Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005071 | 0.83 | MAPT (0.51) | LMNATP53HSD17B10NPSR1ALDH1A1 | |
| SCHEMBL10004971 | 0.82 | HSD17B10 (0.54) | LMNATP53HSD17B10NPSR1ALDH1A1 | |
| SCHEMBL10005165 | 0.81 | MAPT (0.53) | TP53HSD17B10NPSR1ALDH1A1HTT | |
| SCHEMBL10005128 | 0.81 | HSD17B10 (0.47) | TP53HSD17B10ALDH1A1MAPTTHRB | |
| SCHEMBL10315955 | 0.79 | NPC1 (0.59) | TP53HSD17B10NPSR1ALDH1A1MAPT | |
| SCHEMBL10291387 | 0.74 | NPC1 (0.62) | TP53HSD17B10NPSR1ALDH1A1MAPT | |
| SCHEMBL3345659 | 0.73 | HSD17B10 (0.55) | LMNATP53HSD17B10NPSR1ALDH1A1 | |
| SCHEMBL8964777 | 0.71 | KDM6B (0.61) | TP53HSD17B10NPSR1ALDH1A1MAPT | |
| SCHEMBL30831262 | 0.70 | SMN1; SMN2 (0.54) | TP53HSD17B10TSHRUSP2P2RY14 | |
| SCHEMBL16156477 | 0.70 | NPC1 (0.53) | TP53HSD17B10NPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155892-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2015-03-18 | — | — | EP | disclosed |
| EP-2471944-A1 | Novel peptidase substrates | bioMérieux (FR) | 2012-07-04 | — | — | EP | disclosed |