⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409875 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL7016412 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL2679027 | 0.78 | HSD17B10 (0.33) | — | |
| SCHEMBL9463108 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL23142615 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL11572261 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL17675058 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL5749857 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL8008844 | 0.74 | — | — | |
| SCHEMBL9452573 | 0.70 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311802-A1 | BIARYL INHIBITORS OF BRUTON'S TYROSINE KINASE | BIOGEN MA INC. | 2016-10-27 | — | — | US | disclosed |
| US-8901415-B2 | Conducting polymer to which pyrene compounds are introduced, and organic solar cell using same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2014-12-02 | — | — | US | disclosed |
| US-8519068-B2 | Conductive polymer containing carbazole, and organic photovoltaic device using same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2013-08-27 | — | — | US | disclosed |
| US-20120305082-A1 | CONDUCTING POLYMER TO WHICH PYRENE COMPOUNDS ARE INTRODUCED, AND ORGANIC SOLAR CELL USING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-12-06 | — | — | US | disclosed |
| US-20120018715-A1 | CONDUCTIVE POLYMER CONTAINING CARBAZOLE, AND ORGANIC PHOTOVOLTAIC DEVICE USING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-01-26 | — | — | US | disclosed |