Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11905000 | 0.82 | NOD2 (0.56) | TSHRLMNAKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL10004969 | 0.73 | NOD2 (0.54) | TSHRLMNAKDM4EL3MBTL1NOD2 | |
| SCHEMBL10003723 | 0.71 | NOD2 (0.56) | TSHRLMNAKDM4EL3MBTL1NOD2 | |
| SCHEMBL10003940 | 0.70 | NOD2 (0.51) | TSHRLMNAKDM4EL3MBTL1NOD2 | |
| SCHEMBL10003089 | 0.70 | PTGDR2 (0.39) | TSHRLMNAKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL10002916 | 0.70 | NOD2 (0.62) | TSHRLMNAKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL2005697 | 0.67 | NOD2 (0.53) | TSHRKDM4ECYP2C9NOD2NOD1 | |
| SCHEMBL31332525 | 0.67 | KMT2A (0.50) | TSHRLMNAKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL11905170 | 0.66 | NOD2 (0.56) | TSHRLMNAKDM4EL3MBTL1CYP2C9 | |
| SCHEMBL10002784 | 0.65 | ALOX5 (0.39) | KDM4ECYP2C9NOD2NOD1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471786-A1 | AMINOPYRAZOLE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-07-04 | — | — | EP | disclosed |