1/20 0.61
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA12 O43570 1/20 0.54
CA6 P23280 1/20 0.54
CA9 Q16790 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.50
KMO O15229 1/20 0.50
PKM P14618 1/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
UNG P13051 1/20 0.48
DAO P14920 1/20 0.48
TSHR P16473 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL14938995 0.86 TSHR (0.67) CYP1A2CYP2C9HPGDHSD17B10CA1
SCHEMBL1246493 0.85 KDM4E (0.66) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL4882153 0.84 CA12 (0.65) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL4614187 0.84 CA12 (0.65) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL28462260 0.83 CA12 (0.71) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL147366 0.83 CA12 (0.71) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL22462 0.83 CA12 (0.71) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL20500514 0.83 CA12 (0.71) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL28756611 0.83 CA12 (0.71) CYP1A2CYP2C9HPGDHSD17B10CA1
Isophthalic Acid SCHEMBL2512374 0.83 CA12 (0.71) CYP1A2CYP2C9HPGDHSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868102-B2 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced TORAY INDUSTRIES, INC. (JP) 2011-01-11 US disclosed
EP-1602680-B1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES (JP) 2010-12-22 EP disclosed
EP-2258746-A2 A method for producing an aromatic polymer, film, electrolyte membrane and separator Toray Industries, Inc. (JP) 2010-12-08 EP disclosed
US-20100016521-A1 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced MORIYAMA HIDEKI 2010-01-21 US disclosed
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same MORIYAMA HIDEKI 2009-07-16 US disclosed
US-7511112-B2 Aromatic polymer, film, electrolyte membrane and separator TORAY INDUSTRIES, INC. (JP) 2009-03-31 US disclosed
US-20060204812-A1 Aromatic polymer, film, electrolyte membrane and separator MORIYAMA HIDEKI 2006-09-14 US disclosed
EP-1602680-A1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES, INC. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same OGFOD1, ODC1, OTC CYP1A2 1214/4885CYP2C9 450/4885HPGD 286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.